In Collaboration with Pathologists in 7 Countries
This book constitutes the refereed proceedings of the First International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI'98, held in Cambridge, MA, USA, in October 1998. The 134 revised papers presented were carefully selected from a total of 243 submissions. The book is divided into topical sections on surgical planning, surgical navigation and measurements, cardiac image analysis, medical robotic systems, surgical systems and simulators, segmentation, computational neuroanatomy, biomechanics, detection in medical images, data acquisition and processing, neurosurgery and neuroscience, shape analysis, feature extraction, registration, and ultrasound.
A collection of important essays on the health and well-being of African Americans in the southern United States. For African Americans in the southern United States, the social determinants of health are influenced by a unique history that encompasses hundreds of years of slavery, injustices during the Jim Crow era, the Great Migration, the civil rights era, and contemporary experiences like the Black Lives Matter movement. In Black Health in the South, editors Steven S. Coughlin, Lovoria B. Williams, and Tabia Henry Akintobi bring together essays on this important subject from top public health experts. Black activists, physicians, and communities continue to battle inequities and structur...
Gleaning information from more than 100 experts in the field of cancer diagnosis, prognosis, and therapy worldwide, Cancer Biomarkers: Non-Invasive Early Diagnosis and Prognosis determines the significance of clinical validation approaches for several markers. This book examines the use of noninvasive or minimally invasive molecular cancer m
The proceedings of this volume represent a record of a meeting in the Ettore Majorana center in Erice, Sicily from 16-24 July, 1983. This was the fifth course of the International School of Urology and Nephrology, the fourth in a series of meetings devoted to different aspects of Urological Oncology. Speakers and delegates came from nearly every part of the world and contributed to a detailed analysis of the current state of knowledge of tumors of the testicle and to the development of knowledge of cancer of the bladder, prostate and kidney. Previous volumes resulting from this series of meetings have been well received and the Editors hope that the reader may find the record of this meeting...
This book summarizes the latest findings about the role of cancer stem cells (CSCs) in cancer biology and how this knowledge could be used for novel anticancer therapies. It provides an overview of CSCs in selected malignancies with particular emphasis on hematopoietic neoplasias. It then reviews the role of CSCs in metastasis formation and initiat
Development of cancer, a dreadful disease of mankind, is a multi-stage process involving numerous molecular alterations at both genomic and proteomic levels. Immense research for the past several decades in the field of cancer identified many such mutations and their role in carcinogenesis. Concept of 'fusion genes' seeded way back in 20th century has now grown into a new field of cancer research. However, there is a lack of knowledge among scientists about these fusion genes and their importance in cancer, which can be mainly attributed to unavailability of a comprehensive book on this topic. Therefore, this book is first of its kind and aims at giving a detailed idea on the formation of gene fusions and their importance in the development and progression of cancer; techniques to identify novel gene fusions; and therapeutics available to target various fusion proteins and their impact in cancer therapy by compiling the information from the literature available till date.
Advances in Clinical Chemistry, Volume 95, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. The serial discusses the latest and most up-to-date technologies related to the field of clinical chemistry, with this new release including sections on Advances in diagnostic microfluidics, Vascular and valvular calcification biomarkers, Long noncoding RNAs in cancer: From discovery to therapeutic targets, Exosomes of male reproduction, Tryptophan in health and disease, Biochemistry of blood platelet activation, and the beneficial role of plant oils in cardiovascular diseases.
This book focuses on proteomics biomarker discovery and validation procedures from the clinical perspective. It provides an overview of current technology and the challenges encountered throughout the process. This covers all key stages, from biomarker discovery and validation, through to registration with the European and US regulatory authorities (EMEA and FDA). All the important elements (such as patient selection, sample handling, data processing, and statistical analysis) are described in detail and the reader is introduced to each topic with well described examples or guidelines for best practice. Case studies are also included to demonstrate clinical applications. Individual chapters ...
This book embraces the wide field of prostate cancer genetics, biology, and therapy. It seems most appropriate to dedicate it to Donald S. Coffey, PhD, whose research vision is an inspiration to his colleagues and friends. Unraveling the secrets of prostate cancer is an intricate and sometimes frustrating process involving many researchers and many institutions. No one has seen through to the end of this road, and the list of researchers who have contributed to our understanding of the disease processes of prostate cancer is already a long one. But Donald Coffey stands out in his personal qualities as surely as in his roles as teacher and researcher. In the dedicatory article that begins thi...