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Cry Like a Girl
The descent into madness isn't always accompanied by flashing lights and sirens. Sometimes, it sneaks up as quietly as fog... To the unknowing, Susan and Henry McFarland appear to be just another small-town couple working toward the American dream. Susan, an introverted housewife and part-time librarian is the yin to Henry's extroverted, rising-star yang. Susan has always dreamed of the perfect life: a loving husband and a home filled with children, all wrapped up in a white picket fence. But the perfect life she dreams of is rooted in the soil of a dark secret. Henry is a man's man: confident, likable, and no more than a handshake away from taking hold of the brass ring. Unknown to him, his...
Eat, Drink, and Be From Mississippi
Truely Noonan is the quintessential Southern boy made good. Like his older sister, Courtney, Truely left behind the slow, sweet life of Mississippi for jet-set San Francisco, where he earned a fortune as an Internet entrepreneur. Courtney and Truely each find happy marriages--until, as if cursed by success, those marriages start to crumble. Then their lives are interrupted by an unexpected stranger--a troubled teenager named Arnold, garrulous, charming, thuggishly dressed, and determined to move in to their world. Arnold turns their lives upside down--and in the process this unlikely trio becomes the family that each had been searching for. In the best Southern fiction tradition, Kincaid has brought us an inspiring story about finding the way home.
Dead Enemies
More than twenty years after she kills her abusive father, Sali Bloo has found happiness. A world-class runner, teacher, and recently engaged, her future looks bright until her sister is gunned down following a race. The course of her life changes when she is forced to revisit a dark past filled with lies and painful memories in order to ensure the gunman will never hurt anyone again.
Advances in Medicinal Chemistry
Volume 5 of Advances in Medicinal Chemistry contains four intriguing and detailed accounts of the close interface between synthetic chemistry, structure-activity relationships, biochemistry, and pharmacology. In Chapter 1, there is a comprehensive survey of the immunophilin area specifically focussing on neuroregenerative applications in the central nervous system. In Chapter 2, there is an overview of the development of a potent analgesic compound that works via modulation of neuronal nicotinic acetylcholine receptors. In Chapter 3, there is a description of dopamine D-2 autoreceptor partial agonists as potential therapy for the treatment of schizophrenia. In Chapter 4, there is a summary of the successful program in which potent non-peptide inhibitors of HIV protease from the AIDS virus were developed.
Children's Talk
How do children make talk "work?" Adults usually regard talk as a simple means of conveying information. Garvey explains the importance of talk to children's socialization and development and shows why talk is an integral and revealing part of the child's life that reflects important changes in thinking and social interaction.
Appetite Control
Ongoing research aims to identify additional targets and agents in order to develop drugs that meet the safety standards required for the chronic therapy of morbid obesity. This text is a comprehensive description of the mechanisms controlling food intake, and thereby energy balance, in the mammalian organism.
Did I Say That Out Loud?
'Joyous, wise, reassuring and laugh-out-loud funny. I love these two women so much.' Elizabeth Day 'The two funniest women on planet earth right now.' Dolly Alderton 'I want to be Fi and Jane when I grow up.' Clare Balding 'A book like no other. Honest and very, very funny. Some bits made me want to cheer.' Sara Cox 'If you loved the late, great Victoria Wood, then you'll love Fi and Jane too.' Red magazine Award-winning broadcasters Fi Glover and Jane Garvey don't claim to have all the answers (what was the question?), but in these hilarious and perceptive essays they take modern life by its elasticated waist and give it a brisk going over with a stiff brush. They riff together on the chuff...
Progress in Medicinal Chemistry
The success of any drug discovery project relies upon the quality of the lead that initiates the lead optimization process. What defines a 'quality lead', where these 'quality leads' come from and how one discovers them has been the subject of intense debate within the pharmaceutical industry, relies upon defining those properties that historically have led to successful drug discovery. This volume addresses these questions and specifically discusses diabetes, obesity and tuberculosis.*Presents the latest research in the field of drug discovery *Publishes on an annual basis to bring you the most innovative updates in medicinal chemistry *Available as an online resource via ScienceDirect
Criminal Law Conversations
Criminal Law Conversations provides an authoritative overview of contemporary criminal law debates in the United States. This collection of high caliber scholarly papers was assembled using an innovative and interactive method of nominations and commentary by the nation's top legal scholars. Virtually every leading scholar in the field has participated, resulting in a volume of interest to those both in and outside of the community. Criminal Law Conversations showcases the most captivating of these essays, and provides insight into the most fundamental and provocative questions of modern criminal law. * Jeffrie G. Murphy's, essay "Remorse, Apology & Mercy," was declared Recommended Reading in the Green Bag Almanac and Reader, 2010.
The Soul of Baseball
When legendary Negro League player Buck O'Neil asked Joe Posnanski how he fell in love with baseball, the renowned sports columnist was inspired by the question. He decided to spend the 2005 baseball season touring the country with the ninety-four-year-old O'Neil in hopes of rediscovering the love that first drew them to the game. The Soul of Baseball is as much the story of Buck O'Neil as it is the story of baseball. Driven by a relentless optimism and his two great passions—for America's pastime and for jazz, America's music—O'Neil played solely for love. In an era when greedy, steroid-enhanced athletes have come to characterize professional ball, Posnanski offers a salve for the damaged spirit: the uplifting life lessons of a truly extraordinary man who never missed an opportunity to enjoy and love life.
