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Worldwide, more than half a million women are diagnosed with cervical cancer annually and more than 300,000 die from the disease. At least 85% of the deaths occur in low-middle income countries (LMICs)and almost 10% of them in Latin America (LATAM) and the Caribbean, where mortality rates are almost five times higher than in high-income areas. Infection with high-risk subtypes of the Human Papillomavirus (HPV) is a necessary, but not sufficient cause of cervical cancer. The natural history of the disease involves persistent high-risk HPV infections, followed by the development of precancerous cervical lesions, and progression to invasive cervical cancer, in a process that usually occurs thro...
This book provides readers with a thorough review on cervical cancer, treatment guidelines and emerging therapies available for the disease. It reviews the epidemiology clinical features, diagnosis, and medical management of cervical cancer. Given the increasing need for preventive strategies, treatment optimization with collaborative and integrative work, this book improves the actual and integral knowledge in this neoplasm. Given the high prevalence of this disease in Latin America, this is an important text for clinicians in this region. This book outlines the state of the art in cervical cancer treatments and is an indispensable companion for oncologists, gynecologists, surgeons and medical students.
Bernhard Varenius’ books influenced the history of science in such a way that Isaac Newton, Alexander von Humboldt and Tsar Peter the Great all referred to him. Varenius wrote the first comprehensive description of Japan (Descriptio regni Japoniae, 1649) from a European perspective, exclusively based on a diversity of sources. But the impact of his Geographia generalis (1650) explains his ranking among the founding fathers of geography as a science. He called ‘general’ geography a branch of (applied) mathematics which does not deal with regional specifics. The contributions in this book focus on his multi-faceted work, the influence of his books and the tragically short life of this young polymath from Germany who benefited from the intellectually stimulating milieu of Leiden and Amsterdam. Contributors include: Horst Walter Blanke, Reinhard Düchting, Klaus Lehmann, Robert Mayhew, Sandra Rebok, Folker Reichert, Frank Richter, Margret Schuchard, Denis J.B. Shaw, Ulrich Staffhorst, Johann Anselm Steiger, Rienk H. Vermij, and Ernst-Christian Volkmann.
The 32nd issue of the International Productivity Monitor is a special issue produced in collaboration with the OECD. All articles published in this issue were selected from papers presented at the First Annual Conference of the OECD Global Forum on Productivity held in Lisbon, Portugal, July ...
"Written by leading researchers from six countries, this is the first book to pull together the diverse range of research on self-concept from the medical sciences, psychology, sociology, physical education, and exercise and sport science. The contributors examine how the physical self motivates and determines behavior and contributes to mental health and well-being." "The Physical Self will help you trace how the concept of the physical self has evolved over the last decade and how it has contributed to our understanding of the total self."--BOOK JACKET.Title Summary field provided by Blackwell North America, Inc. All Rights Reserved
Plants produce a vast number of bioactive compounds with different chemical scaffolds, which modulate a diverse range of molecular targets and are used as drugs for treating numerous diseases. Most present-day medicines are derived either from plant compounds or their derivatives, and plant compounds continue to offer limitless reserves for the discovery of new medicines. While different classes of plant compounds, like phenolics, flavonoids, saponins and alkaloids, and their potential pharmacological applications are currently being explored, their curative mechanisms are yet to be understood in detail. This book is divided into 2 volumes and offers detailed information on plant-derived bio...
Stupidity. What is it? Is is just something we see our neighbors and parents/kids do (and members of the opposite political party)? Or is it something more? Why does it seem to be so universal? Are there fundamentals of stupidity that can be recognized? These are the questions discussed in this volume. It presents six fundamentals of stupidity that lead to the stupid choices we see all around us. Included among these are the belief that there are no moral values, that God does not exist, and that it is acceptable to become addicted and to treat others badly and be proud. In the end, we see that the only sure way to avoid the fundamentals of stupidity is through the saving power of Jesus Christ.