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Computational Systems Pharmacology and Toxicology
The network approaches of systems pharmacology and toxicology serve as early predictors of the most relevant screening approach to pursue both in drug discovery and development and ecotoxicological assessments. Computational approaches have the potential to improve toxicological experimental design, enable more rapid drug efficacy and safety testing and also reduce the number of animals used in experimentation. Rapid advances in availability of computing technology hold tremendous promise for advancing applied and basic science and increasing the efficiency of risk assessment. This book provides an understanding of the basic principles of computational toxicology and the current methods of p...
Sixteenth Marcel Grossmann Meeting, The: On Recent Developments In Theoretical And Experimental General Relativity, Astrophysics, And Relativistic Field Theories - Proceedings Of The Mg16 Meeting On General Relativity (In 4 Volumes)
The proceedings of MG16 give a broad view of all aspects of gravitational physics and astrophysics, from mathematical issues to recent observations and experiments. The scientific program of the meeting included 46 plenary presentations, 3 public lectures, 5 round tables and 81 parallel sessions arranged during the intense six-day online meeting. All talks were recorded and are available on the ICRANet YouTube channel at the following link: www.icranet.org/video_mg16.These proceedings are a representative sample of the very many contributions made at the meeting. They contain 383 papers, among which 14 come from the plenary sessions.The material represented in these proceedings cover the fol...
Atlas of Non-FDG PETCT in Diagnostic Oncology
Fluorodeoxyglucose (FDG) has proven benefits as a positron emission tomography (PET) radiopharmaceutical in oncology. However, it has limitations in the assessment of certain tumours, above all (but not only) prostate cancer. Therefore, several non-FDG PET radiopharmaceuticals have been introduced into the clinical arena over the last few years, and this trend will continue to spread. The use of PET/CT with different PET radiopharmaceuticals that tailor to the type of tumour and biologic process that needs to be assessed is part of personalized precision medicine. The objective of this publication is to provide a case-based way of understanding normal biodistribution, variants, and pitfalls, including several examples of typical patterns for the main indications for each of the new non-FDG PET radiopharmaceuticals. This should facilitate the interpretation of images to support accurate diagnosis. This Atlas will allow professionals interested in non-FDG PET/CT imaging to embrace the variety of oncological imaging by providing clinically relevant teaching files on the effectiveness and diagnostic quality of non-FDG-PET/CT imaging in routine applications.
Index Medicus
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
Production and Operations Management
Contents: Organisation, An Outline of the Problem, The Classic Economic Production Quality Model, The Timing of Labour Transfers in Dual Resource Constrained Systems, Procedures for Determining Relative Frequencies of Production, Materials, A Discrete Production Switching Rule for Aggregate Planning, Replanning Frequencies for Master Production Schedules, New Technology Investments in Multistage Production Systems, Simulation Approach for Determining Maintenance Crew Size for a Machine-shop A Case Study, Quality Control, Productivity and Materials Management, Product Structure Complexity and Multilevel Lot Sizing Using Alternative Costing Policies, Budgeting in Public Enterprises.
Drug Resistance in Bacteria, Fungi, Malaria, and Cancer
This book is a compilation of past and recent knowledge in the field of emerging drug resistance. The book covers major aspects of drug resistance in bacteria, fungi, malaria, and cancer.Human survival on earth is constantly threatened by disease and syndrome. From the early days, the aim of research in medicine was to find therapeutic agents that can improve the quality of human life. Although humans are dependent on natural compounds from early days their dependence of drugs increased excessively in last century. The advances in chemistry and biology have helped researchers to identify the drugs that have improved treatment of many diseases. The primary factor for treatment of these diseases is dependent on the efficacy of drugs available. The development of resistance to these drugs is one of the major hindrances. Although there are number of books available on this topic, “drug resistance” biology across kingdoms has never been discussed in a coherent way.
Surface Chemistry and Electrochemistry of Membranes
An eclectic mix of studies on chemical and electrochemical behaviour of membrane surfaces. The book looks at membranes - both organic and inorganic - from a host of different perspectives and in the context of many diverse disciplines. It explores the behaviours of both synthetic and biological membranes, employing physical, chemical and physiochemical perspectives, and blends state-of-the-art research of many disciplines into a coherent whole.
