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Lysosomal Storage Disorders
The knowledge of lysosomal biology and the consequences of its dysfunction have increased dramatically in the past 60 years. This book describes the nature of the lysosomal dysfunction and diseases as well as potential future treatments and therapies. Disease specific chapters provide thorough reviews of the clinical features of lysosomal storage disorders, their molecular basis and the commercial or experimental therapeutic approaches sought in this area. This is an invaluable resource for researchers in biochemical and molecular genetics, enzyme therapy, and gene transfer.
Microorganisms and Mental Health
This volume contains up-to-date contributions written by leading experts in the role played by various microorganisms in psychiatric and neurological illness. The initial chapters present an evolutionary framework for the impact of microorganisms on behavior. This is followed by historical and epidemiological perspectives of the role of viruses in psychiatric illness. Subsequent chapters focus on different classes of microorganisms and psychiatric illnesses and emphasize diverse research approaches ranging from preclinical models to therapeutic interventions.
Mammalian Artificial Chromosomes
In 1996, we organized a workshop, inter alia, at the National Research Co- cil in Milan under the generous sponsorship of the European Science Foun- tion. On that occasion, a small group of investigators convened from many countries and presented early evidence of the possibility of assembling basic units of mammalian chromosomes into artificial constructs (or, indeed, red- ing the relevant components to more manageable dimensions and defined c- stitution). Progress in the following years has been slow but steady. Many scientists who took part in the workshop have since been engaged in active and prod- tive research. It goes to the credit of Humana Press to have realized the need for a book ...
Immuno-Psychiatry
This book presents a thorough and critical review of current knowledge on the role of immunology in major psychiatric disorders and its potential applications. The opening chapters offer general information on the immune influence of the brain to provide readers with a better understanding of the end of immune privilege. The book then examines possible underlying mechanisms leading to psychiatric disorders, from early infections to pro-inflammatory markers, stress, and immune genetic background, linking etiology and psychiatry. The third section describes each disorder (ie autism, schizophrenia, bipolar disorder, depression...) with an overview of underlying immune dysfunctions. Lastly, the ...
The Notebooks of Leonardo Da Vinci
More than fifteen hundred extracts containing the Renaissance genius' maxims, prophecies, fables, letters, and brilliant observations in architecture, painting, physiology, geography, and other fields
Immuno-Psychiatry
This book presents a thorough and critical review of current knowledge on the role of immunology in major psychiatric disorders and its potential applications. The opening chapters offer general information on the immune influence of the brain to provide readers with a better understanding of the end of immune privilege. The book then examines possible underlying mechanisms leading to psychiatric disorders, from early infections to pro-inflammatory markers, stress, and immune genetic background, linking etiology and psychiatry. The third section describes each disorder (ie autism, schizophrenia, bipolar disorder, depression...) with an overview of underlying immune dysfunctions. Lastly, the ...
iPSCs for Studying Infectious Diseases
The series Advances in Stem Cell Biology is a timely and expansive collection of comprehensive information and new discoveries in the field of stem cell biology. iPSCs for Studying Infectious Diseases, Volume 8 addresses how important induced pluripotent stems cells are and how can they can help treat certain infectious diseases. Somatic cells can be reprogrammed into induced pluripotent stem cells by the expression of specific transcription factors. These cells have been transforming biomedical research over the last 15 years. This volume will address the advances in research of how induced pluripotent stem cells are being used for treatment of different infectious diseases, such as corona ...
Leonardo da Vinci's Paragone
Leonardo da Vinci's arguments for the supremacy of painting over the arts of poetry, music, and sculpture address issues that have been relevant to debates over the nature of representation since the time Plato discussed imitation until today, maintains Claire Farago in this wide-ranging critical analysis of the first important modern contribution to the comparison of the arts. This study systematically examines 46 passages compiled in the mid-sixteenth century from eighteen of Leonardo's notebooks and their relationship to the artist's holograph writings on painting, providing a critical transcription newly made from the Codex Vaticanus Urbinas 1270 and a new English translation with extensive notes that take into account Leonardo's scientific terminology, the highly contrived form of his rhetorical argumentation, and the role played by his original editors.
DNA and Cell Biology
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Cent'anni di psicoanalisi
Perché in cent'anni la psicoanalisi non è riuscita a curare il malessere dell'uomo, non ci ha reso più felici, non ha creato un mondo migliore? A oltre un secolo dalla nascita della terapia psicoanalitica, uno dei grandi filosofi e psicologi del Novecento e uno scrittore dialogano, interrogandosi sugli obiettivi raggiunti da questa disciplina e ne tracciano un bilancio. Sempre più persone infatti vi si rivolgono per contrastare un crescente malessere, eppure nella società occidentale continuano a dilagare nevrosi, paure, infelicità. La psicoterapia ha dunque fallito? E soprattutto, come si può intervenire oggi perché possa tornare efficace? Forse l'errore è stato concentrarsi esclus...
