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Multiple Sclerosis Therapeutics
This book comprehensively reviews the current state of clinical trial methods in multiple sclerosis treatment, providing investigators, sponsors and specialists with current knowledge of outcome measures and study designs for disease and symptom management. The status of the rapidly evolving field of disease-modifying drugs is presented, with emphasis on the most promising therapies currently being tested. Experts discuss disease and symptom management for MS subtypes, including neuromyelitis optica and pediatric MS. In addition, key scientific advances in MS pathology, genetics, immunology and epidemiology are presented. The fourth edition has been extensively revised, featuring more than 50% new material. All chapters have been substantially updated to provide current information on rapidly evolving topics and this volume contains 15 new chapters, reflecting the growth of the field in recent years. This book is an essential reference for practitioners caring for MS patients, investigators planning or conducting clinical trials, and clinical trial sponsors.
Foundations of Augmented Cognition: Neuroergonomics and Operational Neuroscience
This volume constitutes the refereed proceedings of the 10th International Conference on Foundations of Augmented Cognition, AC 2016, held as part of the 18th International Conference on Human-Computer Interaction, HCII 2016, which took place in Toronto, Canada, in July 2016. HCII 2016 received a total of 4354 submissions, of which 1287 papers were accepted for publication after a careful reviewing process. The 50 papers presented in this volume were organized in topical sections named: brain-computer interfaces; electroencephalography and brain activity measurement; and cognitive modeling and physiological measuring.
Bioreactor Systems for Tissue Engineering II
Alternative Sources of Adult Stem Cells: Human Amniotic Membrane, by S. Wolbank, M. van Griensven, R. Grillari-Voglauer, and A. Peterbauer-Scherb; * Mesenchymal Stromal Cells Derived from Human Umbilical Cord Tissues: Primitive Cells with Potential for Clinical and Tissue Engineering Applications, by P. Moretti, T. Hatlapatka, D. Marten, A. Lavrentieva, I. Majore, R. Hass and C. Kasper; * Isolation, Characterization, Differentiation, and Application of Adipose-Derived Stem Cells, by J. W. Kuhbier, B. Weyand, C. Radtke, P. M. Vogt, C. Kasper and K. Reimers; * Induced Pluripotent Stem Cells: Characteristics and Perspectives, by T. Cantz and U. Martin; * Induced Pluripotent Stem Cell Technology...
Neuropsychological Assessment of Neuropsychiatric and Neuromedical Disorders
This is a major revision of a standard reference work for neuropsychologists, psychiatrists, and neurologists. About one-half of the book contains entirely new work by new contributors. New topics not covered in the previous editions include consideration of common sources of neurocognitive morbidity, such as multiple sclerosis, diabetes, and exposure to heavy metals; psychiatric and behavioral disorders associated wtih traumatic brain injury; neuropsychology in relation to everyday functioning; the effects of cognitive impairment on driving skills, and adherence to medical treatments. The Third Edition aims to reflect the enormous developments in neuropsychology in terms of research, clinic...
Chronic Obstructive Lung Diseases
In the tradition of Schwarz and King, this work brings together internationally renowned contributors from the front lines of pulmonary medicine and research in one timely and authoritative compendium. It takes a new and comprehensive look at a large medical problem - chronic obstructive lung diseases are a problem of global importance and the incidence of COPD is increasing in many countries and COPD is an important cause of morbidity and mortality. The focus is on the pathobiology of COPD and emphysema, on the exacerbation of COPD and on treatment options.
Natural Biomaterials for Tissue Engineering
Natural Biomaterials for Tissue Engineering is a comprehensive reference that provides in-depth principles for supporting and enabling knowledge during the tissue production process, focusing on different cell systems. The tissue fabrication process is illustrated with specific examples for more than 30 tissues, which may soon lead to new tissue engineering therapies. The section coverage includes an overall introduction, decellularization protocols specific to each tissue, characterization, materials and methods, cell seeding process, preclinical evaluation in laboratory animals, clinical applications, limitations, conclusion, and future challenges. Readers may turn to this up-to-date coverage for a widespread understanding of regenerative medicine, which will be useful to students and experts alike. - Covers the basics of regenerative medicine to more advanced topics for clinical applications of tissue-engineered scaffolds - Includes chapters that explore in-depth principles for tissue production process - Provides over 30 tissue examples
Cognitive Neurology
The study of patients affected by disorders of the central nervous system is one of the crucial research methods for investigating the organization of cognitive functions in the brain. However, many clinicians remain unaware of the significant advances that have taken place in the field of cognitive neuroscience in the last decades. This book provides an introduction to the cognitive and behavioural aspects of the clinical practice of neurology. Most of the contributors to this book combine an active clinical practice with a leading role in their respective research area, and have provided concise summaries of the theoretical advances which they consider as potentially relevant for the clini...
Neurobiology of Mental Illness
This is a new edition of the first comprehensive text to show how the advances in molecular and cellular biology and in the basic neurosciences have brought the revolution in molecular medicine to the field of psychiatry. The book begins with a review of basic neuroscience and methods for studying neurobiology in human patients then proceeds to discussions of all major psychiatric syndromes with respect to knowledge of their etiology, pathophysiology, and treatment. Emphasis is placed on synthesizing information across numerous levels of analysis, including molecular biology and genetics, cellular physiology, neuroanatomy, neuropharmacology, and behavior, and in translating information from ...
Emergence of In Vitro 3D Systems to Model Human Malaria
This book illustrates the importance and advances of the disease model for malaria, a globally affected public health problem. This book provides comprehensive information on the malaria biology in a liver and all in vitro platforms for liver-stage malaria, including principles, protocols, applications for disease modeling and drug screening, and their limitations. The initial chapter describes the basis of stem cells in liver generation during development and in adults. The subsequent chapters highlight recent and emerging advances in liver organoid and liver-on-a-chip in modeling malaria. The book presents current protocols and methods to generate liver organoid and liver-on-a-chip togethe...
