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Tumor Microenvironment
  • Language: en
  • Pages: 548

Tumor Microenvironment

This volume discusses novel concepts in cancer biology, focusing on different factors that affect the tumor microenvironment. Topics covered include sex-based differences in the tumor microenironment, dormancy in the tumor microenvironment, the influence of obesity on the tumor microenvironment, and much more. Taken alongside its companion volumes, Tumor Microenvironment: Novel Concepts covers the latest research on various aspects of the tumor microenvironment, as well as future directions. Useful for introducing the newer generation of researchers to the history of how scientists studied the tumor microenvironment as well as how this knowledge is currently applied for cancer treatments, it will be essential reading for advanced cell biology and cancer biology students, as well as researchers seeking an update on research on the tumor microenvironment.

Recent Advances in iPSC-Derived Cell Types
  • Language: en
  • Pages: 282

Recent Advances in iPSC-Derived Cell Types

The series Advances in Stem Cell Biology is a timely and expansive collection of comprehensive information and new discoveries in the field of stem cell biology.Recent Advances in iPSC-derived Cell Types, Volume 4 addresses how different cell types can be derived from induced pluripotent stem cells.Somatic cells can be reprogrammed into Induced pluripotent stem cells by the expression of specific transcription factors. These cells are transforming biomedical research in the last 15 years. The volume teaches readers about current advances in the field. This book describes the use of induced pluripotent stem cells to form different cell types which can be used in cell therapy as well as to mod...

Current Progress in IPSC-derived Cell Types
  • Language: en
  • Pages: 336

Current Progress in IPSC-derived Cell Types

  • Type: Book
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  • Published: 2021-06-09
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  • Publisher: Elsevier

"Current Progress in iPSC-derived Cell Types, Volume 10 addresses how induced pluripotent stem cells (iPSCs) can be differentiated into different cell types. Somatic cells can be reprogrammed into iPSCs by the expression of specific transcription factors. These cells have been transforming biomedical research over the last 15 years. This volume will address the advances in how a variety of cell types can be derived from iPSCs for their use in disease modeling and regenerative medicine"--Page 4 of cover.

Stem Cell Microenvironments and Beyond
  • Language: en
  • Pages: 276

Stem Cell Microenvironments and Beyond

  • Type: Book
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  • Published: 2017-12-03
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  • Publisher: Springer

This book discusses the main stem cell niches under distinct pathophysiological conditions. The role of tissue microenvironments in stem cell regulation, as well as modern methodologies and new techniques for the identification and characterization of stem cell niches, are discussed by leading experts in the field. Chapters describe the major components of various stem cell microenvironments, such as cellular components, soluble factors, cell-cell interactions, extra-cellular matrix proteins, and physical forces. Stem Cell Microenvironments and Beyond is part of the highly successful Advances in Experimental Medicine and Biology series. It is essential reading for graduate students and researchers in the field of stem cells or cell biology as well as clinicians.

Stem Cells Heterogeneity - Novel Concepts
  • Language: en
  • Pages: 233

Stem Cells Heterogeneity - Novel Concepts

  • Type: Book
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  • Published: 2019-04-23
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  • Publisher: Springer

This book presents a comprehensive discussion on the novel concepts in stem cell heterogeneity, from pluripotent stem cells to human mesenchymal stem cells, adult and cancer stem cells of the thyroid, sarcoma, and more. Thus, Stem Cell Heterogeneity - Novel Concepts starts from a timely update on the current information on stem cells heterogeneity in various tissues and discusses new concepts and future directions. It also provides a solid foundation of the history of stem cells from specific tissues and the current applications of this knowledge in regenerative medicine. When taken as a whole, alongside its companion volumes Stem Cells Heterogeneity in Different Organs, and Stem Cells Heterogeneity in Cancer, these three books present a comprehensive reference on stem cell heterogeneity in various tissues and current and future applications for regenerative medicine. It is essential reading for advanced cell biology students as well as researchers in stem cells and clinicians.

Novel Concepts in IPSC Disease Modeling
  • Language: en
  • Pages: 336

Novel Concepts in IPSC Disease Modeling

  • Type: Book
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  • Published: 2022-01-19
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  • Publisher: Elsevier

"[A]ddresses how induced pluripotent stem cells can be used to model various diseases. Somatic cells are reprogrammed into induced pluripotent stem cells by the expression of specific transcription factors. These cells are transforming biomedical research in the last 15 years. This volume teaches readers about current advances in the field. This book describes the use of induced pluripotent stem cells to model several diseases in vitro, enabling us to study the cellular and molecular mechanisms involved in different pathologies. Further insights into these mechanisms will have important implications for our understanding of disease appearance, development, and progression. In recent years, r...

Tumor Microenvironments in Organs
  • Language: en
  • Pages: 155

Tumor Microenvironments in Organs

Revealing essential roles of the tumor microenvironment in cancer progression, this book provides a comprehensive overview of the latest research on the tumor microenvironment in over thirty human organs, including the parathyroid gland, heart, intestine, testicles, and more. Taken alongside its companion volumes, these books update us on what we know about the different aspects of the tumor microenvironments in distinct organs as well as future directions. Tumor Microenvironments in Organs: From the Brain to the Skin – Part A is essential reading for advanced cell biology and cancer biology students as well as researchers seeking an update on research in the tumor microenvironment.

Pericyte Biology in Different Organs
  • Language: en
  • Pages: 283

Pericyte Biology in Different Organs

  • Type: Book
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  • Published: 2019-04-01
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  • Publisher: Springer

The present book is an attempt to describe the most recent developments in the area of pericyte biology which is one of the emergent hot topics in the field of molecular and cellular biology today. Here, we present a selected collection of thirteen detailed chapters on what we know so far about pericytes in distinct organs in physiological and pathological conditions. Further, it provides an update on the most novel functions attributed to these cells and will introduce a newer generation of researchers and scientists to the importance of these cells, ranging from their discovery in different organs through current state-of-the-science. It will be invaluable for both advanced cell biology st...

Tumor Microenvironment
  • Language: en
  • Pages: 153

Tumor Microenvironment

Revealing essential roles of the tumor microenvironment in cancer progression, this book focuses on the role of hematopoietic components of the tumor microenvironment. Further, it teaches readers about the roles of distinct constituents of the tumor microenvironment and how they affect cancer development. Topics include neutrophils, basophils, T helper cells, cytotoxic lymphocytes, fibrocytes, and myeloid-derived suppressor cells, and more. Taken alongside its companion volumes, these books update us on what we know about various aspects of the tumor microenvironment as well as future directions. Tumor Microenvironment: Hematopoietic Cells – Part A is essential reading for advanced cell biology and cancer biology students as well as researchers seeking an update on research in the tumor microenvironment.

Life, Death, and Eternity
  • Language: en
  • Pages: 177

Life, Death, and Eternity

  • Type: Book
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  • Published: 2024-05-16
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  • Publisher: Balboa Press

Although uncertainty is an inherent part of life, it is universally agreed that death, as the end of an individual’s current known life, is inevitable. Yet extensive research and careful analysis of scientific literature seems to show that our existence may continue beyond what we currently understand. It is possible that we will transition through different stages, adapting to new environments and circumstances. Therefore, the future holds the potential for exciting discoveries and a deeper understanding of what it means to be alive. In an academic presentation, consultant geriatrician Dr. Kawa Amin delves into the fascinating realm of immortality and the attempts throughout history to ov...