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The Endometrium
The Endometrium is devoted to a comprehensive multi-disciplinary account of the uterine endometrium. This book is the first to define the regulatory biological interrelationships between epithelial and stromal cell phenotypes, endothelial cells, extracellular matrix and immunobiological elements. It highlights their relevance to clinical conditions
Women Leaders in School Psychology
This book offers the autobiographical reflections of prominent women school psychologists who are at or near completion of their careers. It demonstrates the varied and diverse journeys of these women in their own words. The volume examines the ways in which leading women in the field have evolved from primarily frontline service providers to full contributors at all levels of the profession. Chapters offer insights into school psychology movers and shakers and explores how many found a home in academia, where they became trainers of the next generation. In addition, chapters examine the opportunities and restraints that these women leaders confronted across the years. The book celebrates the success of these women and encourages both women and men to pursue roles in the profession. Women Leaders in School Psychology is an informative read for graduate students and scientist-practitioners as well as researchers, professors and other professionals in child and school psychology, educational policy and politics, family studies, social work, public health, clinical and developmental psychology and all related psychology, mental health, and education disciplines.
Endometriosis
This book provides an insight into the emerging trends in pathogenesis, diagnosis and management of endometriosis. Key features of the book include overviews of endometriosis; endometrial angiogenesis, stem cells involvement, immunological and hormonal aspects related to the disease pathogenesis; recent research reports on infertility, endometrial receptivity, ovarian cancer and altered gene expression associated with endometriosis; various predictive markers, and imaging modalities including MRI and ultrasound for efficient diagnosis; as well as current non-hormonal and hormonal treatment strategies This book is expected to be a valuable resource for clinicians, scientists and students who would like to have an improved understanding of endometriosis and also appreciate recent research trends associated with this disease.
Cancer
This volume reviews advances in cancer chemotherapy research over the last 10 years. Chapters written by leading experts in their field reflect a range of current medicinal chemistry approaches to small molecule drugs. Each chapter covers the drug target and biological rationale, chemotypes, clinical status and future prospects in this rapidly developing area of drug research.
Perspectives On Loss
Losses are integral to the human experience, but they sometimes unfold in subtle ways. Loss is not just about death, but can encompass a number of situations, such as those gradual losses experienced by the elderly: loss of vision, mental capacity, or hope. Intended to stimulate ideas and research in the new area of psychological aspects of loss, this sourcebook collects the writing of a set of distinguished scholars representing psychology and related fields. The author presents a case for a broadly-construed field of loss-both personal and interpersonal-that would complement other fields such as death and dying, traumatology, and stress and coping. No other volume is as comprehensive in it...
Testicular Tangrams
During the past two decades research on the testis has created a vast number of publications. New techniques, such as cell and gene clon ing, germ cell manipulation and transplantation, as well as gene ex pression, have surpassed the classical approaches that involved studies on receptor activation and endocrine, paracrine and autocrine regula tory mechanisms. Due to the expansion of this field of research it has become increasingly difficult to integrate the large number of observa tions and relate them to the physiology and pathophysiology of the tes tis. More emphasis must, therefore, be put on the integration of isolated findings and the construction of the total picture. In order to sti...
Neuroinflammation — From Bench to Bedside
Recent work has implicated inflammatory processes in the pathophysiology of a variety of neurodegenerative diseases such as Alzheimer's disease, stroke and multiple sclerosis. In this book leading experts in the field discuss molecular, in vivo and clinical aspects of neuroinflammation. It is hoped, with the wealth of research being conductied in this area, that novel therapeutic targets will be identified which will allow successful therapeutic intervention in a variety of neurodegenerative diseases.
Interferon: The Dawn of Recombinant Protein Drugs
Forty years of Interferon I wish to dedicate this short introduction to the memory of Alick Isaacs (1921-1967), and to that of Sir Christopher Andrewes (1896-1988). Let us go back more than 40 years. In 1956 Isaacs was in charge of the Wodd Influenza Centre. Andrewes was head of the division of bac teriology and virology, and deputy director of the National Institute for Medical Research in London. When researchers are faced with a seemingly new phenomenon, ex planations are easy to come by. These explanations fall into two broad categories: the phenomenon in question is either due to something or to the lack of something. I apologize for the primitive way in which I ex press this, but I am ...
Leucocyte Trafficking
An essential component of inflammation is the migration of circulating leukocytes from blood into tissues. This process is characterized by a multistep paradigm of sequential cell adhesion and activation events that lead to the extravasation of specific leukocyte subsets to different tissues in health and disease. The first step of leukocyte extravasation, the rolling of leukocytes, is primarily mediated by the interactions of selectins and their ligands. It has recently become evident that fucosyltransferases are crucial for selectin ligand synthesis, inflammation, and skin homing. This book provides an in-depth overview of the mechanisms of leukocyte trafficking and of the molecular mechanisms of selectin/selectin ligand interactions and discusses options for pharmacological intervention to treat inflammatory diseases.
