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Two friends have a conversation at the outset of an epic war. One of them, Arjuna, is sad and confused in the face of imminent doom; the other, K???a, decides to cheer him up and clear his doubts. Through the course of their battlefield dialogue K???a assumes the role of a mentor and inspires Arjuna, teaching him the timeless wisdom of the 'Bhagavad-g?t?.' If one wants to know about India's grand heritage, religious traditions, philosophy, and spirituality, the Bhagavad-g?t? is a good place to start. "Simple, articulate and accessible, The New Bhagavad-Gita takes a unique approach to present a modern translation of this ancient text."N R Narayana MurthyFounder-Chairman, Infosys Technologies ...
In Eicosanoid Protocols, Elias A. Lianos and a panel of hands-on experts present cutting-edge methods for the study of eicosanoids, including prostaglandins, thromboxanes, and leukotrienes. The readily reproducible methods described hereconcentrate on studying the regulation of expression and function of enzymes, particularly cyclooxygenase (and its two isoforms), phospholipase A2, and lipoxygenases involved in the synthesis of established eicosanoids. Additional chapters are devoted to the characterization and distribution of the thromboxane A2 receptor in tissues and the biological roles of novel eicosanoids. Timely and authoritative, the methods in this book will help their users in exploring the pathobiology of inflammation. Eicosanoid Protocols offers new and established researchers powerful, state-of-the-art tools to probe the regulation and function of eicosanoids.
This is the first book to extensively and exclusively cover nonconventional yeasts - all yeasts other than S. cerevisiae and S. pombe. In addition to useful background information, the author includes detailed protocols allowing the investigation of basic and applied aspects for a wide range of these organisms. Due to the increasing importance of nonconventional yeasts in biotechnological applications, this book should become the standard reference for both pure and applied scientists working in the fields of microbiology and biochemistry.
Research in the matrix metalloproteinase field began with the demonstration by Gross and Lapière, in 1962, that resorbing tadpole tail expressed an enzyme that could degrade collagen gels. These humble beginnings have led us to the elucidation of around twenty distinct vertebrate MMPs, along with a variety of homologs from such diverse organisms as sea urchin, plants, nematode worm, and bacteria. This, coupled with four known specific inhibitors of MMPs, the TIMPs, gives a complex picture. Part I of Matrix Metalloproteinase Protocols provides the reader with a selective overview of the MMP arena, and a chance to come to grips with where the field has been, where it is, and where it is going. I hope that this complements all of the methodology that comes later. Part II presents the reader with a diverse set of methods for the expression and purification of MMPs and TIMPs, bringing together the long and often hard-earned experience of a number of researchers. Part III allows the reader to detect MMPs and TIMPs at both the protein and mRNA level, whereas Part IV gives the ability to assay MMP and TIMP activities in a wide variety of circumstances.
The observation that neuropeptide Y (NPY) is the most abundant peptide present in the mammalian nervous system and the finding that it elicits the most powerful orexigenic signal have led to active investigations of the properties of the NPY family of hormones, including peptide YY (PYY) and pancreatic polypeptide (PP). Nearly two decades of research have led to the identification of several NPY receptor subtypes and the development of useful receptor selective ligands. Moreover, these investigations have imp- cated NPY in the pathophysiology of a number of diseases, including feeding disorders, seizures, memory loss, anxiety, depression, and heart failure. Vigorous efforts are therefore con...
This book shows how the Bhagavad Gītā (part of the great Indian epic — the Mahābhārata) can be approached as a powerful tool for change management and as a catalyst for organizational transformation. It presents time-tested leadership strategies drawn from the Bhagavad Gītā that are relevant for today’s leaders. This book focuses on how to harmonize the needs of the individual with the needs of society, and by extension, how to harmonize the needs of employees and the organization. It employs an inside-out leadership development approach based on Self-knowledge and Self-mastery, the two highly important areas for practicing effective Self-leadership. The Gītā is a non-sectarian spiritual text with a universal message for living a life of meaning, purpose, and contribution and for leading from our authentic self. It shows how to manage oneself, as a necessary prelude to leading others. Students and organizational leaders will learn to integrate leadership function more effectively into all aspects at the individual, team, and institutional level.
This book focuses on recent developments of Pichia pastoris as a recombinant protein production system. Highlighted topics include a discussion on the use of fermentors to grow Pichia pastoris, information on the O- and N-linked glycosylation, methods for labeling Pichia pastoris expressed proteins for structural studies, and the introduction of mutations in Pichia pastoris genes by the methods of restriction enzyme-mediated integration (REMI). Each chapter presents cutting-edge and cornerstone protocols for utilizing P. pastoris as a model recomibinant protein production system. This volume fully updates and expands upon the first edition.
Biotechnology represents a major area of research focus, and many universities are developing academic programs in the field. This guide to biomanufacturing contains carefully selected articles from Wiley's Encyclopedia of Industrial Biotechnology, Bioprocess, Bioseparation, and Cell Technology as well as new articles (80 in all,) and features the same breadth and quality of coverage and clarity of presentation found in the original. For instructors, advanced students, and those involved in regulatory compliance, this two-volume desk reference offers an accessible and comprehensive resource.
This book is based on the proceedings of the 5th ASM Conference on the Genetics and Molecular Biology of Industrial Microorganisms held in Bloomington, Indiana in October 1992. The meeting focussed on prokaryotes and lower eukaryotes, with the programme balanced between streptomyces, fungi and yeasts, and other bacteria including Escherichia coli and emerging bacterial systems. The topics of the symposia reflect major trends in research that have immediate and future industrial applications
Two friends have a conversation at the outset of an epic war. One of them, Arjuna, is sad and confused in the face of imminent doom; the other, Krishna, decides to cheer him up and clear his doubts. Through the course of their battlefield dialogue Krishna assumes the role of a mentor and inspires Arjuna, teaching him the timeless wisdom of the 'Bhagavad-Gita'. The Easy Bhagavad-Gita is so exceedingly easy that a 5000 year-old discourse feels intimate, accessible, and contemporary. And it is a great place to start if one wants to know about India's grand heritage, religion, art, culture, philosophy, and spirituality.