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Reproductive Immunology
Discrimination of self from nonself is the major function of the immune system and understanding the mechanism(s) involved a main employer of immunologists. Hence, the age-old puzzle of why a fetus that contains a panel of major histocompatibility (MHC) antigens derived from its mother and its father is not rejected (spontaneously aborted) by lymphocytes from its mother who should theoretically recognize foreign MHC molecules from the father has remained of great interest. This dilemma has enticed immunologists and developmental biologists for many years. This volume was created to present the information currently on hand in this subject to the scientific public. The guest editor, Professor...
Advances in Immunology
Advances in Immunology
Current Catalog
First multi-year cumulation covers six years: 1965-70.
Perinatal Pathology
None
The Immunology of the Fetus
First published in 1989, this book provides information on the diagnosis and treatment of neonatal immunodeficiencies. It includes a survey on the "riddle of the fetal allograft". Also discussed in the text are Ontogeny, immunological aspects of differentiation, and treatment of spontaneous abortion. This book is useful to predoctoral students, researchers in obstetrics, animal husbandry, and reproductive immunology.
Advances in Immunology
KEY TOPICS: Ig A Deficiency The Role of Cellular Immunity in Protection against HIV Infection Mouse Mammary Tumour Virus: Immunological Interplays between Virus and Host The Transporter Associated with Antigen Processing NF-kB in cytokine gene expression NF-kB as a target for immunosuppressive and anti-inflammatory molecules Key Features* A Deficiency* The Role of Cellular Immunity in Protection against HIV Infection* Mouse Mammary Tumor Virus: Immunological Interplays between Virus and Host* The Transporter Associated with Antigen Processing* NF-kB in cytokine gene expression* NF-kB as a target for immunosuppressive and anti-inflammatory molecules
Origin and Evolution of the Vertebrate Immune System
The comparative approach to immunology can be traced to the era of Pasteur and Metchnikov in which observations regarding foreign recognition in invertebrates was a factor in the develop ment of the principal concepts that created the foundation of what now is the broad field of immunology. With each major experimental and conceptual breakthrough, the classical, albeit essential, question has been asked "are the immune systems of phylogenetically primitive vertebrates and invertebrates similar to that of mammals?" Somewhat surprisingly for the jawed verte brates, the general answer has been a qualified form of "yes", whereas for agnathans and invertebrate phyla it has been "no" so far. The a...
Protein Modules in Signal Transduction
This volume in the series Current Topics in Microbiology and Immunology focuses on protein modules in signal transduction. Topics covered include: functions of SH2 and SH3 domains; structure and function of LIM domains; and the IRS-signalling system.
