You may have to Search all our reviewed books and magazines, click the sign up button below to create a free account.
With no biological boundaries between neurodegenerative diseases as defined today, Brain Fables offers a blueprint for precision medicine.
Precision Medicine for Investigators, Practitioners and Providers addresses the needs of investigators by covering the topic as an umbrella concept, from new drug trials to wearable diagnostic devices, and from pediatrics to psychiatry in a manner that is up-to-date and authoritative. Sections include broad coverage of concerning disease groups and ancillary information about techniques, resources and consequences. Moreover, each chapter follows a structured blueprint, so that multiple, essential items are not overlooked. Instead of simply concentrating on a limited number of extensive and pedantic coverages, scholarly diagrams are also included. - Provides a three-pronged approach to precision medicine that is focused on investigators, practitioners and healthcare providers - Covers disease groups and ancillary information about techniques, resources and consequences - Follows a structured blueprint, ensuring essential chapters items are not overlooked
Genome Plasticity in Health and Disease provides a fully up-to-date overview on genome plasticity and its role in human physiology and disease. Following an introduction to the field, a diverse range of chapters cover genomic and epigenomic analysis and the use of model organisms and genomic databases in studies. Specific molecular and biochemical mechanisms of genome plasticity are examined, including somatic variants, De Novo variants, founder variations, isolated populations dynamics, copy-number variations, mobile elements, DNA methylation, histone modifications, transcription factors, non-coding RNAs, telomere dynamics and RNA editing. Later chapters explore disease relevance for cancer, as well as cardiovascular, neuropsychiatric, inflammatory, and endocrine disease, and associated pathways for drug discovery. - Examines the role of genome plasticity across a range of disease types, from cardiovascular disease, to cancer and neuropsychiatric disorders - Adopts an interdisciplinary approach, with expert contributions across the spectrum of basic science and disease relevance to drug discovery
There is increasing regulatory interdependence amongst Central, East and South East Asia, European and North American financial markets, and these markets account for over one-third of the world’s population and global financial markets. As these Asian markets become more integral to global financial economy, more cohesive, compatible and integrated insolvency and restructuring laws are essential. This two-volume work reviews why we should internationalise current cross-border insolvency and how we could restructure laws to address inadequacies. The two-volume work evaluates international regulatory reforms directed at detecting and managing cross-border insolvency and restructuring crises...
Consider the complexity of a living cell after 3.8 billion years of evolution. Is it more awesome to suppose that a transcendent God fashioned the cell at a stroke, or to realize that it evolved with no Almighty Hand, but arose on its own in the c...
Precision Medicine in Neurodegenerative Disorders, Part One, Volume 192 in the Handbook of Clinical Neurology deals with the "Why" in the approach to slow the progression of accelerated brain aging. This volume is intended to provide a scholarly background on the framework, basic science and conceptual pitfalls related to disease-modifying efforts in Parkinson's, Alzheimer's and other neurodegenerative disorders. Among topics covered are different models of precision medicine, the lumping-versus-splitting tension in biomarker development and therapeutics, and the rationale for replacing the convergence of the prevailing autopsy-based nosology of neurodegenerative diseases with the divergence...
This groundbreaking work offers a comprehensive account of brain-based research on translation and interpreting. First, the volume introduces the methodological and conceptual pillars of psychobiological approaches vis-à-vis those of other cognitive frameworks. Next, it systematizes neuropsychological, neuroscientific, and behavioral evidence on key topics, including the lateralization of networks subserving cross-linguistic processes; their relation with other linguistic mechanisms; the functional organization and temporal dynamics of the circuits engaged by different translation directions, processing levels, and source-language units; the system’s susceptibility to training-induced pla...
Hyperhidrosis is a medical condition in which a person sweats excessively and unpredictably. People with hyperhidrosis may sweat even when the temperature is cool or when they are at rest. Despite prevalence of at least 1% of the global population, Hyperhidrosis is still an unknown entity, for the most part -- an undertreated and even neglected medical condition. Moreover, there are few sources summarizing the knowledge on hyperhidrosis to a wider audience. The purpose of this book is to provide information regarding hyperhidrosis, ranging from basic information on pathophysiology to the most advanced therapeutic alternatives. From a therapeutic perspective, hyperhidrosis requires clinical t...
The future policing ought to cover identification of new assaults, disclosure of new ill-disposed patterns, and forecast of any future vindictive patterns from accessible authentic information. Such keen information will bring about building clever advanced proof handling frameworks that will help cops investigate violations. Artificial Intelligence for Cyber Defense and Smart Policing will describe the best way of practicing artificial intelligence for cyber defense and smart policing. Salient Features: • Combines AI for both cyber defense and smart policing in one place. • Covers novel strategies in future to help cybercrime examinations and police. • Discusses different AI models to fabricate more exact techniques. • Elaborates on problematization and international issues. • Includes case studies and real-life examples. This book is primarily aimed at graduates, researchers, and IT professionals. Business executives will also find this book helpful.