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Dynamics of Degeneration and Growth in Neurons
Dynamics of Degeneration and Growth in Neurons is a collection of papers presented at the International Symposium on the Dynamics of Degeneration and Growth in Neurons, held in Stockholm, Sweden, on May 16-18, 1973. Contributors explore the dynamics of degeneration and growth of central and peripheral neurons, touching on a wide range of topics such as the neurotoxic action of 6-hydroxy-dopa on central catecholamine neurons; axonal transport of proteins in growing and regenerating neurons; and collateral reinnervation in the central nervous system. Comprised of 50 chapters, this volume begins with an overview of degeneration processes in central and peripheral neurons. Results of microfluori...
Neuroendocrinology of Mood
With contributions by numerous experts
Standardizing Pharmacology: Assays and Hormones
Standardizing Pharmacology: Assays and Hormones, Volume Two in the Discoveries in Pharmacology series, presents selected articles from historic discoveries that are enhanced with commentary from contemporary scholars who present discussions on the importance of each chapter, along with an updated bibliography on the subject and contributions from a Nobel Prize winner and other pioneers in pharmacology. Academic and industry researchers in pharmacology and medicine, as well as advanced students will find this series a useful teaching tool and launch to new discoveries. Sections cover key discoveries in receptor theory, pharmacological methods and the development of hormone therapy, including ...
Extrasynaptic neurotransmission as a way of modulating multiple neuronal functions
Extrasynaptic transmission is a unifying term for a wide variety of cellular processes, in which outside of synaptic terminals transmitter substances activate extrasynaptic receptors. Whereas “synaptic transmission” immediately refers to a process occurring at nerve terminals in which the arrival of a presynaptic impulse evokes exocytosis followed by a postsynaptic response within a millisecond time scale, extrasynaptic transmission has a wide diversity of ultrastructural and therefore mechanistic associated phenomena. In comparison to synaptic, extrasynaptic exocytosis may last for seconds or even minutes, thus expanding the timing of neuronal signaling. Extrasynaptic transmission has n...
Trophic Regulation of the Basal Ganglia
Trophic Regulation of the Basal Ganglia: Focus on Dopamine Neurons examines neurotransmitters. The book first discusses the role of fibroblast growth factor-2 (FGF-2) and ganglioside GM1 and the trophic regulation of the basal ganglia. Biochemical and histochemical studies on the cellular localization of FGF-2; mapping of FGF-2 and its receptors in the basal ganglia postnatally and adulthood; and mapping of the ganglioside GM1 distribution in the basal ganglia are presented. The text also explains glucocorticoid and estrogen effects on the nigrostriatal and mesolimbic dopaminergic systems; factors associated to dopaminergic cell death in Parkinson's disease; and compensatory mechanisms at do...
Excitotoxins
None
Recent Advances in Psychiatry from Psycho-Neuro-Immunology Research: Autoimmunencephalitis, Autoimmune-Encephalopathy, Mild Encephalitis
Growing evidence derived from cerebrospinal fluid (CSF), neuropathological, imaging, genetic, and epidemiological studies link neuroinflammation and immune dysregulation to a subset of individuals with a variety of severe mental disorders (SMDs), including affective and non-affective psychotic disorders. Further, the recent discoveries of neuronal surface antibodies (NSAs) in autoimmune encephalitis (AE) presenting with diverse neuropsychiatric disorders such as psychosis and cognitive decline, among many others, provides further support to the notion that CNS autoimmunity and neuroinflammation can contribute to the neurobiology of psychiatric disturbances. Further, these immune mechanisms m...
