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Chemical Epigenetics
This book presents an authoritative review of the most significant findings about all the epigenetic targets (writers, readers, and erasers) and their implication in physiology and pathology. The book also covers the design, synthesis and biological validation of epigenetic chemical modulators, which can be useful as novel chemotherapeutic agents. Particular attention is given to the chemical mechanisms of action of these molecules and to the drug discovery prose which allows their identification. This book will appeal to students who want to know the extensive progresses made by epigenetics (targets and modulators) in the last years from the beginning, and to specialized scientists who need an instrument to quickly search and check historical and/or updated notices about epigenetics.
Functional Properties of Advanced Engineering Materials and Biomolecules
This book shows how a small toolbox of experimental techniques, physical chemistry concepts as well as quantum/classical mechanics and statistical methods can be used to understand, explain and even predict extraordinary applications of these advanced engineering materials and biomolecules. It highlights how improving the material foresight by design, including the fundamental understanding of their physical and chemical properties, can provide new technological levels in the future.
Dialogue and Learning in Mathematics Education
Dialogue and Learning in Mathematics Education is concerned with communication in mathematics class-rooms. In a series of empirical studies of project work, we follow students' inquiry cooperation as well as students' obstructions to inquiry cooperation. Both are considered important for a theory of learning mathematics. Special attention is paid to the notions of `dialogue' and `critique'. A central idea is that `dialogue' supports `critical learning of mathematics'. The link between dialogue and critique is developed further by including the notions of `intention' and `reflection'. Thus a theory of learning mathematics is developed which is resonant with critical mathematics education.
Pedro and Marques Take Stock
"[A] vibrant and punchy novel . . . Through Falero’s lovable characters, readers will meditate on violence and respectability within the death-trap of runaway capitalism. Head-on against the grim indignities of an unequal world, Falero’s poetic novel embraces humor and empathy." —Kirkus Reviews (starred review) A modern picaresque novel and vivid satire on social mobility where the lives of two Brazilian supermarket stock clerks are upturned after their small-time marijuana business takes off. In the favelas of Porto Alegre, Brazil, marijuana is hard to come by. Supermarket stock clerks Pedro and Marques spend their days unloading trucks, restocking shelves, and dreaming of a better li...
Design of Hybrid Molecules for Drug Development
Design of Hybrid Molecules for Drug Development reviews the principles, advantages, and limitations involved with designing these groundbreaking compounds. Beginning with an introduction to hybrid molecule design and background as to their need, the book goes on to explore a range of important hybrids, with hybrids containing natural products, molecules containing NO- and H2S-donors, dual-acting compounds acting as receptor ligands and enzyme inhibitors, and the design of photoresponsive drugs all discussed. Drawing on practical case studies, the hybridization of molecules for development as treatments for a number of key diseases is then outlined, including the design of hybrids for Alzheim...
Computer Supported Qualitative Research
This book includes selecting the articles accepted for presentation and discussion at WCQR2021, held on January 20th to 22nd, 2021 (Virtual Conference). The World Conference on Qualitative Research (WCQR) is an annual event that aims to bring together researchers, academics and professionals, promoting the sharing and discussion of knowledge, new perspectives, experiences and innovations on Qualitative Research. WCQR2021 featured four main application fields (Education, Health, Social Sciences, and Engineering/Technology) and seven main subjects: Rationale and Paradigms of Qualitative Research; Systematization of Approaches with Qualitative Studies; Qualitative and Mixed Methods Research; Data Analysis Types; Innovative Processes of Qualitative Data Analysis; Qualitative Research in Web Context; Qualitative Analysis with Software Support. The book is a valuable resource for everyone interested in qualitative research, emphasizing Computer-Assisted Qualitative Data Analysis Software (CAQDAS).
Performance of Manufacturing Firms in Africa
This book presents empirical analyses of manufacturing firm performance in Africa based on the World Bank Enterprise Survey and on a one-time quantitative survey conducted for the World Bank by the Center for the Study of African Economies of Oxford University.
Molecules and Medicine
Molecules and Medicine provides, for the first time ever, a completely integrated look at chemistry, biology, drug discovery, and medicine. It delves into the discovery, application, and mode of action of more than one hundred of the most significant molecules in use in modern medicine. Opening sections of the book provide a unique, clear, and concise introduction, which enables readers to understand chemical formulas.
Voices from the Love Generation
A collection of 15 interviews.
