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Ethical and Responsible Tourism
Ethical and Responsible Tourism explains the methods and practices used to manage the environmental impact of tourism on local communities and destinations. This new edition takes into account recent global events such as the Covid-19 health crisis, the impacts of the war in Ukraine on tourism in neighbouring regions and the consequences of the energy and cost of living crisis. The three core themes of the book – destination management, environmental and social aspects of ethical sustainable development and business impacts – are discussed across both topic and case study chapters, alongside explanatory editorial analysis with all chapters clearly signposted and interlinked. The case stu...
Cost allocation methods in cooperative transportation planning
Transportation, together with transportation planning for goods, provides good conditions for economic growth and is a natural part of modern society. However, transportation has negative side effects, including emissions and traffic congestion. A freight forwarder may consolidate shippers’ goods in order to reduce some of the negative side effects, thus reducing emissions and/or congestion as well as operational costs. The negative side effects as well as operational costs can be further reduced if a number of freight forwarders cooperate and consolidate their collective goods flows. Consolidation refers to the process of merging a number of the freight forwarders’ shipments of goods in...
Drug Discovery and Evaluation: Pharmacological Assays
The 4th edition of this successful reference book contains an updated selection of the most frequently used assays for reliably detecting the pharmacological effects of potential drugs. Effects covered include cardiovascular, analgesic, endocrine, psychotropic, respiratory, renal and immunomodulatory activities. Each of the more than 1,000 assays comprises a detailed protocol outlining the purpose and rationale of the method, a critical assessment of the results and their pharmacological and clinical relevance. In addition, animal models of rare diseases are described. For this 4th edition, all existing chapters have been revised and completely updated. A large number of assays were added. Sections that have been specifically enlarged include - Pharmacological assays in thrombosis and haemostasis, - Antidiabetic activity (includes completely new chapters such as Biochemical Methods in Diabetology), - Anti-atherosclerotic activity. New chapters are added such as Auditory Pharmacology, Oncology Activity, Stem Cells, Omics, Personalized Medicine, etc.
Primary Progressive Multiple Sclerosis
"Why are there no effective treatments for my condition? Why do researchers exclude patients with primary progressive multiple sclerosis from enrolling in clinical trials? Please let me know if you hear of studies that I might be allowed to enter or treatments that I could try for my condition. " Thus, in recent years, the sad lament of the patient with primary progressive MS (PPMS). This variant, often in the guise of a chronic progressive myelopathy or, less commonly, progressive cerebellar or bulbar dysfunction, usually responds poorly to corticosteroids and rarely seems to benefit to a significant degree from intensive immunosuppressive treatments. In recent years, most randomized clin i...
Social Media and Politics in Turkey
This book focuses on media and zeroes in some critical and oppositional aspects of internet usage within Turkey. It does not radically challenge some works on Turkey’s recent grand narrative but presents empirical and minor accounts to this. However, in elaborating the long history of relatively resilient and multilayered oppositional digital media networks in Turkey, this book insists that an idea of authoritarian turn may be misleading as the internet communications are exposed to repressive measures and surveillance tactics from the very beginning of the country’s recent past. While discussing from citizen journalism practices to political trolls and from Gezi Park protests to disinformation campaigns, this book pays tribute to digital activists and points out that mobilizing through digital networks can present glimmers of hope in challenging authoritarian regimes.
The X-ray Universe
Beyond the range of optical perception--and of ordinary imaginings--a new and violent universe lay undetected until the advent of space exploration. Supernovae, black holes, quasars and pulsars--these were the secrets of the highenergy world revealed when, for the first time, astronomers attached their instruments to rockets and lofted them beyond the earth's x-ray-absorbing atmosphere. The X-Ray Universe is the story of these explorations and the fantastic new science they brought into being. It is a first-hand account: Riccardo Giacconi is one of the principal pioneers of the field, and Wallace Tucker is a theorist who worked closely with him at many critical periods. The book carries the reader from the early days of the Naval Research Laboratory through the era of V-2 rocketry, Sputnik, and the birth of NASA, to the launching of the Einstein X-Ray Observatory. But this is by no means just a history. Behind the suspenseful, sometimes humorous details of human personality grappling with high technology lies a sophisticated exposition of current cosmology and astrophysics, from the rise and fall of the steady-state theory to the search for the missing mass of the universe.
Chromic Phenomena 3rd Edition
Chromic or colour related phenomena are produced in response to a chemical or physical stimulus. This new edition will update the information on all those areas where chemicals or materials interact with light to produce colour, a colour change, or luminescence especially in the imaging, analysis, lighting and display areas. The book has been restructured to show greater emphasis on applications where 'coloured' compounds are used to transfer energy or manipulate light in some way therefore reducing the details on classical dyes and pigments. In the past eight years, since the previous edition, there has been a remarkable increase in the number of papers and reviews being produced reflecting the growth of interest in this area. This ongoing research interest is matched by a large number of new technological applications gaining commercial value covering e.g. biomedical areas, energy, data storage, physical colour, bio-inspired materials and photonics. This book appeals to industrial chemists, professionals, postgraduates and as high level recommended reading for colour technology courses.
fMRI: From Nuclear Spins to Brain Functions
This volume explores the revolutionary fMRI field from basic principles to state-of-the-art research. It covers a broad spectrum of topics, including the history of fMRI's development using endogenous MR blood contrast, neurovascular coupling, pulse sequences for fMRI, quantitative fMRI; fMRI of the visual system, auditory cortex, and sensorimotor system; genetic imaging using fMRI, multimodal neuroimaging, brain bioenergetics and function and molecular-level fMRI. Comprehensive and intuitively structured, this book engages the reader with a first-person account of the development and history of the fMRI field by the authors. The subsequent sections examine the physiological basis of fMRI, the basic principles of fMRI and its applications and the latest advances of the technology, ending with a discussion of fMRI’s future. fMRI: From Nuclear Spins to Brain Function, co-edited by leading and renowned fMRI researchers Kamil Ugurbil, Kamil Uludag and Lawrence Berliner, is an ideal resource for clinicians and researchers in the fields of neuroscience, psychology and MRI physics.
Multi-scale Dynamical Processes in Space and Astrophysical Plasmas
Magnetized plasmas in the universe exhibit complex dynamical behavior over a huge range of scales. The fundamental mechanisms of energy transport, redistribution and conversion occur at multiple scales. The driving mechanisms often include energy accumulation, free-energy-excited relaxation processes, dissipation and self-organization. The plasma processes associated with energy conversion, transport and self-organization, such as magnetic reconnection, instabilities, linear and nonlinear waves, wave-particle interactions, dynamo processes, turbulence, heating, diffusion and convection represent fundamental physical effects. They demonstrate similar dynamical behavior in near-Earth space, on...
