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Advances in Clinical Trial Biostatistics
From aspects of early trials to complex modeling problems, Advances in Clinical Trial Biostatistics summarizes current methodologies used in the design and analysis of clinical trials. Its chapters, contributed by internationally renowned methodologists experienced in clinical trials, address topics that include Bayesian methods for phase I clinical trials, adaptive two-stage clinical trials, and the design and analysis of cluster randomization trials, trials with multiple endpoints, and therapeutic equivalence trials. Other discussions explore Bayesian reporting, methods incorporating compliance in treatment evaluation, and statistical issues emerging from clinical trials in HIV infection.
A Practical Guide to Designing Phase II Trials in Oncology
How to identify optimal phase II trial designs Providing a practical guide containing the information needed to make crucial decisions regarding phase II trial designs, A Practical Guide to Designing Phase II Trials in Oncology sets forth specific points for consideration between the statistician and clinician when designing a phase II trial, including issues such as how the treatment works, choice of outcome measure and randomization, and considering both academic and industry perspectives. A comprehensive and systematic library of available phase II trial designs is included, saving time otherwise spent considering multiple manuscripts, and real-life practical examples of using this approa...
Spatial Aspects of Settlement Patterns
The thirty-five papers in this festschrift, in honour of Dr. Ravindra N. Sharma, Dean of the Library at Monmouth University, West Long Branch, New Jersey, USA, attempt to analyse the different aspects of South Asian Librarianship. Highlighting the wide-ranging contributions of Dr. Sharma towards the development of library and information science, the contributors address issues concerning library and information science education. They also deliberate on the problems and prospects of University libraries, National and Public libraries and special libraries; information systems and networks; bibliographical control; and technical services.
Villages in the Future
Life in rural communities is bound to change with historically unprecedented speed in the coming decades. How will this change be guided by local, national and global policies in order to enhance the livelihoods of rural inhabitants and to overcome the growing division of rural and urban areas? The contributions in this publication, ranging from scientific papers to short reports from practitioners, are grouped around 4 major themes: political and institutional frameworks to foster rural development; natural resources management; broadening the technological base of rural economies; and improved linkages between urban and rural areas. The overall message is unanimous: there is a promising future for the rural areas worldwide if adequate policies can be enforced and more efficient and fair institutions can be created.
Multivariable Model - Building
Multivariable regression models are of fundamental importance in all areas of science in which empirical data must be analyzed. This book proposes a systematic approach to building such models based on standard principles of statistical modeling. The main emphasis is on the fractional polynomial method for modeling the influence of continuous variables in a multivariable context, a topic for which there is no standard approach. Existing options range from very simple step functions to highly complex adaptive methods such as multivariate splines with many knots and penalisation. This new approach, developed in part by the authors over the last decade, is a compromise which promotes interpretable, comprehensible and transportable models.
Handbook of Research on Recent Developments in Intelligent Communication Application
The communication field is evolving rapidly in order to keep up with society’s demands. As such, it becomes imperative to research and report recent advancements in computational intelligence as it applies to communication networks. The Handbook of Research on Recent Developments in Intelligent Communication Application is a pivotal reference source for the latest developments on emerging data communication applications. Featuring extensive coverage across a range of relevant perspectives and topics, such as satellite communication, cognitive radio networks, and wireless sensor networks, this book is ideally designed for engineers, professionals, practitioners, upper-level students, and academics seeking current information on emerging communication networking trends.
Bayesian Approaches to Clinical Trials and Health-Care Evaluation
READ ALL ABOUT IT! David Spiegelhalter has recently joined the ranks of Isaac Newton, Charles Darwin and Stephen Hawking by becoming a fellow of the Royal Society. Originating from the Medical Research Council’s biostatistics unit, David has played a leading role in the Bristol heart surgery and Harold Shipman inquiries. Order a copy of this author’s comprehensive text TODAY! The Bayesian approach involves synthesising data and judgement in order to reach conclusions about unknown quantities and make predictions. Bayesian methods have become increasingly popular in recent years, notably in medical research, and although there are a number of books on Bayesian analysis, few cover clinical...
Clinical Trials in Neurology
Clinical Trials in Neurology comprehensively tackles the methodology and design of clinical trials in neurological disease. A general section deals with the ethical aspects, drug development and regulatory requirements, basic trial designs and the statistics used. A diseases section tackles specific aspects of disorders, focusing on the relevant ethical issues, outcome variables and experience with large multicentre trials.
A Step Towards Society 5.0
This book serves the need for developing an insight and understanding of the cutting-edge innovation in Cloud technology. It provides an understanding of cutting-edge innovations, paradigms, and security by using real-life applications, case studies, and examples. This book provides a holistic view of cloud technology theories, practices, and future applications with real-life examples. It comprehensively explains cloud technology, design principles, development trends, maintaining state-of-the-art cloud computing and software services. It describes how cloud technology can transform the operating contexts of business enterprises. It exemplifies the potential of cloud computing for next-generation computational excellence and the role it plays as a key driver for the 4th industrial revolution in Industrial Engineering and a key driver for manufacturing industries. Researchers, academicians, postgraduates, and industry specialists will find this book of interest.
