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Einstein's equations stem from General Relativity. In the context of Riemannian manifolds, an independent mathematical theory has developed around them. This is the first book which presents an overview of several striking results ensuing from the examination of Einstein’s equations in the context of Riemannian manifolds. Parts of the text can be used as an introduction to modern Riemannian geometry through topics like homogeneous spaces, submersions, or Riemannian functionals.
The biology of solid tumor metastasis has been the subject of significant scientific and clinical interest for years and while experimental evidence reveals that metastasis is not solely a random event, very little is known about the biology of metastasis originating from prostate cancer. This is in spite of the fact that the majority of prostate cancer patients die with metastatic lesions to the bone. Progress in understanding this most important aspect of prostate cancer has been hampered by the lack of suitable animal models and an inability to accurately quantify bone metastases and their responses to therapy. Over the past decade, scientists in Japan and the United States have steadily ...
Ongoing advancements in modern technology have led to significant developments in artificial intelligence. With the numerous applications available, it becomes imperative to conduct research and make further progress in this field. Artificial Intelligence: Concepts, Methodologies, Tools, and Applications provides a comprehensive overview of the latest breakthroughs and recent progress in artificial intelligence. Highlighting relevant technologies, uses, and techniques across various industries and settings, this publication is a pivotal reference source for researchers, professionals, academics, upper-level students, and practitioners interested in emerging perspectives in the field of artificial intelligence.
Her Majesty's government in the United Kingdom have decided to publish the most important documents in the Foreign Office archives relating to British foreign policy between 1919 amd 1939 in three series: the 1st ser. covering from 1919-1930, the 2d from 1930-39, the 3d from Mar. 1938 to the outbreak of the War.
This serial continues to combine regular updates of significant research in medicinal chemistry with emerging research in biological science destined to impact the discovery and development of new medicinal agents.
Marine organisms have attracted much attention as potential sources for drugs over recent years. This timely book covers the discovery, development and production of drugs from marine bacteria, fungi, microalgae, sponges and opisthobranch mollusks. A recent highlight of marine natural product research described here is the development of a painkilling drug from the venom of a sea snail. Detailed accounts are also given on a novel anticancer drug, which was first isolated from a sponge, and a potential antiosteoporotic drug of hexacoral origin. The main challenge for future new drugs from the sea remains supply, but with production by fermentation and aquaculture two promising solutions are presented. The paper dealing with the identification and culture of symbiotic bacteria responsible for the production of bioactive sponge metabolites will make valuable reading for many researchers. 'Drugs from the Sea' will be of special interest to marine ecologists, chemists, and pharmacologists involved in drug development.
Prostate cancer is the second leading cancer in men in Western society. A major concern, and an area of intensive research, involves understanding why certain prostate cancers remain localized or indolent, whereas others become aggressive and metastasize. The differences between these cancer types have profound implications for patients and physicians. Indolent d- ease, which grows very slowly, generally does not cause any problems to the patient, whereas aggressive disease requires immediate treatment, the earlier the better. At present, there are no markers that discriminate between these two entities, thus causing a dilemma for the management of patients who have recently been diagnosed. ...