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Transport Across Natural and Modified Biological Membranes and its Implications in Physiology and Therapy
This book elucidates the mechanisms involved in biological membrane functions. It describes the new modalities and characterization for basic in vitro as well as computer models of biological membranes. Biological membranes are analyzed in terms of advances in molecular dynamics. The individual chapters provide an in depth analysis of images from various biological models. The potential of membrane models in the context of treatment trials is discussed. The authors present new insights and current concepts for treatment procedures (nanocarriers, electroporation, channel blockers).
Intelligent Information and Database Systems
The two-volume proceedings of the ACIIDS 2016 conference, LNAI 9621 + 9622, constitutes the refereed proceedings of the 8th Asian Conference on Intelligent Information and Database Systems, held in Da Nang, Vietnam, in March 2016. The total of 153 full papers accepted for publication in these proceedings was carefully reviewed and selected from 392 submissions. They were organized in topical sections named: knowledge engineering and semantic Web; social networks and recommender systems; text processing and information retrieval; database systems and software engineering; intelligent information systems; decision support and control systems; machine learning and data mining; computer vision t...
Treatment of Metastatic Melanoma
Surgery continues to be the mainstay treatment for melanoma localized to the primary tumor and/or lymph nodes. Results from randomized controlled trials indicate that sentinel node biopsy for the treatment of cutaneous melanoma of intermediate thickness has a beneficial effect on recurrence rates, and adjuvant radiotherapy to regional lymph node fields following surgical resection reduces loco-regional recurrence in patients at high risk of relapse. Isolated limb perfusion, electrochemotherapy, and photodynamic therapy continue to be evaluated for treatment of stage IV disease. However, the greatest excitement in new treatment has been with targeted therapies for genetic mutations. In particular, the promising results of partial and complete tumor response in stage IV disease from early phase trials of the B-RAF kinase inhibitors. This book provides a contemporary insight into the therapeutic treatment options for patients with metastatic melanoma and is relevant to clinicians and researchers worldwide. In addition, an update on current clinical trials for melanoma treatment has been included, and two chapters have been reserved to discuss the treatment of oral and uveal melanoma.
Intelligent Information and Database Systems: Recent Developments
This book presents research reports selected to indicate the state of the art in intelligent and database systems and to promote new research in this field. It includes 34 chapters based on original research presented as posters at the 11th Asian Conference on Intelligent Information and Database Systems (ACIIDS 2019), held in Yogyakarta, Indonesia on 8–11 April 2019. The increasing use of intelligent and database systems in various fields, such as industry, medicine and science places those two elements of computer science among the most important directions of research and application, which currently focuses on such key technologies as machine learning, cloud computing and processing of...
Nanoarchitectonics for Brain Drug Delivery
This book discusses basics of brain diseases and the role of nanobiotechnology in existing treatment options for neurodegenerative disorders. It begins with an overview of brain diseases and the need for novel drug-delivery approaches. It highlights the current route for the intranasal advanced drug-delivery systems for brain diseases. It also discusses innovative categories of drug-delivery systems, including mesoporous silica nanoparticles, polymeric nanocarriers, and lipid-based nanocarriers through multi-responsive DDSs and their implications in brain disorders. Features: Includes an overview of brain diseases and highlights the need for novel drug-delivery approaches Focuses on theoreti...
Antioxidant Enzyme
Free radicals are constantly formed in living cells and removed by antioxidant defenses. Antioxidant enzymes are the main line of defense against free radicals in animal and plant cells. Uncontrolled generation ROS are involved in a number of human disease states, including diabetes and cancer due to disturbance in cellular and molecular processes including cell growth, differentiation and proliferation. When cells are exposed to oxidative stress a defense system endorses the expression and regulation of number of antioxidant enzymes as a defense mechanism to protect them from the damage induced by free radicals. Based on this fact, the book "Antioxidant Enzymes" was designed to overview the importance of the antioxidant enzymes in human and plant cells against toxic free radicals, their relationship with several pathophysiologic processes and their possible therapeutic application.
Recent Challenges in Intelligent Information and Database Systems
This volume constitutes the refereed proceedings of the 13th Asian Conference on Intelligent Information and Database Systems, ACIIDS 2021, held in Phuket, Thailand, in April 2021. The total of 35 full papers accepted for publication in these proceedings were carefully reviewed and selected from 291 submissions. The papers are organized in the following topical sections: data mining and machine learning methods; advanced data mining techniques and applications; intelligent and contextual systems; natural language processing; network systems and applications; computational imaging and vision; decision support and control systems; data modelling and processing for Industry 4.0.
Electrically Active Materials For Medical Devices
Stress induced electrical charges, action potential and electret behavior of bone, muscles, skin and nerve cells have been known for some time. Electrically Active Materials for Medical Devices builds on this knowledge and encourages readers to understand and exploit electrical activity in biomaterials from native, derived, or completely synthetic origin, or a combination thereof. It presents data and insights from both historic and contemporary research that spans over six decades with a view to generate convergence of interdisciplinary knowledge and skills.Divided into four parts, this book first introduces the reader to a general overview of electrically active materials in biology and bi...
Intelligent Information and Database Systems
This volume constitutes the refereed proceedings of the 12th Asian Conference on Intelligent Information and Database Systems, ACIIDS 2020, held in Phuket, Thailand, in March 2020. The total of 50 full papers accepted for publication in these proceedings were carefully reviewed and selected from 180 submissions. The papers are organized in the following topical sections: advanced big data, machine learning and data mining; industry applications of intelligent methods and systems; artificia intelligence, optimization, and databases in practical applications; intelligent applications of internet of things; recommendation and user centric applications of intelligent systems.
