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This book addresses the developmental origins of health and disease (DOHaD), a new medical concept that demonstrates that various adult diseases start in the fetal period. It discusses our current understanding of the molecular mechanisms of DOHaD, including gene body epigenetics and non-coding RNA, and comprehensively examines diseases such type 2 diabetes, a well known as standard DOHaD-associated disease, as well as non-alcoholic fatty liver disease, hypertension and neurodevelopmental disorders. It argues that most adult diseases start at a very early stage, such as in the fetal and neonatal periods, and that earlier prevention and intervention would result in better outcomes for adult diseases such as type 2 diabetes and cardiac disorders, which are increasing in both developed and developing countries. The book appeals to obstetricians and pediatricians, as well as physicians who treat adult patients, wanting to understand the origins of diseases.
Carbon-carbon bond forming reactions are arguably the most important processes in chemistry, as they represent key steps in the building of complex molecules from simple precursors. Among these reactions, metal-catalyzed cross-coupling reactions are extensively employed in a wide range of areas of preparative organic chemistry, ranging from the synthesis of complex natural products, to supramolecular chemistry, and materials science. In this work, a dozen internationally renowned experts and leaders in the field bring the reader up to date by documenting and critically analyzing current developments and uses of metal-catalyzed cross-coupling reactions. A particularly attractive and useful feature, that enhances the practical value of this monograph, is the inclusion of key synthetic protocols, in experimental format, chosen for broad utility and application. This practice-oriented book can offer the practitioner short cuts to ensure they remain up-to-date with the latest developments.
Safety, Reliability, Risk and Life-Cycle Performance of Structures and Infrastructures contains the plenary lectures and papers presented at the 11th International Conference on STRUCTURAL SAFETY AND RELIABILITY (ICOSSAR2013, New York, NY, USA, 16-20 June 2013). This set of a book of abstracts and searchable, full paper USBdevice is must-have literature for researchers and practitioners involved with safety, reliability, risk and life-cycle performance of structures and infrastructures.
"Preface -- Part I: Optoelectronic Sensors Technologies -- 1. Fiber and Integrated Optics Sensors: Fundamentals and Applications G. C. Righini, A. G. Mignani, I. Cacciari and M. Brenci -- 1. Introduction -- 2. Fiber and Integrated Optics: Fundamentals of Waveguiding -- 3. Waveguide Sensors: Basic Working Principle -- 4. Fiber Optic Sensors -- 5. Long-Period Optical Fiber Grating Sensors -- 6. Micro-structured Fiber Sensors -- 7. Integrated Optic Sensors -- 8. Conclusions -- References -- 2. Fiber Bragg Grating Sensors: Industrial Applications C. Ambrosino, A. Iadicicco, S. Campopiano, A. Cutolo, M. Giordano and A. Cusano -- 1. Introduction -- 2. Fiber Bragg Gratings History -- 3. Fiber Bragg...
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Most composites, particularly those made using thermoset resins, cannot be recycled or reused. As a result, most of them end up in landfills at the end of their useful life which is neither sustainable nor environment-friendly. Various laws enacted by Governments around the world and heightened global awareness about sustainability and global warming is changing this situation. Significant research is being conducted in developing and utilizing sustainable fibers and resins, mostly derived from plant, to fabricate 'Green' composites. The significant progress in the past 20 or so years in this field has led to the development of green composites with high strength or so called Advanced Green ...
The basic concept of this book is to examine the use of innovative methods augmenting traditional plant breeding towards the development of new crop varieties under different environmental conditions to achieve sustainable food production. This book consists of two volumes: Volume 1 subtitled Breeding, Biotechnology and Molecular Tools and Volume 2 subtitled Agronomic, Abiotic and Biotic Stress Traits. This is Volume 1 which consists of 21 chapters covering domestication and germplasm utilization, conventional breeding techniques and the role of biotechnology. In addition to various biotechnological applications in plant breeding, it includes functional genomics, mutations and methods of detection, and molecular markers. In vitro techniques and their applications in plant breeding are discussed with an emphasis on embryo rescue, somatic cell hybridization and somaclonal variation. Other chapters cover haploid breeding, transgenics, cryogenics and bioinformatics.