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The Immune Self is the first extended philosophical critique of immunology.
History, Wild Mice, and Genetics, the first volume in the four volume set, The Mouse in Biomedical Research, provides information about the history, biology and genomics of the laboratory mouse (Mus musculus), as well as basic information on maintenance and use of mouse stocks. Mouse origins and relationships are covered in chapters on history, evolutionary taxonomy and wild mice. Genetics and genomics of the mouse are covered in chapters on genetic nomenclature, gene mapping, cytogenetics and the molecular organization of the mouse genome. Maintenance of laboratory mice is described in chapters on breeding systems for various types of strains and stocks and genetic monitoring. Use of the mouse as a model system for basic biomedical research is described in chapters on chemical mutagenesis, gene trapping, pharmacogenetics and embryo manipulation. The information in Volume 1 serves as a primer for scientists new to the field of mouse research.
In this accessible history of science and medicine, Marcus exposes the complex story of the efforts made from 1875 through 1915 to first conquer and, failing that, to control cancer--a dual approach that remains in force to this day. He reveals the messiness of real-time scientific research, tracing the repeated lurches of promise, discoveries of hope, and the inevitable despair that always followed. Other barriers existed to the research, such as inconsistency in test standards and inter-laboratory competition and mistrust. Researchers approached cancer from such disparate specialties as clinical medicine, zoology, botany, chemistry, nutrition, bacteriology, pathology, and microbiology. Although they came from diverse fields, each steadfastly maintained that cancer operated in an analogous fashion to other bacteriological diseases.
Papers --Japanese Medicine in Manchuria : The South Manchuria Medical College /John Z. and Akiko K. Bowers --Physiology, General Education and the Antivivisection Movement /Lloyd G. Stevenson --Leo Loeb's Role in Development of Tissue Culture /Lewis Phillip Rubin --Pflüger's Nerve Reflex Theory of Menstruation : The Product of Analogy, Teleology and Neurophysiology /Hans H. Simmer --Amy Lowell and the Death of John Keats /Saul Jarcho --Contributors to this Issue --Papers --Les Handicapés et la Révolution Française Aspects de Médecine Sociale /Dora B. Weiner --The Child Model (or the Model Child?) of the Late Nineteenth Century in Urban America /Deborah Dwork --Hideyo Noguchi (1876-1928)...
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Establishing endocrinology as a distinct medical specialty was no easy task. This engaging volume chronicles the journey through the stories of the men –and occasional women—who shaped the specialty through the ages. In 108 brief chapters, A Biographical History of Endocrinology illuminates the progress of endocrinology from Hippocrates to the modern day. The author highlights important leaders and their contributions to the field, including these early pioneers: Kos and Alexandria, and the first human anatomy Bartolomeo Eustachi and the adrenal gland Richard Lower and the pituitary gland Thomas Addison and adrenal insufficiency Franz Leydig and testosterone secreting cells Wiliam Stewar...
A History of Organ Transplantation is a comprehensive and ambitious exploration of transplant surgery—which, surprisingly, is one of the longest continuous medical endeavors in history. Moreover, no other medical enterprise has had so many multiple interactions with other fields, including biology, ethics, law, government, and technology. Exploring the medical, scientific, and surgical events that led to modern transplant techniques, Hamilton argues that progress in successful transplantation required a unique combination of multiple methods, bold surgical empiricism, and major immunological insights in order for surgeons to develop an understanding of the body's most complex and mysteriou...
From 1928 to 1972, the Alberta Sexual Sterilization Act, Canada’s lengthiest eugenic policy, shaped social discourses and medical practice in the province. Sterilization programs—particularly involuntary sterilization programs—were responding both nationally and internationally to social anxieties produced by the perceived connection between mental degeneration and heredity. Psychiatry and the Legacies of Eugenics illustrates how the emerging field of psychiatry and its concerns about inheritable conditions was heavily influenced by eugenic thought and contributed to the longevity of sterilization practices in Western Canada. Using institutional case studies, biographical accounts, and...