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The State of European Integration
The State of European Integration provides scholars, practitioners, experts and students with a comprehensive account of the state of the European Union today. With contributions from leading scholars including Richard G. Whitman, Meltem Müftüler-Baç, Gülnur Aybet, Leila Simona Talani and Gareth Dale, the book examines the EU in a theoretically informed and empirically grounded manner. Opening with an exploration into the nature of the European Union as an international actor, it then assesses the impact of enlargement on institutions, policies and identity. The contributors investigate issues related to the degree of convergence and cohesion among members, and analyze the economic and monetary state of integration. The volume comes at a timely interval when there is a need to understand the present and future of the European Union.
Neurosteroids
Thirty years ago, the group of Baulieu and colleagues discovered that certain steroid hormones were present in higher amounts in the brain than in the plasma, and also found that suppression of circulating steroids by adrenalectomy and castration did not affect the concentration of pregnenolone, dehydroepiandrosterone and their sulfate esters in the rat brain. These seminal observations led to the concept that the brain, in very much the same way as the adrenal cortex, testis, ovary and placenta, was capable of synthesizing steroids. These brain born steroids, called neurosteroids, have been found to exert a vast array of biological activities. A number of steroidogenic enzymes have now been identified in the central nervous system by immunohistochemistry and in situ hybridization, and the neuronal and hormonal mechanisms regulating the biosynthesis of neurosteroids have been partially elucidated. The aim of this Research Topic is to celebrate three decades of research on neurosteroids by gathering a bouquet of review papers and original articles from leading scientists in the flourishing field of neurosteroids.
The Integrative Functions of The Basal Ganglia
This volume is the first comprehensive and single-authored book on the functions of the basal ganglia. The goal is to provide a new synthesis of diverse areas of research on the basal ganglia, from cellular mechanisms of synaptic transmission and plasticity to neural circuit mechanisms underlying behavior. A global theory of basal ganglia function incorporating research from the last 40 years is presented. I hope to explain for the first time how the basal ganglia generate behavior, how they contribute to learning and memory, and how impairments in basal ganglia function can lead to neurological and psychiatric disorders. Features The only single-authored book on the basal ganglia with coverage of the latest literature. Spans multiple levels of analysis, from cellular physiology to behavior. Includes coverage of clinical symptoms, encompassing neuropsychology, movement disorders, and psychiatric disorders. Discusses the role of the basal ganglia in learning and memory.
The Modern Slavery Agenda
Modern slavery, in the form of labour exploitation, domestic servitude, sexual trafficking, child labour and cannabis farming, is still growing in the UK and industrialised countries, despite the introduction of laws to try to stem it. This hugely topical book, by a team of high-profile activists and expert writers, is the first to critically assess the legislation, using evidence from across the field, and to offer strategies for improvement in policy and practice. It argues that, contrary to its claims to be ‘world-leading’, the Modern Slavery Act is inconsistent, inadequate and punitive; and that the UK government, through its labour market and immigration policies, is actually creating the conditions for slavery to be promoted.
Translating Mechanisms of Orofacial Neurological Disorder
In this volume, members of the International Translational Research Network on Orofacial Neurological Disorders and invited experts provide authoritative overviews of new aspects of motor function and sensation relating to neurological disorders in orofacial regions. Orofacial movements constitute fundamental motor patterns with essential roles in consummatory behavior, self-care, defensive and attack behaviors, vocalization and, in higher mammals, verbal as well as non-verbal communication. Clinically, dysfunction in orofacial movement is evident in numerous dental, cranio-maxillo-facial and neuropsychiatric disorders, including dysphagia, Huntington's disease, Parkinson's disease and schizophrenia. - Leading authors review state-of-the-art in their field of investigation and provide their views and perspectives for future research - Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered - All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist
Handbook of Basal Ganglia Structure and Function
Handbook of Basal Ganglia Structure and Function, Second Edition, offers an integrated overview of the structural and functional aspects of the basal ganglia, highlighting clinical relevance. The basal ganglia, a group of forebrain nuclei interconnected with the cerebral cortex, thalamus, and brainstem, are involved in numerous brain functions, such as motor control and learning, sensorimotor integration, reward, and cognition. These nuclei are essential for normal brain function and behavior, and their importance is further emphasized by the numerous and diverse disorders associated with basal ganglia dysfunction, including Parkinson's disease, Tourette's syndrome, Huntington's disease, obs...
Judging Europe’s Judges
After successive waves of EU enlargement, and pursuant to the entry into force of the Lisbon Treaty, the European Court of Justice finds itself on the brink of a new era. Both the institution itself and the broader setting within which it operates have become more heterogeneous than ever before. The issues now arriving on its docket are also often of great complexity, covering an unprecedented number of fields. The aims of this volume are to study the impact of these developments, examine the legitimacy of the Court's output in this novel context and provide an appraisal of its overall performance. In doing so, specific attention is paid to its most recent case law on four topics: the general principles of EU law, external relations, the internal market and Union citizenship. Featuring contributions by Maurice Adams, Henri de Waele, Johan Meeusen and Gert Straetmans, Koen Lenaerts, Ján Mazák and Martin Moser, Stephen Weatherill, Jukka Snell, Michael Dougan, Daniel Thym, Eileen Denza, Michal Bobek, and Joseph Weiler.
Neurobiology of Alcohol Dependence
Recent scientific advances have provided substantial information on the brain circuits and pathways relevant to various aspects of dependence. Neurobiology of Alcohol Dependence highlights the most recent data at the molecular, cellular, neurocircuitry, and behavioral levels, fostering an understanding how neuroplasticity and neuroadaptation occur, and how different neural pathways and neurocircuits contribute to dependence. - Highlights recent advances in understanding alcohol addiction from molecular, cellular, neurocircuitry, and behavioral levels - Integrates several emerging areas of research and discusses the application of novel research techniques to the understanding of alcohol dependence - Chapters authored by leaders in the field around the globe — the broadest, most expert coverage available
Handbook of Critical International Relations
Comprising a plurality of perspectives, this timely Handbook is an essential resource for understanding past and current challenges to democracy, justice, social and gender equality, identity and freedom. It shows how critical international relations (IR) theory functions as a broad-based and diverse critique of society.
The Shifting Landscape of Global Trade Governance
Takes stock of current challenges to the world trading system and develops scenarios for the future.
