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This book contributes to better understand how lifestyle modulations can effectively halt the emergence and progression of human diseases. The book will allow the reader to gain a better understanding of the mechanisms by which the environment interferes with the bio-molecular regulatory processes underlying the emergence and progression of complex diseases, such as cancer. Focusing on key and early cellular bio-molecular events giving rise to the emergence of degenerative chronic disease, it builds on previous experience on the development of multi-cellular organisms, to propose a mathematical and computer based framework that allows the reader to analyze the complex interplay between bio-molecular processes and the (micro)-environment from an integrative, mechanistic, quantitative and dynamical perspective. Taking the wealth of empirical evidence that exists it will show how to build and analyze models of core regulatory networks involved in the emergence and progression of chronic degenerative diseases, using a bottom-up approach.
Annotation This publications addresses the perceptions of violence by the people living in poor communities in Guatemala. It provides the results of a participatory study of violence conducted in urban low-income communities.
"With this ground-breaking book, Kenton V. Stone presents to North American readers one of the most intriguing writers to emerge out of Latin America in recent years, Uruguay's Carlos Martinez Moreno. Martinez Moreno started writing in the 1960s and achieved international reknown in 1981 when he was awarded Mexico's international fiction prize (by a panel including Gabriel Garcia Marquez, Julio Cortazar, and Ariel Dorfman) for his novel El color que el infierno me escondiera - a novel which, as the title suggests, takes the classic work of Dante Allighieri as its model. Stone's study of Martinez Moreno's novels has a dual purpose. The first purpose is to show that Martinez Moreno is a writer...
The volume shows how economic analysis can explain the causes, conduct, and consequences of conflict.
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Why the Victims Law Applies to Me is an analysis of Colombian political philosophy, based on the authors own experiences, and departs from a specific historical context and liberal approach. The author presents a new approach to Latin Americans and Colombians realities, and denounces the misrepresentations of Colombias History, past and present. He also proposes solutions and a development platform to envision a future with optimism. Jaramillo reveals the current and past perpetrators of the violence in Colombia, denounces the public servants that plunder the countrys institutions, and relentlessly calls for the need for the State to provide Ethical and Moral education through mandatory scho...
An integrated approach to the economics of sovereign default Fiscal crises and sovereign default repeatedly threaten the stability and growth of economies around the world. Mark Aguiar and Manuel Amador provide a unified and tractable theoretical framework that elucidates the key economics behind sovereign debt markets, shedding light on the frictions and inefficiencies that prevent the smooth functioning of these markets, and proposing sensible approaches to sovereign debt management. The Economics of Sovereign Debt and Default looks at the core friction unique to sovereign debt—the lack of strong legal enforcement—and goes on to examine additional frictions such as deadweight costs of ...
This volume presents a selection of contributions to the XXIV Villa Mondragone International Economic Seminar on “Public debt, global governance and economic dynamism”. For the past 23 years, the Seminar has provided an ideal opportunity to meet and discuss the most topical issues in economic research. The quality of the scientific contributions and ensuing debates has consistently been outstanding owing to the participation of leading experts, and the most recent Seminar was no exception. The Seminar was held against the backdrop of high levels of public debt, especially in Europe, combined with very low growth in productivity. Furthermore, markets have been dominated by financial insta...
Los Zetas represent a new generation of ruthless, sadistic pragmatists in Mexico and Central America who are impelling a tectonic shift among drug trafficking organizations in the Americas. Mexico's marines have taken down the cartel's top leaders; nevertheless, these capos and their desperados have forever altered how criminal business is conducted in the Western Hemisphere. This narrative brings an unprecedented level of detail in describing how Los Zetas became Mexico's most diabolical criminal organization before suffering severe losses. In their heyday, Los Zetas controlled networks of American police, politicians, judges, and businessmen. The Mexican government is losing its "war on dr...