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Projections
A groundbreaking tour of the human mind that illuminates the biological nature of our inner worlds and emotions, through gripping, moving—and, at times, harrowing—clinical stories “[A] scintillating and moving analysis of the human brain and emotions.”—Nature “Beautifully connects the inner feelings within all human beings to deep insights from modern psychiatry and neuroscience.”—Robert Lefkowitz, Nobel Laureate Karl Deisseroth has spent his life pursuing truths about the human mind, both as a renowned clinical psychiatrist and as a researcher creating and developing the revolutionary field of optogenetics, which uses light to help decipher the brain’s workings. In Project...
Connections
'Beautiful to read and packed with cutting-edge science' Observer 'Poetic, mind-stretching and, through it all, deeply human' Daniel Levitin Mental illness is one of the greatest causes of human suffering, its nature and origin a long-held mystery. But thanks to new science and technology, our understanding has reached a tipping point. In Connections, Professor Karl Deisseroth intertwines his own breakthrough discoveries with moving case studies from his experience as an emergency psychiatry physician, in order to tell a wider story about the origins of human emotion. Addressing some of the most timeless questions about the human condition while illuminating the roots of misunderstood disord...
Micro-, Meso- and Macro-Connectomics of the Brain
This book has brought together leading investigators who work in the new arena of brain connectomics. This includes ‘macro-connectome’ efforts to comprehensively chart long-distance pathways and functional networks; ‘micro-connectome’ efforts to identify every neuron, axon, dendrite, synapse, and glial process within restricted brain regions; and ‘meso-connectome’ efforts to systematically map both local and long-distance connections using anatomical tracers. This book highlights cutting-edge methods that can accelerate progress in elucidating static ‘hard-wired’ circuits of the brain as well as dynamic interactions that are vital for brain function. The power of connectomic approaches in characterizing abnormal circuits in the many brain disorders that afflict humankind is considered. Experts in computational neuroscience and network theory provide perspectives needed for synthesizing across different scales in space and time. Altogether, this book provides an integrated view of the challenges and opportunities in deciphering brain circuits in health and disease.
Make Life Visible
This open access book describes marked advances in imaging technology that have enabled the visualization of phenomena in ways formerly believed to be completelyimpossible. These technologies have made major contributions to the elucidation of the pathology of diseases as well as to their diagnosis and therapy. The volume presents various studies from molecular imaging to clinical imaging. It also focuses on innovative, creative, advanced research that gives full play to imaging technology inthe broad sense, while exploring cross-disciplinary areas in which individual research fields interact and pursuing the development of new techniques where they fuse together. The book is separated into ...
When Antidepressants Aren't Enough
For nearly two decades, Dr. Stuart Eisendrath has been researching and teaching the therapeutic effects of mindfulness-based cognitive therapy (MBCT) with people experiencing clinical depression. By helping them recognize that they can find relief by changing how they relate to their thoughts, Eisendrath has seen dramatic improvements in people's quality of life, as well as actual, measurable brain changes. Easily practiced breath exercises, meditations, and innovative visualizations release readers from what can often feel like the tyranny of their thoughts. Freedom of thought, feeling, and action is the life-altering result.
Generation Ex-Christian
Young people aren’t walking away from the church—they’re sprinting. According to a recent study by Ranier Research, 70 percent of youth leave church by the time they are 22 years old. Barna Group estimates that 80 percent of those reared in the church will be “disengaged” by the time they are 29 years old. Unlike earlier generations of church dropouts, these “leavers” are unlikely to seek out alternative forms of Christian community such as home churches and small groups. When they leave church, many leave the faith as well. Drawing on recent research and in-depth interviews with young leavers, Generation Ex-Christian will shine a light on this crisis and propose effective resp...
Proust Was a Neuroscientist
Is science the only path to knowledge? In this sparkling and provocative book, Jonah Lehrer explains that when it comes to understanding the brain, art got there first. Taking a group of celebrated writers, painters and composers, Lehrer shows us how artists have discovered truths about the human mind - real, tangible truths - that science is only now rediscovering. We learn, for example, how Proust first revealed the fallibility of memory; how George Eliot understood the brain's malleability; how the French chef Escoffier intuited umami (the fifth taste); how Cézanne worked out the subtleties of vision; and how Virginia Woolf pierced the mysteries of consciousness. It's a riveting tale of art trumping science again and again.
Freedom from Anxious Thoughts and Feelings
A ridiculously easy, breakthrough approach to practicing mindfulness. If you suffer from anxiety and experience racing, panicky thoughts, you need help right away. You’ve probably heard about mindfulness, and how effective it can be in easing anxiety and worry—but how do you do it, exactly? In this go-to guide, psychologist Scott Symington presents a practical, breakthrough approach called the two-screen method to help when painful thoughts feel overwhelming. Using this simplified mindfulness approach, you’ll learn to accept and redirect your thoughts and focus on your values. By using the two-screen method outlined in this book, as well as the three anchors—mindfulness skills, healt...
A Funny Thing Happened on the Way to Stockholm
The rollicking memoir from the cardiologist turned legendary scientist and winner of the Nobel Prize that revels in the joy of science and discovery. Like Richard Feynman in the field of physics, Dr. Robert Lefkowitz is also known for being a larger-than-life character: a not-immodest, often self-deprecating, always entertaining raconteur. Indeed, when he received the Nobel Prize, the press corps in Sweden covered him intensively, describing him as “the happiest Laureate.” In addition to his time as a physician, from being a "yellow beret" in the public health corps with Dr. Anthony Fauci to his time as a cardiologist, and his extraordinary transition to biochemistry, which would lead to his Nobel Prize win, Dr. Lefkowitz has ignited passion and curiosity as a fabled mentor and teacher. But it's all in a days work, as Lefkowitz reveals in A Funny Thing Happened on the Way to Stockholm, which is filled to the brim with anecdotes and energy, and gives us a glimpse into the life of one of today's leading scientists.
Creaturely Poetics
Simone Weil once wrote that "the vulnerability of precious things is beautiful because vulnerability is a mark of existence," establishing a relationship between vulnerability, beauty, and existence transcending the separation of species. Her conception of a radical ethics and aesthetics could be characterized as a new poetics of species, forcing a rethinking of the body's significance, both human and animal. Exploring the "logic of flesh" and the use of the body to mark species identity, Anat Pick reimagines a poetics that begins with the vulnerability of bodies, not the omnipotence of thought. Pick proposes a "creaturely" approach based on the shared embodiedness of humans and animals and ...
