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Psychology is of interest to academics from many fields, as well as to the thousands of academic and clinical psychologists and general public who can't help but be interested in learning more about why humans think and behave as they do. This award-winning twelve-volume reference covers every aspect of the ever-fascinating discipline of psychology and represents the most current knowledge in the field. This ten-year revision now covers discoveries based in neuroscience, clinical psychology's new interest in evidence-based practice and mindfulness, and new findings in social, developmental, and forensic psychology.
Cancer and other genetic human diseases are caused by a variety of mutations, ranging from subtle sequence changes to larger genomic rearrangements and alterations in chromosome number (aneuploidy). With contributions by reputed experts, this book aims to update the knowledge on the multiple mechanisms of genomic instability leading to human disease. Emphasis is given to the different types of genomic sequences involved in disease-related genomic rearrangements as well as to the various exogenous factors increasing the frequency of mutations. Several chapters are dedicated to the dysfunction of important cellular mechanisms like DNA repair and chromosome segregation, which may cause genomic instability and result in tumorigenesis. Important 'caretaker' genes controlling the stability of our genome have been identified through their defect in genomic instability syndromes, which are also extensively reviewed in this volume. This book provides an important update not only for investigators in biology and medicine, but also for physicians and anyone interested in the molecular basis of human disease.
The roles of mouse Y chromosome genes in spermatogenesis -- Male meiotic sex chromosome inactivation and meiotic silencing -- Insights into SRY action from sex reversal mutations -- The TSPY gene family -- Structure and function of AZFa locus in human spermatogenesis -- RBMY and DAZ in spermatogenesis -- Neurotrophic factors in the development of the postnatal male germ line -- Dickkopf-like 1-a protein unique to mammals that is associated both with formation of trophoblast stem cells and with spermatogenesis -- Antisense transcription in developing male germ cells -- The spermatogonial stem cell model -- Transplantation of germ cells and testis tissue -- Orthodox and unorthodox ways to initiate fertilization and development in mammals -- Pathogenesis of testicular germ cell tumors -- Origin of testicular germ cell neoplasia: the role of sex chromosomes.
The Social Conditions Of Ancient India Have To Be Patiently Reconstructed By Gathering Together The Data Available From Archaeology And Literature. It Is Impossible For One Individual, Even In A Lifetime, To Examine Critically All The Information At His Disposal .To The Archaeologist India Presents A Fund Of Sociological Data Covering, At Least, Five Thousand Years. And The Student Of Her Literature Finds More Elaborate And Informative Evidence In Literary Works, The Earliest Of Which Cannot Under Any Circumstances Be Dated Later Than 1000 B.C. A Careful Study Of The Facts So Available Is Absolutely Necessary If We Are To Have A Complete And Reliable Picture Of Ancient Indian Society. It Is ...
The second edition of the benchmark reference Since its first edition, this handbook has become the most influential reference work in the field of autism and related conditions. Now expanded to two volumes, this comprehensive work provides a thorough review of these disorders, drawing on findings and clinical experience from a number of related disciplines. The Second Edition covers all current treatment models, and is updated to include new methods for screening and assessment, genetic components, and school-based interventions. All chapters have been thoroughly updated; two-thirds of chapters are entirely new to this edition. VolumeTwo includes the newest, most authoritative information available on assessment, interventions, and policy ramifications surrounding pervasive developmental disorders.