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Immunochemistry
This work offers comprehensive coverage of the chemical and physicochemical aspects of immunological interactions, as well as the molecules and moieties involved in these interactions. It covers in detail the Ag-Ab interaction, including attraction at a distance between epitope and paratope. College or university bookstores may order five or more copies at a special student price, available upon request.
Recombinant Antibodies
The first part of this book combines basic information on antigens and antibodies with a review of technologies for both the development of recombinant antibodies and their application. The principles involved in producing recombinant antibodies from either pre-existing monoclonal antibodies or from phage display libraries are introduced with practical examples. Modern methods for the analysis of antibody binding properties are described in detail. Examples are given in the second part of this book for the application of recombinant antibody technology to antibody-mediated resistance to plant disease and immunomodulation of plant antigens. The potential of antibody-expressing plants as bioreactors for large-scale production and storage of recombinant antibodies is described and a future outlook given.
Microbial Imaging
Recent advances in molecular technology have provided new microbial imaging tools, not only complementing more classical methods, but in many cases significantly enhancing the sensitivity and efficiency in which studies may be conducted. These technologies are applicable to a wide range of problems in contemporary microbiology, including strain selection, understanding microbial structure, function and pathophysiology, as well as in the development of anti-microbial agents and vaccines. This volume emphasizes detailed methodology, provides a theoretical background and lists potential applications of specific imaging tools. * Edited by two experts in the field * Applicable to a broad Microbiology readership * Highly illustrated * Provides in-depth accounts from scientists working with cutting edge technologies * Facilitates researchers who involve Microbial Imaging in their work
Viral Pandemics
This new edition of Viral Pandemics illuminates how the increasing emergence of novel viruses has combined with intensifying global interconnectedness to create an escalating spiral of viral disease. It includes an introduction to the key characteristics of viral pathogens that make them so dangerous followed by a comprehensive survey of epidemic viral disease from 1900 to the present. Now featuring new chapters on COVID-19 and mpox, the book uses an historical narrative to follow the path of each virus from its original detection to its emergence as an explosive pandemic. This allows readers to appreciate the biologic potential of the virus, the dynamics of epidemic disease spread, and the ...
Bacteriophages
This volume, the first of a two-part series, covers topics including historical, ecological and evolutionary considerations, genomics and molecular biology, and interaction of phages with their hosts.
Influenza Virus Vaccines and Immunotherapies
Influenza virus infections lead to thousands of deaths worldwide annually and billions of dollars economic burden. Despite continuing advances in our understanding of the immune evasion mechanism, the disease remains one of the foremost threat for human being. Traditional vaccines (attenuated and inactivated) mainly provide protection by inducing virus neutralizing antibodies, targeting ever changing surface antigens: Haemagultinin (HA) and Neuraminidase (NA). Due to genetic shift and immune selection pressure, prevalence of circulating influenza virus subtypes changes every year. Therefore, mismatch between circulating strain and vaccine strain can critically affect the success rate of thes...
Nobel Prizes And Life Sciences
The Nobel Prizes in natural sciences have developed to become a unique measure of scientific excellence. Using archival documents, which have been released (50 years secrecy) for scholarly work, the author expertly traces the strengths and weaknesses of the Nobel system as exemplified by individual prizes. Surveys of the more than 100 years that the Prizes have been awarded are also presented.This book discusses the most important prize in the world of science and gives unique historical insights into how the laureate selection process has developed to secure optimal choice.No other book has been published which draws from previously classified archival materials to the extent that this book does. It indirectly deals with factors that foster scientific discoveries viz. the role of both individuals and institutions and thus provides invaluable insights for researchers, institutions and anyone interested in science.
Progress in Drug Research / Fortschritte der Arzneimittelforschung / Progrès des recherches pharmaceutiques
Volume 43 of «Progress in Drug Research» contains five reviews and the various indexes which facilitate its use and establish the connection with the previous volumes. The articles in this volume deal with high cholesterol blood levels and other dyslipidemias; search of ideal antihypertensive drugs; the natural PQlyamines and the immune system; biologically active quinazolones and with production and action of interferons. In the 35 years the PDR has existed, the Editor has enjoyed the valuable help and advice of many colleagues. Readers, the authors of the reviews, and last but not least, the reviewers have all contributed greatly to the success of this series. Although the comments recei...
The Present Situation in the Philosophy of Science
This volume is a serious attempt to open up the subject of European philosophy of science to real thought, and provide the structural basis for the interdisciplinary development of its specialist fields, but also to provoke reflection on the idea of ‘European philosophy of science’. This efforts should foster a contemporaneous reflection on what might be meant by philosophy of science in Europe and European philosophy of science, and how in fact awareness of it could assist philosophers interpret and motivate their research through a stronger collective identity.The overarching aim is to set the background for a collaborative project organising, systematising, and ultimately forging an identity for, European philosophy of science by creating research structures and developing research networks across Europe to promote its development.
Viruses and Virus Diseases of Poaceae (Gramineae)
Many well-known specialists have contributed to this book which presents for the first time an in-depth look at the viruses, their satellites and the retrotransposons infecting (or occuring in) one plant family: the Poaceae (Gramineae). After molecular and biological descriptions of the viruses to species level, virus diseases are presented by crop: barley, maize, rice, rye, sorghum, sugarcane, triticales, wheats, forage, ornamental and lawn. A detailed index of the viruses and taxonomic lists will help readers in the search for information.
