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The Rise of Virulence and Antibiotic Resistance in Staphylococcus aureus
Staphylococcus aureus S. aureus is a growing issue both within hospitals and community because of its virulence determinants and the continuing emergence of new strains resistant to antimicrobiotics. In this book, we present the state of the art of S. aureus virulence mechanisms and antibiotic-resistance profiles, providing an unprecedented and comprehensive collection of up-to-date research about the evolution, dissemination, and mechanisms of different staphylococcal antimicrobial resistance patterns alongside bacterial virulence determinants and their impact in the medical field. We include several review chapters to allow readers to better understand the mechanisms of methicillin resistance, glycopeptide resistance, and horizontal gene transfer and the effects of alterations in S. aureus membranes and cell walls on drug resistance. In addition, we include chapters dedicated to unveiling S. aureus pathogenicity with the most current research available on S. aureus exfoliative toxins, enterotoxins, surface proteins, biofilm, and defensive responses of S. aureus to antibiotic treatment.
Frontiers in Staphylococcus aureus
Staphylococcus was first recognized as a human pathogen in 1880 and was named for its grape cluster-like appearance. In 1884, Staphylococcus aureus was identified and named for its vibrant golden color, which was later found to be the result of golden toxin production. Here, experts examine in-depth patterns of S. aureus colonization and exposures in humans, mammals, and birds that have led to the development of various clinical diseases. The mode of transmission of S. aureus and different methods for its detection in different samples are defined. Conventional antibiotic options to treat this aggressive, multifaceted, and readily adaptable pathogen are becoming limited. Alternative, novel chemotherapeutics to target S. aureus are discussed in the pages within, including herbal medicines, bee products, and modes of delivery.
Tobacco Dependence
This book is a guide to pharmacotherapy treatment of tobacco dependence. The 2020 American Thoracic Society clinical practice guidelines on treating tobacco dependence serves as the cornerstone for this work with its robust discussion of recommended treatment options and how to tailor treatment to specific patient populations. Tobacco dependence remains a major health concern for many adults and given the dramatic increase of youth electronic cigarette use, clinicians need a singular resource to treat these different populations. This book addresses that by following the three main points of how to best address the adverse impact of tobacco use on public health: 1) prevent initiation of toba...
Electronic Cigarettes and Vape Devices
Electronic cigarettes (E-cigarettes), also known as vape devices or by trade names such as JUUL, are handheld devices that aerosolize liquid commonly containing nicotine, humectants and flavorings. Used by 1 in 5 high school students in 2020, they are the most common tobacco product used by youth. E-cigarette use has been associated with a variety of health issues such as nicotine addiction, e-cigarette or vaping associated lung illness (EVALI), seizures, and increased risk of cardiovascular disease. This first-of-its-kind book begins with an introduction and background on the historical context of tobacco products. The next chapters provide an overview of the e-cigarette landscape and revie...
Manual of Clinical Problems in Pulmonary Medicine
Stay current with the latest information on the diagnosis and management of pulmonary disorders with Manual of Clinical Problems in Pulmonary Medicine, 7e. Drawing on the expertise of a stellar team of renowned experts in the field, this updated pocket reference provides concise coverage of all aspects of pulmonary disorders, including pathophysiology, differential diagnoses, and the latest evidence-based treatments for pulmonary illness. Featuring a spiral binding, compact size, and concise entries, this reference is ideal for bedside use and is portable enough to take along as you move between home, clinic, and hospital. “Well worth reading cover to cover and will serve as an excellent r...
Manual for Pulmonary and Critical Care Medicine E-Book
Clinical Practice Manual for Pulmonary and Critical Care Medicine, by Judd W. Landsberg, MD, is a unique point-of-care manual that provides essential information on managing inpatients and outpatients with common, serious respiratory and internal medicine presentation and problems. Easy-to-follow diagnostic and therapeutic algorithms are accompanied by case-based illustrations encountered on a daily basis by attendings, fellows, residents, and students. The bulleted format, concise approach, and familiar examples provide a framework for effective teaching, learning, and patient care. - Identifies common but important misconceptions that are regularly encountered in pulmonary and critical car...
WHO Study Group on Tobacco Product Regulation. Report on the scientific basis of tobacco product regulation
This eighth report of the Study Group addresses electronic nicotine delivery system (ENDS), electronic non-nicotine delivery system (ENNDS) and heated tobacco product (HTPs); however, it does not cover all aspects of these products, because many of the papers were written to meet the request of COP8, which was to review understanding on novel and emerging tobacco products (FCTC/COP8). Continued research is necessary on these products; the Study Group will cover other products of interest (including traditional products, such as waterpipes, cigarettes and smokeless tobacco) in its next report, guided by countries’ regulatory requirements and pertinent issues in tobacco product regulation. This will ensure continued, timely technical support to all countries and address all products, recognizing that their availability depends on the jurisdiction.
The Multiple Inert Gas Elimination Technique (MIGET)
The Multiple Inert Gas Elimination Technique (MIGET) is a complex methodology involving specialized gas chromatography and sophisticated mathematics developed in the early 1970’s. Essentially, nobody possesses knowledge of all its elements except for its original developers, and while some practical and theoretical aspects have been published over the years, none have included the level of detail that would be necessary for a potential user to adopt and understand the technique easily. This book is unique in providing a highly detailed, comprehensive technical description of the theory and practice underlying the MIGET to help potential users set up the method and solve problems they may e...
