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A large number of diseases affect salivary gland (SG) secretion through different mechanisms, leading to SG dysfunction and associated oral problems. The glands may suffer from viral, bacterial, and, albeit rarely, fungal infections, which may cause painful swelling or obstruction; they could also become the target of an autoimmune attack or may be affected by various benign and malignant tumors which consist of a heterogeneous group of lesions with complex clinical–pathological characteristics. The loss of normal SG function results in widespread deterioration of oral health. This book, entitled “Diseases of Salivary Glands”, provides an overview of recent advances in the field of SG disorders, focusing on the cellular and molecular mechanisms involved in the pathogenesis of SG diseases and on the most innovative investigation techniques that could help to preserve patients’ health, function, and quality of life.
Bridging the gap between basic scientific advances and the understanding of liver disease — the extensively revised new edition of the premier text in the field. The latest edition of The Liver: Biology and Pathobiology remains a definitive volume in the field of hepatology, relating advances in biomedical sciences and engineering to understanding of liver structure, function, and disease pathology and treatment. Contributions from leading researchers examine the cell biology of the liver, the pathobiology of liver disease, the liver’s growth, regeneration, metabolic functions, and more. Now in its sixth edition, this classic text has been exhaustively revised to reflect new discoveries ...
This book is open access under a CC BY 4.0 license. This handbook synthesizes and analyzes the growing knowledge base on life course health development (LCHD) from the prenatal period through emerging adulthood, with implications for clinical practice and public health. It presents LCHD as an innovative field with a sound theoretical framework for understanding wellness and disease from a lifespan perspective, replacing previous medical, biopsychosocial, and early genomic models of health. Interdisciplinary chapters discuss major health concerns (diabetes, obesity), important less-studied conditions (hearing, kidney health), and large-scale issues (nutrition, adversity) from a lifespan vi...
As a spectroscopic method, Nuclear Magnetic Resonance (NMR) has seen spectacular growth over the past two decades, both as a technique and in its applications. Today the applications of NMR span a wide range of scientific disciplines, from physics to biology to medicine. Each volume of Nuclear Magnetic Resonance comprises a combination of annual and biennial reports which together provide comprehensive of the literature on this topic. This Specialist Periodical Report reflects the growing volume of published work involving NMR techniques and applications, in particular NMR of natural macromolecules which is covered in two reports: "NMR of Proteins and Acids" and "NMR of Carbohydrates, Lipids...
"Eating Immortally" reveals the revolutionary link between nutrition and a vital, energized life. Renowned nutrition expert Professor Boris Bigalke, MD, MBA (Oxford, UK), LL.M. presents groundbreaking findings that turn conventional notions of health and vitality on their head. Based on years of research and clinical experience, this book offers a comprehensive guide for anyone who wants to live life at full throttle. With a unique mix of science-based information and practical tips, Professor Bigalke shows how a targeted diet and exercise program can help slow the aging process, regenerate cells and boost energy to explosive levels. From superfoods to 50 selected recipes for different stage...
Alterations in the normal DNA methylation processes are known to have major consequences for embryonic development and are associated with congenital defects, autoimmunity, aging and malignant transformation. The main purpose of this book is to provide information about the importance of methylation mechanisms in human health and disease. The book, covers the basic mechanism of DNA and protein methylation, aiming at the advanced undergraduate and graduate biomedical students and researchers working in the epigenetic area. The textbook chapters provide background as well as advanced information in the methylation area. On the other hand, it provide readers with both classical and relevant recent discoveries that have been made in the field, pointing out pathways where questions remain.
"Eating Immortally" reveals the revolutionary link between nutrition and a vital, energized life. Renowned nutrition expert Professor Boris Bigalke, MD, MBA (Oxford, UK), LL.M. presents groundbreaking findings that turn conventional notions of health and vitality on their head. Based on years of research and clinical experience, this book offers a comprehensive guide for anyone who wants to live life at full throttle. With a unique mix of science-based information and practical tips, Professor Bigalke shows how a targeted diet and exercise program can help slow the aging process, regenerate cells and boost energy to explosive levels. From superfoods to 50 selected recipes for different stage...
The Charnolosome as a Novel Nanothereranostic Biomarker: Overcoming Future Challenges in Medicine provides an overview of the charnolosome and its potential as a biomarker of cell injury. Based on the author's original discovery of the charnoly body in the developing, undernourished rat cerebellar Purkinje neurons, this book delves into the potential for utilizing this mitochondria and lysosomal-derived intracellular organelle as a nanotheranostic biomarker to prevent and cure various diseases. The book discusses the cellular, molecular, genetic, and epigenetic mechanisms of charnolosomes and charnolosome-derived nano-vesicles. It also investigates the molecular mechanisms underlying auto-in...
This book comprehensively describes essential research and projects on climate change and biodiversity. Moreover, it includes contributions on how to promote the climate agenda and biodiversity conservation at the local level. Climate change as a whole and global warming in particular are known to have a negative impact on biodiversity in three main ways. Firstly, increases in temperatures are detrimental to a number of organisms, especially those in sensitive habitats such as coral reefs and rainforests. Secondly, the pressures posed by a changing climate may lead to sets of responses in areas as varied as phenology, range and physiology of living organisms, often leading to changes in thei...
This book is an edited collection of the literature on leptin beginning with the discovery of leptin and a study of its affect on animals and in humans. Chapters will focus on the discovery, history, roles and regulation of leptin in all the major areas of physiology, as well as on assay methods, phylogeny and genetics. The timing of this volume is long overdue and is the first comprehensive coverage of leptin physiology in the field.