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Who Runs? Psychological, Physiological and Pathophysiological Aspects of Recreational Endurance Athletes
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Multiscale Mechanobiology of Bone Remodeling and Adaptation
The book presents state-of-the-art developments in multiscale modeling and latest experimental data on multiscale mechanobiology of bone remodeling and adaptation including fracture healing applications. The multiscale models include musculoskeletal models describing bone-muscle interactions during daily activities such as walking or running, micromechanical models for estimation of bone mechanical properties, bone remodeling and adaptation models, cellular models describing the complex bone-cell interactions taking into account biochemical and biomechanical regulatory factors. Also subcellular processes are covered including arrangement of actin filaments due to mechanical loading and change of receptor configurations.
Biomechanical Performance and Relevant Mechanism of Physical Medicine and Rehabilitation for Neuromusculoskeletal Disorders
Biomechanical performance is a key to evaluating effectiveness in physical medicine and rehabilitation for neuromusculoskeletal disorders. Assessments can be applied to degenerative dysfunction (e.g., falls or knee osteoarthritis in older adults) and sports-related injuries (e.g., ankle sprain or anterior cruciate ligament injury). Patients' body movements and daily activity functions can be compared to the state of pre-injury condition or to the level of healthy individuals. Some cutting-edge studies have gone a step further and used biomechanical performance to develop physical medicine and rehabilitation approaches and explore the mechanisms behind their effectiveness. However, such studi...
Computational Systems Biology
Systems Biology is concerned with the quantitative study of complex biosystems at the molecular, cellular, tissue, and systems scales. Its focus is on the function of the system as a whole, rather than on individual parts. This exciting new arena applies mathematical modeling and engineering methods to the study of biological systems. This book is the first of its kind to focus on the newly emerging field of systems biology with an emphasis on computational approaches. The work covers new concepts, methods for information storage, mining and knowledge extraction, reverse engineering of gene and metabolic networks, as well as modelling and simulation of multi-cellular systems. Central themes include strategies for predicting biological properties and methods for elucidating structure-function relationships.
Cross and Sword
From conquistadores and explorers to Protestants, peasants and priests, eyewitnesses give narrative to the triumphs and tragedies of Latin America's religious development.
Cross-Disciplinary Approaches to Characterize Gait and Posture Disturbances in Aging and Related Diseases, volume II
Aging introduces disturbances to the gait and posture of individuals. Such alterations can originate or result from a wide range of causes making it challenging to understand when modifications are related to pathological or physiological causes. Many disciplines come together to perform this kind of analysis (e.g. computational and experimental mechanics, image processing, medicine, biology, physiology, machine learning, and data science). Gait analysis is particularly sensitive to the interactions of different disciplines. This technique allows the study of human movements, but only through a multidisciplinary approach, it is possible to infer relations of causation. Narrow studies focusing on specific techniques are important to develop the fundamental tools required to study movement. In recent years, significant methodological advancements have been independently made in these fields. However, to cross the borders of current science and develop consistent results any new study needs to set interdisciplinary goals. An inclusive approach merging multiple aspects would be key in targeting pharmacological or rehabilitation interventions and improving patient care as a whole.
Bidding Strategies, Financing and Control
A selection of republished corporate finance articles and book chapters that can serve as an advanced corporate finance supplementary text for courses that use no textbooks. Combining convenience and an affordable price with retypeset pages and a high-quality index, the 600 pages of volume two, "Bidding Strategies, Financing, and Corporate Control", focus on a range of special topics, ranging from theories and evidence on strategic bidding behavior (offer premiums, toeholds, bidder competition, winner's curse adjustments, and managerial overconfidence), issues arising when bidding for targets in bankruptcy auctions, effects of deal protection devices (termination agreements, poison pills), r...
Statistical Atlases and Computational Models of the Heart. Atrial Segmentation and LV Quantification Challenges
This book constitutes the thoroughly refereed post-workshop proceedings of the 9th International Workshop on Statistical Atlases and Computational Models of the Heart: Atrial Segmentation and LV Quantification Challenges, STACOM 2018, held in conjunction with MICCAI 2018, in Granada, Spain, in September 2018. The 52 revised full workshop papers were carefully reviewed and selected from 60 submissions. The topics of the workshop included: cardiac imaging and image processing, machine learning applied to cardiac imaging and image analysis, atlas construction, statistical modelling of cardiac function across different patient populations, cardiac computational physiology, model customization, atlas based functional analysis, ontological schemata for data and results, integrated functional and structural analyses, as well as the pre-clinical and clinical applicability of these methods.
