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List of members separately paged, bound at end of [v. 18-19] 1867/68-1868/69; also, various brief reports, papers, etc., separately paged, bound at end of [v. 16-19, 22-24] 1965/66-1868/69, 1871/72-1873/74.
Since the first concepts of gene therapy were formulated, the hemopoietic system has been considered the most natural first target tissue for genetic manipulation. The reasons for this include the fact that a very large number of inherited disorders (including some of the most common disorders, such as the hemoglobinopathies) are disorders of the hemopoietic system, and the large amount of experience in hematopoietic transplantation biology. The consequence of this resulted in the first clinical trial of gene therapy in 1989, where two children suffering from severe combined immune deficiency (ADA-SCID) were transplanted with T-cells express ing adenosine deaminase (the defective enzyme in p...
Nineteen scientists, doctors and philosophers share their perspective on what is arguably the most significant scientific development that humanity has ever faced - the eradication of aging and mortality. This anthology is both a gentle introduction to the multitude of cutting-edge scientific developments, and a thoughtful, multidisciplinary discussion of the ethics, politics and philosophy behind the scientific conquest of aging.
This text brings together the current data previously separated. It combines information on gene therapy technologies and the attendant regulatory requirements for gene therapy, products and procedures.