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Cell Biology
This four-volume laboratory manual contains comprehensive state-of-the-art protocols essential for research in the life sciences. Techniques are presented in a friendly step-by-step fashion, providing useful tips and potential pitfalls. The important steps and results are beautifully illustrated for further ease of use. This collection enables researchers at all stages of their careers to embark on basic biological problems using a variety of technologies and model systems. This thoroughly updated third edition contains 165 new articles in classical as well as rapidly emerging technologies. Topics covered include: Cell and Tissue Culture: Associated Techniques, Viruses, Antibodies, Immunocyt...
The Yeast Two-hybrid System
Biologists have already identified thousands of new gene sequences, and genome sequencing efforts are speeding up the discovery process even further. With this explosion of sequence information comes the need to understand how genes work in concert in order to fulfill the cells functions. The yeast two-hybrid system--used to identify protein-protein interactions--is one of the most powerful and versatile methods for characterizing a protein's function. It has become an essential tool for both academic researchers and those in biotechnology and pharmaceutical companies. This volume presents work by pioneers in the field and is the first publication devoted solely to the yeast two-hybrid syste...
Computational Biology
This book presents a selection of revised full papers accepted for presentation at the First International Conference on Biology, Informatics, and Mathematics, JOBIM 2000, held in Montpellier, France, in May 2000. The 13 papers included in the book were selected after two rounds of reviewing and revision from a total of 67 submissions. Among the topics addressed are algorithms, comparative genomics, evolution, phylogeny, databases, knowledge processing, genome anotation, graph theory, combinatorial mathematics, macromolecular structures, RNA and proteins, metabolic pathways and regulatory networks, and statistics and classification.
Complete Works of Jules Verne (illustrated): A Jorney To The Centre Of The Earth, From The Earth To The Moon, The Floating Island, The Children Of Capitan Grant, Twenty Thousand Leagues Under The Sea
Jules Verne, a 19th-century French author, is famed for such revolutionary science-fiction novels as “Around the World in Eighty Days” and “Twenty Thousand Leagues Under the Sea”. He has sometimes been called the "Father of Science Fiction", a title that has also been given to H. G. Wells and Hugo Gernsback. In all, Verne authored more than 60 books (most notably the 54 novels comprising the “Voyages Extraordinaires”), as well as dozens of plays, short stories and librettos. He conjured hundreds of memorable characters and imagined countless innovations years before their time, including the submarine, space travel, terrestrial flight and deep-sea exploration. Verne is generally ...
How to Influence and Persuade
Everyone operating in business needs to understand how they should be using both influence and persuasion to make an impact, deliver outstanding results and really get ahead. This brand new edition of How to Influence, is structured into three easy-to-access sections that will show you how to create willing allies across your organisation, turn potential crises into career defining opportunities, turn disagreement into consent, win key battles without fighting, push your agenda forward with authority, achieve more and stay in control. Author Jo Owen is highly regarded as a world-leading expert in business practise and skills.
Protein Arrays, Biochips and Proteomics
From disease marker identification to accelerated drug development, Protein Arrays, Biochips, and Proteomics offers a detailed overview of current and emerging trends in the field of array-based proteomics. This reference focuses on innovations in protein microarrays and biochips, mass spectrometry, high-throughput protein expression, protein-prote
Oncogenes as Transcriptional Regulators
The intensive study of molecular events leading to cellular transformation in tissue culture or in intact organisms culminated in the identification of 100 or more genes that can be defined as oncogenes or tumor suppressor genes. Functionally, these genes can be divided into several classes, each involved in a different step in transmission of signals from the exterior of the cell to the nucleus. The first oncogenes to be biochemically character ized included membrane receptors for growth factors, growth factors themselves, protein kinases or small GTP binding proteins involved in signal transduction. Later, the development of techniques to study pro teins-DNA interaction in eucaryotes and t...
Homo Conexus
Homo Conexus is the type of people we become as we venture forward into the network society. From the networks in our brains to the networks on our computers, networks are changing the way we think about ourselves and the world. Homo Conexus helps you make sense of this new age of information and networks.
Network Medicine
Big data, genomics, and quantitative approaches to network-based analysis are combining to advance the frontiers of medicine as never before. Network Medicine introduces this rapidly evolving field of medical research, which promises to revolutionize the diagnosis and treatment of human diseases. With contributions from leading experts that highlight the necessity of a team-based approach in network medicine, this definitive volume provides readers with a state-of-the-art synthesis of the progress being made and the challenges that remain. Medical researchers have long sought to identify single molecular defects that cause diseases, with the goal of developing silver-bullet therapies to trea...
