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The Pigmentary System
The most comprehensive and integrated book on pigmentation The Pigmentary System, Second Edition, gathers into one convenient, all-inclusive volume a wealth of information about the science of pigmentation and all the common and rare clinical disorders that affect skin color. The two parts, physiology (science) and pathophysiology (clinical disorders), are complementary and annotated so that those reading one part can easily refer to relevant sections in the other. For the clinician interested in common or rare pigment disorders or the principles of teaching about such disorders, this book provides an immediate and complete resource on the biologic bases for these disorders. For the scientis...
Targeting Indoleamine 2,3-dioxygenases and Tryptophan Dioxygenase for Cancer Immunotherapy
Topic Editor Dr. Alexander J. Muller receives financial support by IO Biotech company. All other Topic Editors declare no competing interests with regards to the Research Topic subject.
CARMA Proteins: Playing a Hand of Four CARDs
Some twenty years ago, the search began for B-cell lymphoma (BCL)-10 binding partners that connect via homophilic interaction with its N-terminal caspase recruitment domain (CARD) to induce nuclear factor-kappa B (NF-κB) activation. This effort led first to the identification of the protein CARD9. Soon afterwards, similar searches identified CARD10 (aka CARMA3), CARD11 (aka CARMA1) and CARD14 (aka CARMA2), as further BCL10 interactors. These discoveries paved the way for landmark progress in our understanding of NF-κB activation pathways downstream of several cell surface receptors on multiple cell types, focused particularly on antigen receptors on lymphocytes. An additional binding partn...
Biophysical Methods for Diagnosing Human Tissue Anomalies
Medical diagnosis of tissue anomalies, particularly cancer, is often limited by the constraints of current imaging technologies. This book introduces two approaches to address this issue: the imaging and the non-imaging methods. In the imaging category, the book unveils a pioneering technique based on radio tomosynthesis. Initially proven effective in detecting breast anomalies, this imaging method is now under evaluation for its potential in identifying brain anomalies. For non-imaging diagnostics, it delves into Fourier-transform infrared spectroscopy (FTIR), a technique known for its speed and reliability. The book demonstrates its successful application in diagnosing a range of cancers, including oral, uterine, ovarian, gastrointestinal, colorectal, and skin cancers. Furthermore, it explores its utility in predicting embryo quality and assessing pressure injuries. To augment these methods, the book employs machine learning algorithms, evaluating their efficacy in creating discriminative models for tissue anomalies.
Fitzpatrick's Dermatology in General Medicine, Eighth Edition, 2 Volume set
The landmark dermatology text that bridges the gap between science and clinical medicine—updated for today’s practice Generations of clinicians, skin biologists, residents, and educators have acclaimed Fitzpatrick’s as the most authoritative and complete guide to dermatologic basic sciences, histopathology, diagnosis, and treatment. Edition after edition, it reflects the latest insights into skin diseases and skin biology—and their practical relevance to general internal medicine—while covering the scientific foundations of the specialty. This classic yet cutting-edge text is supported by the expert insights of more than 500 internationally respected contributors, and it covers eve...
Fitzpatrick's Dermatology In General Medicine, Seventh Edition
The must-have reference in dermatology--now completely revised and updated in full color! In no other source but Fitzpatrick's can you find the most comprehensive, current, and authoritative coverage of the entire spectrum of dermatologic science, diagnosis, treatment, and management. Now in a more accessible format, with everything you need to know about skin, skin symptoms, and skin diseases right at your fingertips -- from the basic science of the skin as an immunoprotective organ -- to the day-to-day clinical issues of managing skin diseases like psoriasis, acne, and skin cancer. Encyclopedic in scope, yet skillfully edited so that it's easy to read and use every day, this unsurpassed re...
Fitzpatrick's Dermatology, Ninth Edition, 2-Volume Set (EBOOK)
The gold-standard text in dermatology – completely updated for today’s practice by an all-new editorial board Encyclopedic in scope, yet skillfully edited to make it easy to read and understand, this trusted classic delivers everything clinicians need to know about skin, skin symptoms, and skin diseases. Presented in full color, Fitzpatrick’s covers all the essentials, from the basic science of skin to the day-to-day clinical issues of managing common skin disorders such as acne, skin cancer, and psoriasis. Backed by the expertise of more than 500 world-renowned contributors, and the reference of choice for clinicians, students, and educators, Fitzpatrick’s is enhanced by thousands of full-color photographs and a wealth of newly enhanced tables and diagrams. The Ninth Edition is bolstered by a new global editorial team; a reorganized table of contents; a more simple, readable, and direct writing style, the incorporation of more genetic, syndromic, and treatment information into each chapter; the addition of first, second, and third line treatment options; and improved table presentation. The reorganized table of contents reflects how disease presents rather than its cause.
Red je vel
Alles wat je moet weten om huidkanker te voorkomen Huidkanker rukt op. Elk jaar blijft het aantal nieuwe gevallen toenemen. Het goede nieuws is dat je de ziekte met de juiste levensstijl vaak kunt voorkomen. En als je toch huidkanker krijgt, kan ze in de meeste gevallen door een goede screening en een vroege behandeling goed behandeld worden. Maar daarvoor is het belangrijk om te begrijpen wat huidkanker precies is. Hoe onderscheid je een melanoom van een onschuldige moedervlek? Wat zijn de risico's van onbeschermd zonnen? Hoe schadelijk is de zonnebank voor je huid? Wanneer moet je je laten screenen? Welke behandelingen zijn er? Red je vel biedt heldere antwoorden op de meest gestelde vragen over huidkanker, gebaseerd op het recentste wetenschappelijke onderzoek.
Oncologie
Dit boek gaat in op de (veranderende) rol van de huisarts, nu en in de toekomst, bij de zorg rondom de oncologische patiënt in de dagelijkse praktijk. In een inleidend deel komen algemene onderwerpen aan bod zoals incidentie, prevalentie en sterfte-aantallen. Daarnaast gaat het in op preventie en nieuwe behandelmethoden, revalidatie, de organisatie van de oncologische zorg in Nederland en Vlaanderen en de rol van de huisarts bij palliatieve zorg. In het tweede deel worden, aan de hand van casuïstiek, de volgende vormen van kanker besproken: colorectale kanker, borstkanker, prostaatkanker, longkanker en gepigmenteerde huidkanker. Hierbij wordt vooral ingegaan op de rol van de huisarts: vana...
