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Abdominal and retroperitoneal sarcomas are rare tumors originating from connective tissues in the body like muscle, fat, fibrous tissue, and blood vessels. Surgery is the primary treatment option for these tumors, and complete surgical resection is the only potential cure. Typically, these tumors can be large at detection, and the management of abdominal and retroperitoneal tumors can be difficult. In addition to surgery, chemotherapy, radiation therapy, and new target therapies are the applied treatment modalities. The surgical management of abdominal and retroperitoneal sarcoma is evolving. In this special issue we want to highlight advances in the surgical management of abdominal and retroperitoneal sarcomas, including new surgical technology, minimal invasive surgery, and personalized surgery. Furthermore, we would like to address controversies in the surgical management of abdominal and retroperitoneal surgery, including, aggressive surgical approaches, compartment resection, resection of disseminated tumors, resection of recurrent disease, and the value of (neo)adjuvant chemo- and radiation therapy.
Infectious Pregnancy Complications deal with the co-occurrence of pregnancy and an infection. The infection may precede or follow fertilisation. This book presents the latest research in the field.
July 2022 is Sarcoma Cancer Awareness Month and at Frontiers in Endocrinology we want to highlight the recent discoveries in the field and raise awareness of the importance of early diagnosis of these cancers. Sarcomas is the general term for rare kinds of cancer growing in the bone and connective tissues. These tumors can be divided into two main groups, soft tissue sarcomas, and bone sarcomas. Interestingly, a new kind of sarcoma has been recently described, called pseudoendocrine sarcoma. The most common tissues affected by this kinds of sarcoma are bones, muscles, tendons, cartilage, nerves, fat, and blood vessels of your arms and legs, as well as many endocrine organs. It affects mainly...
A true story from the great age of Arctic exploration of an Inuit boy's struggle for dignity against Robert Peary and the American Museum of Natural History in turn-of-the-century New York City. Sailing aboard a ship called Hope in 1897, celebrated Arctic explorer Robert Peary entered New York Harbor with peculiar "cargo": Six Polar Inuit intended to serve as live "specimens" at the American Museum of Natural History. Four died within a year. One managed to gain passage back to Greenland. Only the sixth, a boy of six or seven with a precociously solemn smile, remained. His name was Minik. Although Harper's unflinching narrative provides a much needed corrective to history's understanding of Peary, who was known among the Polar Inuit as "the great tormenter", it is primarily a story about a boy, Minik Wallace, known to the American public as "The New York Eskimo." Orphaned when his father died of pneumonia, Minik never surrendered the hope of going "home," never stopped fighting for the dignity of his father's memory, and never gave up his belief that people would come to his aid if only he could get them to understand.
Acute Medical Emergencies is based on the popular Advanced Life Support Group course MedicALS (Medical Advanced Life Support) and is an invaluable resource for all doctors dealing with medical emergencies. This comprehensive guide deals with the medical aspects of diagnosis and treatment of acute emergencies. Its structured approach teaches the novice how to assess and recognise a patient in an acute condition, and how to interpret vital symptoms such as breathlessness and chest or abdominal pain. There are separate sections on interpretation of investigations, and procedures for managing the emergency. It covers procedures for acute emergencies occurring anywhere - on hospital wards or beyond. The clarity of the text, including simple line illustrations, ensure its tried and tested procedures provide clear, concise advice on recognition and management of medical emergencies.
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Major text including chapters on the following: defining outcome measures; assessing heterogeneity; using fixed effects methods and random effects models for combining study estimates; publication bias.
This book provides a comprehensive introduction to performing meta-analysis using the statistical software R. It is intended for quantitative researchers and students in the medical and social sciences who wish to learn how to perform meta-analysis with R. As such, the book introduces the key concepts and models used in meta-analysis. It also includes chapters on the following advanced topics: publication bias and small study effects; missing data; multivariate meta-analysis, network meta-analysis; and meta-analysis of diagnostic studies.