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Acute Myelogenous Leukemia in Childhood
The results of treatment for childhood acute myelogenous leukemia (AML) have improved considerably during the last ten years. This progress was demonstrated by the two consecutive multicenter studies, AML-BFM-78 and -83, in which almost identical extended multi drug regimes of che motherapy were administered for eight weeks and followed up by two years maintenance. The main difference in the second study was the addition of an eight-day intensive in duction course. Due to this new element, the relapse rate was reduced significantly. Another result of the BFM-83 study was the definition of two risk groups on the basis of standardized treatment, which has lead to a risk-adapted treatment strat...
Acute Leukemias II
Acute leukemia a quite homogenous disease failed to break through the sound barriere of when untreated reveals a substantial hetero unsatisfactory cure rates even in special sub geneity in its response to therapy. While cure groups. While new protocols including more is achieved in a certain proportion of pa effective supportive care show some increase tients other cases prove to be highly resis in the initial response rates and certain im tant. The curability is superior in acute provements in the long-term results, no ben lymphoblastic (ALL) than in acute myeloid eficial effect on the relapse rate during the (AML) leukemia and - within both type- first 1 Y2 years emerged from any of these higher in children as compared to adults. regimens. Thus, high chances for cure are The two age groups and cell types can be presently restricted to children with ALL further subdivided into prognostic groups and to lesser proportions children with by special diagnostic features. Thus, in AML and adults with ALL and AML.
Acute Leukemias VII
The 7th volume of the book series Acute Leukemias provides new updates on the biology of acute leukemias and especially the underlying genetic and molecular events. High quality contributions are provided by leading scientists and clinicians making the book an excellent overview over most recent achievements which translate into new treatment strategies and hence an improved outlook for patients suffering from acute leukemias.
Acute Leukemias VI
For 10 years the book series Acute Leukemias has been providing updates on the rapid progress being made internationally concerning this group of diseases. The fifth volume mainly addressed experimental approaches, but the present issue presents both therapeutic and prognostic aspects of the most recent results from major multicenter clinical trials. Additional chapters report new trends in leukemia cell biology,the monitoring of minimal residual disease, and secondary leukemias, as well as new antileukemic drugs, antimicrobial strategies, and the use of cytokines. The combined efforts against acute leukemias described in this book explain the recent improvements in the outcome of patients suffering from acute leukemias.
Modern Trends in Human Leukemia VIII
You see things, and sa)' why? But I dream 1hings that never were, and I say, 11'hy 110t? George Bernhard Shaw Far ahead of his time, June 1st, 1909, Alexander Maximov communicated in a lecture, given in the Charite in Berlin, the fundamental knowledge, that there exists a lymphoid hemopoetic stem cell. Alexander Friedenstein explained that during the following years, Maximov also showed that the idea of interaction between hemopoetic cells and their stroma to be one of the most significant experiences. Monoclonal antibodies, recombinant DNA technics and the improvement of tissue culture models are the major developments to improve our possibilities to clarify growth and differentiation funct...
SAP R/3 Implementation
Before use, standard ERP systems such as SAP R/3 need to be customized to meet the concrete requirements of the individual enterprise. This book provides an overview of the process models, methods, and tools offered by SAP and its partners to support this complex and time-consuming process. It begins by characterizing the foundations of the latest ERP systems from both a conceptual and technical viewpoint, whereby the most important components and functions of SAP R/3 are described. The main part of the book then goes on to present the current methods and tools for the R/3 implementation based on newer process models (roadmaps).
Generative and Component-Based Software Engineering
This book constitutes the thoroughly refereed post-proceedings of the Second International Symposium on Generative and Component-Based Software Engineering, GCSE 2000, held in Erfurt, Germany in October 2000.The twelve revised full papers presented with two invited keynote papers were carefully reviewed and selected from 29 submissions. The book offers topical sections on aspects and patterns, models and paradigms, components and architectures, and Mixin-based composition and metaprogramming.
Germany Real Estate Yearbook 2007
Germany Real Estate Yearbook 2007 contains over 250 pages of extensive information about major real estate projects in Germany, the top market players and industry trends. It also includes German decision-makers, corporate stories. a Who's Who section with personal and company profiles and the German Real Estate Index. This book is linked to its website www.germany-re.com.
