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Behavioral Neurobiology of GABAB Receptor Function
It has been almost forty years since Norman G. Bowery discovered and named this “non-GABAA” receptor the GABAB receptor. It has been almost ten years since the last comprehensive book presentation focused on GABAB receptors. The main goal of this book is to provide the field with a contemporary and comprehensive perspective on the GABAB receptor, its physiological relevance, and its therapeutic potential. The volume is organized into introductory and special interest sections presented by experts who study the GABAB receptor from structural, signaling, pharmacologic, physiological, pathophysiological, and therapeutic perspectives. The book aims to appeal to a broad spectrum of biomedical and clinical scientists - any scholars with an interest in GABAB receptor. The editors hope readers find this work to be thought-provoking, instructive, and informative.
Intrinsically Disordered Proteins
In this brief, Vladimir Uversky discusses the paradigm-shifting phenomenon of intrinsically disordered proteins (IDPs) and hybrid proteins containing ordered domains and functional IDP regions (IDPRs). Beginning with an introduction to the concept of protein intrinsic disorder, Uversky then goes on to describe the peculiar amino acid sequences of IDPs, their structural heterogeneity, typical functions and disorder-based binding modes. In the final sections, Uversky discusses IDPs in human diseases and as potential drug targets. This volume provides a snapshot to researchers entering the field as well as providing a current overview for more experienced scientists in related areas.
The French and American History of Michael Garoutte and His Descendants
Michael Antoine Garoutte (1750-1829) was a son of Antoine Garoutte and Lady Anne de Lascour. In 1775 Michael outfitted two ships in Marseilles, and immigrated (along with large crews of men) to New Jersey to aid the colonists in the Revolutionary War. In 1778 he married Sophia Smith at Pleasant Mills, New Jersey, and they later lived at Tuckahoe and then Pemberton, New Jersey. Descendants and relatives lived in New Jersey, New York, Ohio, Indiana, Iowa, Nebraska, Oregon and elsewhere. Includes ancestry and genealogical data to about 1600 in France.
Encyclopedia of Associations
This guide to more than 115,000 U.S. nonprofit membership organizations with interstate, state, intrastate, city or local scope and interest includes trade and professional associations, social welfare and public affairs organizations and religious, sports and hobby groups with voluntary members. Detailed entries furnish association name and complete contact and descriptive text information. This information is not duplicated anywhere in Encyclopedia of Associations. Name and keyword indexes accompany each volume.
Crossroads
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Molecular and Functional Diversity of Ion Channels and Receptors
This volume brings together an interdisciplinary group of scientists working with different neurotransmitter receptors and ion channels to discuss how the large amount of information obtained from molecular cloning can be used to advance knowledge of cell and tissue function. It documents the physiological roles of ion channels and receptors, including the functional analysis of subunit composition, role of associated proteins, functional alalysis of native and expressed channels, and physiological and pharmacological investigations of animal models in which specific channels are eliminated or altered.
New York Yankees Home Runs
The New York Yankees are synonymous with home runs. With more than 14,000 round-trippers to its credit, New York has out-homered the next most prolific franchise by more than 1,000--despite the Yankees' having been in existence for 20 fewer years. This book organizes information on the many New York home runs into detail- and summary-oriented tables. Part I covers various situational categories (e.g., grand-slam, leadoff, walk-off), special dates (Opening Day, Memorial Day, players' birthdays), and significant player and team records (Gehrig's 23 career grand-slams, five or more Yankees homers in a game). Parts II and III provide career summaries (number of seasons with 20-plus homers, by position in the batting order) and franchise totals (home runs by ballpark and opponent); and Part IV covers season-by-season totals and yearly leaders. Also included are appendices for inside-the-park and bounce home runs and home runs allowed by the Yankees.
