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In genetic pathology, epigenetic testing is rare and under utilised. In this book, we introduce epigenetics to a non-expert scientific audience and describe current and future clinical utility of epigenetic testing. By focussing on epigenetics in human disease this book will guide professionals (scientists and clinicians) to understand how epigenetics is relevant in a clinical context, and to implement epigenetic testing in diagnostic laboratories. The book begins with a historical perspective of genetics and epigenetics and describes the work of pioneers who have helped shape these fields. The various mechanisms by which epigenetics can regulate the function of the genome is described. Thes...
This volume of Energy Balance and Cancer provides state-of-the-art descriptions of the rapidly evolving science of epigenetics and how it may explain mechanisms by which alterations in energy balance such as obesity and physical activity may impact cancer. In addition to chapters explaining the processes mediating epigenetic regulation, the volume contains a series of chapters explaining how environmental influences including early life events, nutrition, exercise and microbiota may induce epigenetic changes that can affect carcinogenesis. The following chapters describe epigenetic relations of energy balance to cancer in distinct organ systems including esophagus, colon, prostate and breast. Epigenetics, Energy Balance and Cancer provides a valuable resource for students, research investigators and clinicians seeking to better understand these processes as well as a basis for novel translational and transdisciplinary approaches to further elucidate these processes and develop preventive and therapeutic strategies.
DNA methylation is an epigenetic process that occurs when a methyl group binds to one of DNA's four bases, cytosine. These changes are responsible for controlling the activity of genes by turning them off. This book contains ten articles that explore the details and challenges of cancer epigenetics.
A military and social history of the Sixty-sixth Ohio Volunteer Infantry and the wartime Champaign County, Ohio. It deals with the homefront, morale, reenlistment, and the memory and commemoration of the war. It includes the words and stories of individual soldiers.
W.E Vine's greatest contribution to the Church of God was his Expository Dictionary of New Testament Words. W. E. Vine has put all English-speaking Bible students in his debt. The English reader with little or no knowledge of Greek has, of course, concordances and lexicons. These provide a skeleton: Vine clothes it with the flesh and sinews of living exposition, and in so doing makes available for the ordinary reader the expert knowledge contained in the more advanced works. In a preface to the dictionary, W. E. Vine wrote: "In any work in which we engage as servants of Christ, His word ever applies, 'When ye shall have done all those things that are commanded you, say, We are unprofitable servants; we have done that which was our duty to do.
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