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We anticipate the book to be a definitive text on the subject that explores all aspects of the study of adrenal cancer and the treatment of patients with the disease. Chapters will cover epidemiology, pathogenesis, genetics, cancer stem cells, historic and emerging therapies, mouse models of adrenal cancer, new developments in tumor profiling, worldwide collaborative groups and tumor registries together with resources for the practitioner and community of adrenal cancer scientists. We do not wish this book to compete with the other larger books in the Endocrine and Endocrine Surgery literature. In addition, it is not expected to cover benign adrenal diseases that have been covered in detail in other venues. We envision this book to be a very specialized and exhaustive text on basic, translational and clinical aspects of adrenal cancer.
A cutting-edge review of how derangements in the hormonal and growth factor mechanisms controlling normal mammary development lead to breast cancer. Drawing on the multidisciplinary expertise of leading authorities, the book highlights the roles of oncogenes and tumor suppressor genes, spelling out the importance of autocrine/paracrine loops (e.g., stromal epithelial interactions) in supporting breast cancer cell proliferation and the progression to hormone independence. The book's many prominent contributors also illuminate significant recent advances in the biochemistry and physiology of hormone receptors and review the state-of -the-art in the endocrine therapy of breast cancer. Endocrinology of Breast Cancer provides a unique integrated overview of the most significant basic and clinical developments concerning the hormonal aspects of breast cancer.
Understanding Clinical Papers is a popular and well established introduction to reading clinical papers. It unravels the process of evidence-based practice, using real papers to illustrate how to understand and evaluate published research, and provides clear explanations of important research-related topics.
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Contesa da tutti, compresa da nessuno, la fantomatica «pancia del paese» è il punto ombelicale del discorso pubblico contemporaneo. Ma cosa succede se ad auscultare i borborigmi che giungono dal suo interno è uno studioso della lingua italiana? Cosa succede se, anziché evocare a sproposito un luogo divenuto ormai mitologico, si tenta di registrare e interpretare i cavernosi suoni che da quel (basso) ventre provengono? Cosa succede, insomma, se si cerca di ripercorrere il tragitto che dalla pancia conduce alla bocca e per suo mezzo alla fonazione? Inoltrandosi in questo lubrico terreno, Massimo Arcangeli fotografa un popolo di santi, poeti e ferventi imprecatori, di folli gesticolatori n...