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During several decades of this century, the classical physiological studies on the cardiovascular system have greatly improved our knowledge on the function of this system under normal and pathological conditions. This knowledge was the basis of the breakthrough for diagnostic techniques like the Swan-Ganz catheter, coronary arteriography, left and right heart biopsies, and invasive measurements of contractility, as well as therapeutic tools including aortocoronary bypass surgery, percutanous transluminal coronary angioplasty, and a broad field of pharmacological interventions for the whole spectrum of cardiovascular diseases, especially chronic heart failure. It was during the last decade t...
Biology and Comparative Physiology of Birds, Volume II focuses on the physiology, sexual characteristics, sensory organs, nervous system, and reproduction of birds. The selection first offers information on the central nervous system and sensory organ of birds, as well as cerebralization and related problems, brain, spinal cord, skin, taste, and olfaction. The book then ponders on equilibration, vision, and hearing of birds. Topics include regulation of somatic musculature, sensory structures and their nerves, retina, color vision, and structure of the ear. The publication examines endocrine glands, thymus, and pineal body and sex and secondary sexual characters, including genetic sex and sex differentiation, adrenal and parathyroid glands, and pituitary or hypophysis. The text also takes a look at energy metabolism, thermoregulation, body temperature, reproduction, breeding seasons and migration, and flight of birds. The selection is a vital source of information for readers interested in the physiology of birds.
Edited by a renowned scientist in the field with more than 200 high profile scientific publications to his name, this is the first book to provide a comprehensive overview of all cardiovascular hormone systems. Clearly structured, the text covers steroid and peptide hormones, amines, and arachidonic acid metabolites, as well as such others as nucleotides, nitric oxide, and acetylcholine. An essential reference for researchers working on the cardiovascular system and related diseases.
This book summarizes our current understanding about the biology and patho-biology of cardiomyocytes and depicts common techniques for the study of these cells. The book is divided into two parts; the first part provides insight into role and function of cardiomyocytes under normal conditions and describes embryogenesis and differentiation, in the second part the role of cardiomyocytes in aging and disease is discussed and cellular responses under stress conditions illustrated. Cardiomyocytes represent the main mass of the heart, and cellular malfunction directly modifies heart function leading to subsequent heart failure. As such, cardiomyocytes are causative involved in the main reasons of heart failure, such as post-infarct remodeling, hypertensive heart disease, idiopathic heart failure, and interactions with other co-morbidities such as diabetes. On the other hand, cardiomyocytes are necessarily target of therapy. Therefore, a precise understanding of cardiomyocytes biology is a pre-requisite for proper disease treatment and evidence based medicine. The book is written for cell biologists, pharmacologists and biomedical researchers specialized in cardiac and vascular biology.
Recent publications have addressed specific aspects of the endothelins, such as their roles in disease or the importance of endothelin receptors. However, in this book the entire field of endothelins is covered. This includes the pathways of endothelin production and their regulation, the local and systemic actions of endothelins, receptors for the endothelins and the signalling pathways employed, and the involvement of endothelins in a range of diseases. Attention is also paid to the development through chemistry, pharmacology and toxicology of endothelin antagonists and endothelin-converting enzyme inhibitors, with mention of all the important members of these drug classes. This leads to well-rounded discussions of the potential therapeutic benefit of endothelin inhibitors.
First published in 1985. This volume is based on a symposium, also titled Issues in the Ecological Study of Learning, that was held at the 1981 meeting of the Animal Behavior Society in Knoxville, Tennessee.
Recent advances in the field of ambient assistive living have addressed the integration of assistive technologies, e-health and personalized healthcare with the aim of enabling improved social experience as well as achieving better health outcomes. This book focuses on ambient assisted living systems and services for healthcare, a multi-disciplinary field encompassing areas such as electrical engineering, computer science, user-centered design and medicine. The book is divided into three parts: personalized healthcare monitoring technologies; ICT for ambient assistive living; and healing environments. The topics covered include sensor systems, wearable technologies, patient monitoring, home monitoring, personalized healthcare, user-centered design, ethical challenges and clinical evaluation. Providing an overview of new developments in e-health and personalized healthcare, the book will be of interest to engineers, designers and others working in the healthcare industry, and to medical practitioners.
Heart failure research is a most active area of research in academic, industrial and government-sponsored research and receives intense clinical attention. The recent recognition that inflammation is a risk factor and prognostic factor for heart disease has laid ground for preventive medicine and even anti-infective strategies in prevention and treatment of heart failure. Provides a new perspective on the etiology of cardiac failure Covers the latest developments Discusses future treatments for heart failure Ideal for researchers and clinicians
Muscle: Fundamental Biology and Mechanisms of Disease will be the first reference covering cardiac, skeletal, and smooth muscle in fundamental, basic science, translational biology, disease mechanism, and therapeutics. Currently there are no publications covering the science behind the medicine, as the majority of books are 90% clinical and 10% science. Muscle: Fundamental Biology and Mechanisms of Disease will discuss myocyte biology, also known as muscle cell biology, providing information about the science behind clinical work and therapeutics with a 90% science and 10% clinical focus. A needed resource for researchers, clinical professionals, postdocs, and graduate students, this publication will further discuss basic biology development and physiology, how processes go awry in disease states, and how the defective pathways are targeted for therapy. This book will assist both the new and experienced clinician's and researcher's need for science translation of background research into clinical applications, bridging the gap between research and clinical knowledge.
La fonction du système cardiovasculaire est d acheminer oxygène et nutriments dans divers organes et de collectionner, en retour, le gaz carbonique. Pour assurer efficacement cette fonction de nutrition et d entretien, le système cardiovasculaire a besoin de maintenir l intégrité de sa structure anatomique pour pouvoir répondre aux différentes stimulations hormonales. Nous avons donc rassemblé, dans ce livre, les données scientifiques très bien connues pour rappeler la structure du système cardiovasculaire et surtout pour souligner les principes qui gouvernent la signalisation dans les cellules cardiovasculaires. Les mécanismes comparables décrits avec d autres types de cellules ont été aussi rapportés.