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bout This Research Topic is the follow up to Insights in Addictive Disorders: 2021 We are now entering the third decade of the 21st Century, and, especially in the last years, the achievements made by scientists have been exceptional, leading to major advancements in the fast-growing field of Addictive Disorders. Frontiers has organized a series of Research Topics to highlight the latest advancements in research across the field of Addictive Disorders, with articles from the Associate Members of our accomplished Editorial Boards. This editorial initiative of particular relevance, led by Dr. Khazaal, Specialty Chief Editor of the Addictive Disorders section, is focused on new insights, novel ...
The Reeler mutation was so named because of the alterations in gait that characterize homozygous mice. Several decades after the description of the Reeler phenotype, the mutated protein was discovered and named Reelin (Reln). Reln controls a number of fundamental steps in embryonic and postnatal brain development. A prominent embryonic function is the control of radial neuronal migration. As a consequence, homozygous Reeler mutants show disrupted cell layering in cortical brain structures. Reln also promotes postnatal neuronal maturation. Heterozygous mutants exhibit defects in dendrite extension and synapse formation, correlating with behavioral and cognitive deficits that are detectable at...
Blockchain’s significant advances since 2020 – including a plethora of new use cases – have necessitated a comprehensive revision of the first edition of this matchless resource. While new chapters and topics have been added, the handbook still follows the systematic and structured approach of the first edition. Each contributor – all of them practitioners experienced with blockchain projects within their respective areas of expertise and specific jurisdictions – elucidates the implications of blockchain technology and related legal issues under such headings as the following: understanding blockchain from a technological point of view; regulatory aspects of blockchain; smart contr...
Building on the strengths of the first edition, the second edition of Latin American Classical Composers: A Biographical Dictionary presents expanded and updated coverage of its topic with an aim to be comprehensive. The authors have conducted exhaustive research to fill in gaps and correct minor errors in the first edition, adding young composers and documenting deaths since 1996, when the first edition appeared. Hundreds of composers are represented in this volume, which presents biographical data, including dates of birth and death, personal information about composers' background and training, and a selective listing of each composer's works. Sources for further study are noted within each entry. An index of composers by country rounds out this work.
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