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Dynamic Treatment Regimes
  • Language: en
  • Pages: 619

Dynamic Treatment Regimes

  • Type: Book
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  • Published: 2019-12-19
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  • Publisher: CRC Press

Dynamic Treatment Regimes: Statistical Methods for Precision Medicine provides a comprehensive introduction to statistical methodology for the evaluation and discovery of dynamic treatment regimes from data. Researchers and graduate students in statistics, data science, and related quantitative disciplines with a background in probability and statistical inference and popular statistical modeling techniques will be prepared for further study of this rapidly evolving field. A dynamic treatment regime is a set of sequential decision rules, each corresponding to a key decision point in a disease or disorder process, where each rule takes as input patient information and returns the treatment op...

Peripheral Nerve Regeneration
  • Language: en
  • Pages: 302
Modern Concepts of Peripheral Nerve Repair
  • Language: en
  • Pages: 144

Modern Concepts of Peripheral Nerve Repair

  • Type: Book
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  • Published: 2017-06-19
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  • Publisher: Springer

This book focuses on posttraumatic repair and reconstruction of peripheral nerves. Written by internationally respected specialists, it provides an overview of the challenges and the latest advances in diagnosis and treatment of traumatic peripheral nerve injuries. It presents an outline of state-of the-art procedures from diagnostics, including newest imaging techniques, over conventional and alternative surgical approaches to clinical follow-up and rehabilitation, including the latest concepts to improve functional recovery. The purely clinical topics are preceded by neuroanatomical principles and neurobiological events related to peripheral nerve transection injuries and followed by an ou...

Shape in Medical Imaging
  • Language: en
  • Pages: 319

Shape in Medical Imaging

  • Type: Book
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  • Published: 2018-11-22
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  • Publisher: Springer

This book constitutes the proceedings of the Workshop on Shape in Medical Imaging, ShapeMI 2018, held in conjunction with the 21st International Conference on Medical Image Computing, MICCAI 2018, in Granada, Spain, in September 2018. The 26 full papers and 2 short papers presented were carefully reviewed and selected for inclusion in this volume. The papers discuss novel approaches and applications in shape and geometry processing and their use in research and clinical studies and explore novel, cutting-edge theoretical methods and their usefulness for medical applications, e.g., from the fields of geometric learning or spectral shape analysis.

Emerging Functions of Septins
  • Language: en
  • Pages: 128

Emerging Functions of Septins

Together with the microfilament, microtubule and intermediate-filament networks, septins constitute an integral part of the eukaryotic cytoskeleton. Historically identified as proteins critical for septum formation in the budding yeast Saccharomyces cerevisiae, septin family GTPases are expressed and participate in the process of cytokinesis in most eukaryotes except higher plants. More than a dozen septin genes in mammals, together with various splice variants displaying tissue-specific expression patterns and flexible hetero-polymeric higher-order assembly achieve an unfathomable complexity superior to the other cytoskeletal components. Even though the initial studies in the septin field w...

Arterial Variations in Humans: Key Reference for Radiologists and Surgeons
  • Language: en
  • Pages: 419

Arterial Variations in Humans: Key Reference for Radiologists and Surgeons

  • Type: Book
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  • Published: 2017-08-16
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  • Publisher: Thieme

A one-of-a-kind reference and atlas to variations in the human arterial system Based on the landmark work Arterial Variations in Man: Classification and Frequency by Lippert and Pabst, this atlas presents the full range of arterial variations that occur in the human body. Adding an interdisciplinary perspective to the original text, Arterial Variations in Humans: Key Reference for Radiologists and Surgeons shows variations of the arteries with schematic diagrams alongside their corresponding radiological images. Chapters begin with schematic and radiological depictions of normal arterial blood supply, followed by images of the arterial variation, to enable rapid identification of individual ...

Membrane Organization and Dynamics
  • Language: en
  • Pages: 387

Membrane Organization and Dynamics

  • Type: Book
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  • Published: 2017-12-06
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  • Publisher: Springer

This volume brings together information on membrane organization and dynamics from a variety of spectroscopic, microscopic and simulation approaches, spanning a broad range of time scales. The implication of such dynamic information on membrane function in health and disease is a topic of contemporary interest. The chapters cover various aspects of membrane lipid and protein dynamics, explored using a battery of experimental and theoretical approaches. The synthesis of information and knowledge gained by utilizing multiple approaches will provide the reader with a comprehensive understanding of the underlying membrane dynamics and function, which will help to develop robust dynamic models fo...

Hereditary Tyrosinemia
  • Language: en
  • Pages: 247

Hereditary Tyrosinemia

  • Type: Book
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  • Published: 2017-07-27
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  • Publisher: Springer

Hereditary tyrosinemia type 1 (HT1), the most severe inborn error of the tyrosine degradation pathway, is due to a deficiency in fumarylacetoacetate hydrolase (FAH). The worldwide frequency of HT1 is one per 100,000 births, but some regions have a significantly higher incidence (1:1,800). The FAH defect results in the accumulation of toxic metabolites, mainly in the liver. If left untreated, HT1 is usually fatal before the age of two. HT1 patients develop several chronic complications including cirrhosis with a high risk of hepatocellular carcinoma (HCC) and neuropsychological impairment. Treatment comprises an inhibitor of the pathway, Nitisinone, a strict dietary treatment or liver transplantation. Early treatment is important to avoid HCC. The book includes the latest developments on the molecular basis of HT1, its pathology, screening and diagnosis and management of the disease written by leading scientists, geneticists, hepatologists and clinicians in the field.

La perorata
  • Language: es

La perorata

  • Type: Book
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  • Published: 2024
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  • Publisher: Unknown

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