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Umbilical Cord Blood Banking for Clinical Application and Regenerative Medicine
Umbilical cord blood (UCB) and, more recently, umbilical cord tissue (UCT) have been stored cryopreserved in private and public cord blood and tissue banks worldwide, since the umbilical cord blood was used for the first time in a child with Fanconi anemia with his HLA-identical sibling, following strict guidelines that imply high-quality standards and total rastreability of these units. The hematopoietic stem cells (HSCs) are clinically used in hematopoietic treatments for blood disorders and hemato-oncological diseases. Also, the mesenchymal stem cells (MSCs) isolated from the UCT and UCB, nowadays, can be used as coadjuvants of hematopoietic transplants. In the near future, these stem cel...
Thalassemia
Thalassemia is one of the most common genetic disorders worldwide and presents major public health and social challenges in areas of high incidence. The frequency of this disorder varies considerably with geographic locations and racial groups. Thalassemia refers to a group of inherited hemolytic anemia disorders that involve defects in the synthesis of hemoglobin α- or β-polypeptide chains. It leads to decreased hemoglobin production and hypochromic microcytic anemia associated with erythrocyte dysplasia and destruction. Homozygous β-thalassemia (also known as thalassemia major, Cooley's anemia, or Mediterranean anemia) is associated with the most severe signs and symptoms. Thalassemia m...
The Alcoholic Family in Recovery
Family relationships change dramatically when one or more members stops drinking. Far from offering a "quick fix" to family problems, in fact, the first years of sobriety are often marked by continuing tension that fuels marital stress, acting-out kids, and difficulties at work. This book explores the process of recovery from addiction as it affects the entire family, presenting an innovative model for understanding and treating families navigating this difficult period. The authors draw upon extensive clinical and research experience to demonstrate how families can be helped to regroup after abstinence, weather periods of emotional upheaval, and find their way to establishing a more stable, yet flexible, family system.
Alice Greene, Teacher and Campaigner
Alice Greene (1858-1920) overcame parental opposition to higher education, qualified as a teacher and in 1887 accepted a post at the Collegiate School for Girls in Port Elizabeth, South Africa. Another teacher was Elizabeth Molteno, the eldest of 18 children of Sir John Charles Molteno, the first prime minister of Cape Colony. death in 1920, and their letters as this relationship developed make fascinating reading. Alice's letters described events at school, frequently with a humorous note, her travels to up-country farms and towns during school holidays, while letters from the family kept her abreast of their activities in England and elsewhere. After the Jameson Raid at the end of 1895, sh...
Advances in Immunology
Advances in Immunology
In a Land of Paper Gods
Shortlisted for the Royal Society of Literature Ondaatje Prize 2017. A brilliantly distinctive debut set in China in the Second World War, IN A LAND OF PAPER GODS by Rebecca Mackenzie will appeal to readers who loved Oranges Are Not The Only Fruit or The Light Between Oceans. Jiangxi Province, China, 1941. Atop the fabled mountain of Lushan perches a boarding school for the children of British missionaries. While her parents pursue their calling, ten-year-old Henrietta S. Robertson discovers that she, too, has been singled out by the Lord. As Japanese invaders draw closer, Etta and her dorm mates retreat into a world where boundaries between make believe and reality become dangerously blurred. So begins a remarkable journey, through a mystical landscape and to the heart of a war.
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