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25 Years of p53 Research
p53 has emerged as a key tumor suppressor and important target for novel cancer therapy. This book, written by world-leading p53 researchers including many of those who have shaped the field over the past 25 years, provides unique insights into the progress of the field and the prospects for better cancer diagnosis and therapy in the future.
European Directors and Their Films
In European Directors and Their Films: Essays on Cinema, Bert Cardullo offers readable analyses of some of the most important film artists and individual films of the last several decades. Beyond simple biographical capsules and plot summaries, these readings demonstrate with elegance and clarity what cinema means as well as shows, explaining how international moviemakers use the resources of the medium to pursue complex, significant human goals.
p53
Our understanding of human cancer in the past 40 years has been driven by linking innovative concepts and cutting edge technologies to key problems identified by clinical research. Some of the successes in cancer genetics identified from clinical work have been the identification of specific gene deletions in human chromosomes, the use of PCR-based cloning methodologies to identify and clone human cancer genes, the validation of the human cancer genes using transgenetic technologies in the mouse, and the ability to sequence whole genomes that has recently allowed a collation of all somatic and germline mutations in a human genome. In the same generation, entirely different disciplines involv...
Epigenetics and Cancer, Part B
Genes interact with the environment, experience, and biology of the brain to shape an animal's behavior. This latest volume in Advances in Genetics, organized according to the most widely used model organisms, describes the latest genetic discoveries in relation to neural circuit development and activity. - Explores the latest topics in neural circuits and behavior research in zebrafish, drosophila, C.elegans, and mouse models - Includes methods for testing with ethical, legal, and social implications - Critically analyzes future prospects
Bioinformatics Research and Development
This book constitutes the refereed proceedings of the First International Bioinformatics Research and Development Conference, BIRD 2007, held in Berlin, Germany in March 2007. The 36 revised full papers are organized in topical sections on microarray and systems biology and networks, medical, SNPs, genomics, systems biology, sequence analysis and coding, proteomics and structure, databases, Web and text analysis.
Screen Writings
'Screen Writings: Partial Views of a Total Art, Classic to Contemporary' offers close readings of individual films intended to explain how moviemakers use the resources of the medium to pursue complex and significant humanistic goals. It fills the middle ground between vague, simple plot summaries and theoretical pronouncements. As such, this book can be considered a call for the return of practical criticism as the best way to understand and appreciate the work of cinematic artists.
The Dardenne Brothers’ Cinematic Parables
The Dardenne Brothers’ Cinematic Parables examines the work of Belgian filmmakers Jean-Pierre and Luc Dardenne, who have been celebrated for their powerfully affecting social realist films. Though the Dardenne brothers’ films rarely mention religion or God, they have received wide recognition for their moral complexity and spiritual resonance. This book brings the Dardennes’ filmography into consideration with theological aesthetics, Christian ethics, phenomenological film theory, and continental philosophy. The author explores the brothers’ nine major films—beginning with The Promise (1996) and culminating in Young Ahmed (2019)—through the hermeneutics of philosopher Paul Ricoeu...
Epigenetics and Cancer, Part A
Genes interact with the environment, experience, and biology of the brain to shape an animal's behavior. This latest volume in Advances in Genetics, organized according to the most widely used model organisms, describes the latest genetic discoveries in relation to neural circuit development and activity. - Explores the latest topics in neural circuits and behavior research in zebrafish, drosophila, C.elegans, and mouse models - Includes methods for testing with ethical, legal, and social implications - Critically analyzes future prospects
Encyclopedia of Cancer
This comprehensive encyclopedic reference provides rapid access to focused information on topics of cancer research for clinicians, research scientists and advanced students. Given the overwhelming success of the first edition, which appeared in 2001, and fast development in the different fields of cancer research, it has been decided to publish a second fully revised and expanded edition. With an A-Z format of over 7,000 entries, more than 1,000 contributing authors provide a complete reference to cancer. The merging of different basic and clinical scientific disciplines towards the common goal of fighting cancer makes such a comprehensive reference source all the more timely.
