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Grooming is among the most evolutionary ancient and highly represented behaviours in many animal species. It represents a significant proportion of an animal's total activity and between 30-50% of their waking hours. Recent research has demonstrated that grooming is regulated by specific brain circuits and is sensitive to stress, as well as to pharmacologic compounds and genetic manipulation, making it ideal for modelling affective disorders that arise as a function of stressful environments, such as stress and post-traumatic stress disorder. Over a series of 12 chapters that introduce and explicate the field of grooming research and its significance for the human and animal brain, this book covers the breadth of grooming animal models while simultaneously providing sufficient depth in introducing the concepts and translational approaches to grooming research. Written primarily for graduates and researchers within the neuroscientific community.
This new volume in the Handbook of Clinical Neurology presents a comprehensive review of the fundamental science and clinical treatment of psychiatric disorders. Advances in neuroscience have allowed for dramatic advances in the understanding of psychiatric disorders and treatment. Brain disorders, such as depression and schizophrenia, are the leading cause of disability worldwide. It is estimated that over 25% of the adult population in North America are diagnosed yearly with at least one mental disorder and similar results hold for Europe. Now that neurology and psychiatry agree that all mental disorders are in fact, "brain diseases," this volume provides a foundational introduction to the...
The premier guide to mobile market research The Handbook of Mobile Market Research is the first guide to focus exclusively on the use of mobile technology in market research. From a global perspective, more people own mobile phones than landlines or computers, and most people have their mobile phones with them at all times—along with their tablets, smartwatches, media players, and navigation devices. The continuous surge of mobile innovation provides unprecedented access to real-time consumer behaviour. Mobile market research allows users to reach more people, engage more people, and collect more valuable data as respondents are free to engage at their own pace, on their own time. Industry...
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This book focuses on innovative treatment options for breast cancer, including surgery, radiotherapy, systemic therapy and of course immunotherapy that is changing outcomes in some aggressive breast cancer histotypes. Subsequent chapters also address the ongoing emerging research in the screening, diagnostics, and management of all subtypes of breast cancers. All current landscapes and future perspectives in each molecular subtype: luminal, HER2-positive, and triple-negative breast cancers are discussed within the different chapters. Breast cancer is still the most common cancer and cause of cancer deaths among women worldwide. The improvement of breast cancer outcome appears to be strictly related to the validation of precise biomarkers that enable us to better select personalized approaches in breast cancer management. The closing chapters deal with the challenges of conducting research in the era of precision medicine for cancer. The book is edited and authored by leading experts in this field and will be of interest for clinicians and scientists alike.
This handy guide provides a color photograph of each Member of the House of Representatives and the Senate of the 114th Congress and details each Member's length of service, political party affiliation, and congressional district. The Pictorial Directory also contains pictures of the President, Vice President, and House and Senate officers and officials.
34 Degrees North is the latitude of Juarez and El Paso - two cities with one soul - or 17 Degrees North for each. Jack Sloan follows a trail between Juarez and Santa Fe with several stops along the way. The novel kicks off in the barrancas of the Sangre de Cristo Mountains north of Santa Fe with Jack's discovery of a satchel full of cash. Jack tells his wife Darlene about his find, and they're both sucked into the most dangerous mystery of their lives, because somewhere between Juarez and Santa Fe, a relentless killer stalks his victims and searches for his money. 17 Degrees North: A Jack Sloan Novel is the second book in the action-packed Border Wars Trilogy. Larry Seeley has a special unde...
A book that takes you inside the culture of surveillance that pits healthcare providers against their patients Doctors and pharmacists make critical decisions every day about whether to dispense opioids that alleviate pain but fuel addiction. Faced with a drug crisis that has already claimed more than a million lives, legislatures, courts, and policymakers have enlisted the help of technology in the hopes of curtailing prescriptions and preventing deaths. This book reveals how this “Trojan horse” technology embeds the logics of surveillance in the practice of medicine, forcing care providers to police their patients while undermining public trust and doing untold damage to those at risk....