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Your Model Horse Collection Reference Guide 2017
Breyerfest 2017 Edition. When I had 100 models I could still remember what I owned. When I had 300 models I computerized my records - and crated the first version of this list. That was years ago. Breyer had added thousands of new models and hundreds of new molds. New (and old) companies have come and gone, or changed names. I'm always looking for more information, especially for companies and models not listed in this book. Detail start to escape me - was that the bay with 3 socks and black hooves, or the bay with 3 socks and pink hooves, of the bay with 4 socks version? There is just too much information to remember. I'm an avid collector. When I first started in the hobby, there were no books available, just box catalogs. This book is meant to be a record of YOUR collection. It is meant to be written in. You can mark if you own it or just want it. You can even write in a name for your model under the notes section. See you at Breyerfest!
Gene Vaccines
The induction of antigen-specific immune responses after in vivo transfection with expression plasmids has triggered a revolution of vaccine research. After a first hype, evoked by the fascinating options of this method, clinical studies did not reach the ambitious aims and a phase of disillusion ensued. It became obvious that Gene vaccines displayed a weaker immunogenicity in humans than had been observed in the mouse models. Meanwhile these hurdles have been overcome and gene vaccines undergo a renaissance. The present book gives an update of the “world of naked gene vaccines”, namely DNA and RNA vaccines. Its content ranges from general mechanisms, inherent immunostimulatory properties and the vast potential to modulate immune responses, to recent successful clinical studies and approved veterinary gene vaccines. Beyond the state-of-the-art of genetic immunization, the reader will be stimulated with a chapter addressing “burning questions”.
Hepatitis B Virus and Liver Disease
This book provides a comprehensive, state-of-the art review of HBV infection and liver disease. It discusses new data on basic and translational medicine, including the viral life cycle, the immunopathogenesis of virus-induced chronic hepatitis, viral and host genetic factors affecting disease progression, and the mechanism of virus-induced hepatocarcinogenesis, as well as their potential applications in daily clinical practice. The clinical aspects of chronic HBV infection are examined in chapters on the global epidemiology, efficacy of HBV vaccination, natural history, co-infections with HCV, HDV or HIV, and management of special populations including children, pregnant women and patients undergoing immunosuppressive therapy. Further, it describes the advances and perspectives in the development of novel antiviral treatments as possible cures for HBV infection. The book is a valuable resource for medical students, physicians, and researchers who are interested in managem ent of patients with chronic HBV infection and investigation of HBV infection.
Multilateral Conferences
From the UN Security Council and the European Union's Council of Ministers to obscure committees on food labelling or the scheduling of World Fairs, several thousand multilateral conferences are held each year. Why do governments deploy so much effort in these activities? What goes on behind the scenes at these meetings? How are their outcomes determined and what are the real-world consequences? Ronald A. Walker reveals the inner workings of such conferences, the result-oriented strategies that are pursued behind a façade of formal ritual and their impact on the behaviour of sovereign states.
The Science and Applications of Microbial Genomics
Over the past several decades, new scientific tools and approaches for detecting microbial species have dramatically enhanced our appreciation of the diversity and abundance of the microbiota and its dynamic interactions with the environments within which these microorganisms reside. The first bacterial genome was sequenced in 1995 and took more than 13 months of work to complete. Today, a microorganism's entire genome can be sequenced in a few days. Much as our view of the cosmos was forever altered in the 17th century with the invention of the telescope, these genomic technologies, and the observations derived from them, have fundamentally transformed our appreciation of the microbial worl...
Medications for Opioid Use Disorder Save Lives
The opioid crisis in the United States has come about because of excessive use of these drugs for both legal and illicit purposes and unprecedented levels of consequent opioid use disorder (OUD). More than 2 million people in the United States are estimated to have OUD, which is caused by prolonged use of prescription opioids, heroin, or other illicit opioids. OUD is a life-threatening condition associated with a 20-fold greater risk of early death due to overdose, infectious diseases, trauma, and suicide. Mortality related to OUD continues to escalate as this public health crisis gathers momentum across the country, with opioid overdoses killing more than 47,000 people in 2017 in the United...
Computability, Complexity, and Languages
This introductory text covers the key areas of computer science, including recursive function theory, formal languages, and automata. Additions to the second edition include: extended exercise sets, which vary in difficulty; expanded section on recursion theory; new chapters on program verification and logic programming; updated references and examples throughout.
Journalists for Hire
Dr. Udo Ulfkotte, a former editor for the German main daily newspaper, Frankfurter Allgemeine Zeitung (FAZ), has first hand knowledge of how the CIA and German Intelligence (BND) bribe journalists to write articles free of truth, facts, and with a decidedly pro-Western, pro-NATO bent or, in other words, propaganda. In his bestselling book Bought Journalists ("Gekaufte Journalisten"), Dr. Ulfkotte explains in great detail the workings of the US and NATO s propaganda campaign and how a lack of compliance with it, on the part of a journalist, can cost a career. Dr. Ulfkotte also provides a wealth of names! Journalist for Hire: How the CIA Buys the News is the English translation of Dr. Ulfkotte s bestselling book."
