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DNA Helicases and DNA Motor Proteins
In recent years, a number of groundbreaking structural and mechanistic studies deepened our understanding of helicase mechanisms and established new approaches for their analyses. Many fundamental mechanistic questions ranging from the mechanism of force generation, mechanochemical coupling to distinct mechanisms by which the same enzyme translocates on DNA removing obstacles, unwinds DNA and/or remodels nucleoprotein complexes, however, remain to be answered. It is even less understood how the helicase motors are incorporated into a wide range of genome maintenance and repair machines. The field has reached a stage when the studies of molecular mechanisms and basic biology of helicases can ...
Viral Genome Replication
This book provides the first comprehensive review of viral genome replication strategies, emphasizing not only pathways and regulation but also the structure-function, mechanism, and inhibition of proteins and enzymes required for this process.
Fresh-Start Ranch
After seeing Tessa Grant calm his storm-spooked horse, Ethan McClure is impressed. But does the new vet have what it takes to prove her mettle with Ethan's local horse-rescue group? Ethan can't deny her healing touch with animals...or her powerful effect on this rancher. But Tessa is busy trying to get her footing after leaving Kentucky to start over in this mountain town. When she learns a family secret that turns her world upside down, Tessa's ready to push everyone away. Unless Ethan can help her embrace forgiveness--and forge a path to her heart along the way.
Stories
This book is for anyone who has ever wanted to be a park ranger, forester or wildland firefighter. At the ripe old age of 30 I ask for help to grow up. You will read about problems and solutions, illness and healing. I have written this book because I believe my experiences are interesting. I believe you will be interested too.
Molecular Basis of Human Cancer
During May 21-June 1 1990, the eleventh course of the International School of Pure and Applied Biostructure, a NATO Advanced Study Institute, was held at the Ettore Majorana Center for Scientific Culture in Erice, Italy, co-sponsored by the Italian Ministry of Universities and of Scientific and Technological Research, the North Atlantic Treaty Organization, the Italian National Research Council, the Sicilian Regional Government and Technobiochip. The subject of the course was "Molecular Basis of Human Cancer" with participants selected worldwide from 15 different countries. The purpose of the course was to address, in a tutorial and structural fashion, the molecular basis of human cancer, in...
Antimutagenesis and Anticarcinogenesis Mechanisms III
Lifestyle, in any part of the world, is associated with the occurrence of major chronic diseases, including coronary heart disease, hypertension, and stroke; many distinct types of cancer; and adult onset diabetes (11,22,70,75). One important element of lifestyle is tobacco use, which appreciably increases the risk of a number of chronic diseases (21). Other lifestyle factors relate to nutritional traditions, alcohol use, and exercise (11,30,58,60,70,71). The underlying evidence is, in part, based on the evidence of specific diseases in relation to dietary habits in a given geographic region, as well as changes in such disease occurrences in migrant populations from a low risk to a high risk...
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