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Projections
A groundbreaking tour of the human mind that illuminates the biological nature of our inner worlds and emotions, through gripping, moving—and, at times, harrowing—clinical stories “[A] scintillating and moving analysis of the human brain and emotions.”—Nature “Beautifully connects the inner feelings within all human beings to deep insights from modern psychiatry and neuroscience.”—Robert Lefkowitz, Nobel Laureate Karl Deisseroth has spent his life pursuing truths about the human mind, both as a renowned clinical psychiatrist and as a researcher creating and developing the revolutionary field of optogenetics, which uses light to help decipher the brain’s workings. In Project...
Connections
'Beautiful to read and packed with cutting-edge science' Observer 'Poetic, mind-stretching and, through it all, deeply human' Daniel Levitin Mental illness is one of the greatest causes of human suffering, its nature and origin a long-held mystery. But thanks to new science and technology, our understanding has reached a tipping point. In Connections, Professor Karl Deisseroth intertwines his own breakthrough discoveries with moving case studies from his experience as an emergency psychiatry physician, in order to tell a wider story about the origins of human emotion. Addressing some of the most timeless questions about the human condition while illuminating the roots of misunderstood disord...
Projections
A groundbreaking tour of the human mind that illuminates the biological nature of our inner worlds and emotions, through gripping, moving—and, at times, harrowing—clinical stories “[A] scintillating and moving analysis of the human brain and emotions.”—Nature “Beautifully connects the inner feelings within all human beings to deep insights from modern psychiatry and neuroscience.”—Robert Lefkowitz, Nobel Laureate Karl Deisseroth has spent his life pursuing truths about the human mind, both as a renowned clinical psychiatrist and as a researcher creating and developing the revolutionary field of optogenetics, which uses light to help decipher the brain’s workings. In Project...
Micro-, Meso- and Macro-Connectomics of the Brain
This book has brought together leading investigators who work in the new arena of brain connectomics. This includes ‘macro-connectome’ efforts to comprehensively chart long-distance pathways and functional networks; ‘micro-connectome’ efforts to identify every neuron, axon, dendrite, synapse, and glial process within restricted brain regions; and ‘meso-connectome’ efforts to systematically map both local and long-distance connections using anatomical tracers. This book highlights cutting-edge methods that can accelerate progress in elucidating static ‘hard-wired’ circuits of the brain as well as dynamic interactions that are vital for brain function. The power of connectomic approaches in characterizing abnormal circuits in the many brain disorders that afflict humankind is considered. Experts in computational neuroscience and network theory provide perspectives needed for synthesizing across different scales in space and time. Altogether, this book provides an integrated view of the challenges and opportunities in deciphering brain circuits in health and disease.
Make Life Visible
This open access book describes marked advances in imaging technology that have enabled the visualization of phenomena in ways formerly believed to be completelyimpossible. These technologies have made major contributions to the elucidation of the pathology of diseases as well as to their diagnosis and therapy. The volume presents various studies from molecular imaging to clinical imaging. It also focuses on innovative, creative, advanced research that gives full play to imaging technology inthe broad sense, while exploring cross-disciplinary areas in which individual research fields interact and pursuing the development of new techniques where they fuse together. The book is separated into ...
When Antidepressants Aren't Enough
For nearly two decades, Dr. Stuart Eisendrath has been researching and teaching the therapeutic effects of mindfulness-based cognitive therapy (MBCT) with people experiencing clinical depression. By helping them recognize that they can find relief by changing how they relate to their thoughts, Eisendrath has seen dramatic improvements in people's quality of life, as well as actual, measurable brain changes. Easily practiced breath exercises, meditations, and innovative visualizations release readers from what can often feel like the tyranny of their thoughts. Freedom of thought, feeling, and action is the life-altering result.
A Father's Story
Raising a Serial Killer A Father's Search for Answers In July of 1991 the country was shocked by the unfathomable crimes of serial killer Jeffrey Dahmer. But no one was more shocked than his parents. In A Father's Story, the reader is witness to the incremental unraveling of a parent's image of their child, and the "thousand different reactions" that follow. In his attempt to understand the nature of his son's psychosis, Lionel Dahmer methodically scrutinizes every possible contributing factor to his son's madness. His desperation is palpable as he searches for clues in the emotional, psychological, and genetic landscape of his son's life. Riveting and soul-wrenching, this unprecedented memoir is the confession of a father who must "confront the saddest truth a human can know-that his child has somehow crossed the line that separates the human from the monstrous."
Ageless
A guide to the biggest issue we all face. Ageing -- not cancer, not heart disease -- is the world's leading cause of death and suffering. What would the world be like if we could cure it? Living disease-free until the age of 100 is achievable within our lifetimes. In prose that is lucid and full of fascinating facts, "Ageless" introduces us to the cutting-edge research that is paving the way for this revolution. Computational biologist Andrew Steele explains what occurs biologically as we age, as well as practical ways we can slow down the process. He reveals how understanding the scientific implications of ageing could lead to the greatest discovery in the history of civilisation one that has the potential to improve billions of lives, save trillions of dollars, and transform the human condition.
Lighting Up the Brain
What if neuroscientists could look inside the human brain and watch individual brain cells send signals to one another? What if they could then control these brain cells to direct thoughts and actions? This may sound like science fiction, but it's actually a scientific revolution called optogenetics. Neuroscientists would like to use this new technology on human brains to uncover secrets about how the brain processes information and drives human behavior. Doctors hope to use optogenetics to restore sight and to treat Alzheimer's disease, Parkinson's disease, depression, and other debilitating or deadly health problems. Discover how the innovative work of leaders in the field is poised to radically transform science, medicine, and human health.
Blood and Germs
Acclaimed author Gail Jarrow, recipient of a 2019 Robert F. Sibert Honor Award, explores the science and grisly history of U.S. Civil War medicine, using actual medical cases and first-person accounts by soldiers, doctors, and nurses. The Civil War took the lives of hundreds of thousands of Americans and left countless others with disabling wounds and chronic illnesses. Bullets and artillery shells shattered soldiers' bodies, while microbes and parasites killed twice as many men as did the battles. Yet from this tragic four-year conflict came innovations that enhanced medical care in the United States. With striking detail, this nonfiction book reveals battlefield rescues, surgical techniques, medicines, and patient care, celebrating the men and women of both the North and South who volunteered to save lives.
