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Endocrine and Hormonal Toxicology
Endocrine and Hormonal Toxicology Edited by Philip W. Harvey, Kevin C. Rush and Andrew Cockburn AgrEvo UK Ltd, Saffron Walden, UK This is the first book to consider the integrated role of the classical endocrine system and hormones (including those from tissues outside the classical endocrine system) in toxicological responses. Although focusing on the latest knowledge on endocrine glands as target organs and the mechanistic and molecular basis for toxicity in these organs, Endocrine and Hormonal Toxicology has been written to cover toxicological responses at the whole body level mediated by endocrine or hormonal mechanisms. This whole body, multi-organ approach significantly broadens the re...
Pancreas
The pancreas is an unobtrusive organ, and the prospects and possibilities of solving the physiological and pathological nature of its behavior are numerous. When conducting a pathological study or an investigation of the pancreas, it is important to consider its anatomical and embryological basis as well as the occurrence of age-related frequent lesions. Concerning the latter, both mucous cell hyperplasia and the cystic dilatation of the branch pancreatic duct result in the modification of the tissue surrounding it, i.e. atrophy. Moreover, pathological changes in the pancreas are focal or patchy in nature, especially in non-tumorous lesions, and are related to its neighboring or adjacent organs. Based on the experience and knowledge of its contributors, this publication describes in detail various pathological changes in the behavior of the pancreas. Pathologists, physicians and surgeons who are interested in the pancreas will find it a useful reference source both for their daily work as well as for future research.
Macronutrients
Summarizes the role of macronutrients in cancer and addresses the relationship between macro- and micronutrients and other risk factors, as well as illustrates the role of intervention trials in cancer prevention research on macronutrients.
Digestive System
This is the second edition of the third volume in the Monographs on Pathology of Laboratory Animals series. Since the first edition, new information has developed at a remarkable pace. Both editions propose standardized nomenclature that is being used internationally, gaining significant acceptance. The result is improved communications of pathologic data to regulatory agencies and in scientific publications worldwide. New information on the nature and variability of preneoplastic lesions in the liver of laboratory rodents is included in this edition. The book expands data on the accompanying changes in enzyme activity in affected liver cells. Spongiosis hepatis in the rat and its relation to spongiotic pericytoma are discussed thoroughly. Information on many other pathologic entities is brought up to date and new ones are added to this second edition, making it an even more useful and expanded reference text.
Nutritional Pathology
This book examines several recent, major developments in the field of nutritional pathology, providing enhanced, current understanding of the role that altered or disturbed nutrition plays in the pathogenesis of disease. It is intended for students in pathology, nutrition, and biochemistry.
Pancreatic Cancer
A distinguished panel of world authorities reviews the current state of today's understanding, diagnosis, and treatment of pancreatic cancer. Their cutting-edge reviews discuss both medical and surgical modalities and include numerous insights into the basic molecular processes underlying the disease. Among the key topics covered are the prospects for early diagnosis using molecular techniques, the latest diagnostic and therapeutic methods, the role of laparoscopy (diagnostic and therapeutic), and nonsurgical treatment. The reviewers also address the future possibilities for clinical advances, quality of life concerns, and the value of the Japanese "extended Whipple resection." Pancreatic Cancer will become the new standard reference for all clinicians who diagnose and treat this disease, as well as for basic scientists needing a summary of the many recent advances. i
Annual Report
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Biologically Based Methods for Cancer Risk Assessment
"Biologically Based Methods for Cancer Risk Assessment", an Advanced Research Workshop, (ARW) sponsored by the North Atlantic Treaty Organization (NATO) was held in Corfu, Greece in June, 1989. The intent of the workshop was to survey available pharmacokinetic and pharmacodynamic methods in cancer risk assessment and identify methodological gaps and research needs for biologically based methods in cancer risk assessment. Incorporation of such methods represents one of the most challenging areas for risk assessment. The workshop included an international group of invited experts in the field and provided for a dynamic exchange of ideas and accomplishments. Some of the major topics discussed w...
