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Basic scientific background Breast cancer is one of the most common cancer and the most frequent cause of cancer death among women worldwide. Currently, subtyping breast cancers into hormone receptor (HR) positive, human epidermal growth factor receptor-2 overexpressing (HER2+), and triple negative breast cancer (TNBC) is the basis of diagnosing and treating this disease. The main treatment strategies for breast cancer include surgery, endocrine therapy, molecular targeted therapy, chemotherapy, radiotherapy, immunotherapy and gene therapy. However, resistance of breast cancer cells to chemotherapeutic agents, molecular targeted therapies and immunotherapy may occur either intrinsically or d...
A tragedy is unfolding all around us and is receiving well overdue attention. Black women are three times more likely to die from pregnancy than their white peers. But Dr. Monique Rainford is working to better understand these disparities and do something about them. Pregnant While Black is a hopeful exploration of the issues pregnant Black women face in America. Within these pages, Dr. Rainford draws on over twenty years of experience working in obstetrics and gynecology to offer a primer on Black pregnancies and how to better care for them. She shares the successes and testimonies of Black women who have struggled during pregnancy and childbirth, anchoring the stories of these women with carefully researched facts. Despite medical advances over the last twenty years, for Black women, the overwhelming dangers of carrying and delivering children remain and it only seems to be getting worse. In Pregnant While Black, Rainford begins the work of "repairing the damage of the past" with an examination of the conditions that plague Black pregnancies. This important book carries the hopes and dreams of a generation looking to effect change, here and now.
The fifth volume of Dr Needham's immense undertaking, like the fourth, is subdivided into parts for ease of assimilation and presentation, each part bound and published separately. The volume as a whole covers the subjects of alchemy, early chemistry, and chemical technology (which includes military invention, especially gunpowder and rockets; paper and printing; textiles; mining and metallurgy; the salt industry; and ceramics).
This book reviews public health activities such as awareness campaigns, health education, and strategies for health policy based on recent epidemiological studies that provide insights into epigenetic processes caused by environmental factors and developmental plasticity. It provides the latest concepts and findings on the public health aspects of Developmental Origins of Health and Disease (DOHaD) research regarding early prevention of non-communicable diseases (NCDs). Attention is especially paid to key issues, including strategies for the effective prevention of NCDs in developmental stages of life and younger generations rather than in adults and the elderly. Public Health Aspects in Dev...