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"...how a man rallies to life's challenges and weathers its storms tells everything of who he is and all that he is likely to become." —St. Augustine It has long been understood that how a person adjusts to life stresses is a major component of his or her ability to lead a fulfilling life. Yet it wasn't until the 1960s that coping became a discrete topic of psychological inquiry. Since then, coping has risen to a position of prominence in the modern psychological discourse—especially within the personality, cognitive, and behavioral spheres—and, within the past decade alone, many important discoveries have been made about its mechanisms and functioning, and its role in ongoing psycholo...
Cancer is clearly an age-related disease. Recent research in both aging and cancer has demonstrated the complex interaction between the two phenomena. This affects a wide spectrum of research and practice, anywhere from basic research to health care organization. Core examples of these close associations are addressed in this book. Starting with basic research, the first chapters cover cancer development, mTOR inhibition, senescent cells altering the tumor microenvironment, and immune senescence affecting cancer vaccine response. Taking into account the multidisciplinarity of geriatric oncology, several chapters focus on geriatric and oncologic aspects in patient assessment, treatment option...
Despite recent advances in adjuvant therapies of cancer, the regi mens of postoperative adjuvant chemotherapy treatment which are presently available fail to cure the majority of cancer patients. Pre operative (neoadjuvant) chemotherapy represents a new approach in drug scheduling, based on sound theoretical, pharmacokinetic, and experimental principles. The preoperative timing of chemotherapy before definitive sur gery is not a minor change in the therapy of cancer. To be successful, large numbers of practitioners and their patients must participate. Substantial alterations of many aspects of the present management of cancer will have to follow. Therefore, before such therapy can be fully a...
Psychosocial Resource Variables in Cancer Studies reviews the literature on selected psychosocial resource variables in cancer in order to raise and examine conceptual and methodological issues and to offer suggestions for future directions in the field. It provides investigators and clinicians with a systematic treatment of the state of the art in research on specific resource factors and provides a careful consideration of more generic methodological and statistical issues in this research context. Editors Curbow and Somerfield define resources as aspects of a person or environment that are brought to bear on the maintenance or restoration of adaptation under taxing conditions. They hope P...
Coping with Aging is the final project of the late Richard S. Lazarus, the man whose landmark book Emotion and Adaptation put the study of emotion in play in the field of psychology. In this volume, Lazarus examines the experience of aging from the standpoint of the individual, rather than as merely a collection of statistics and charts. This technique is in line with his long-standing belief that experiences should be looked at in their specific contexts, rather than squeezed into an overly general statistical viewpoint that loses the subjects' motivations. Drawing on his five decades of pioneering research, Lazarus looks at aging, emotion, and coping, and stability and change in both environment and personality. Because Lazarus mixes academic rigor with everyday examples, this volume will be both useful to scholars and accessible to the lay audience that has so much gain from a systematic understanding of aging and emotion.
A provocative and surprising investigation into the ways that profit, personalities, and politics obstruct real progress in the war on cancer—and one doctor's passionate call to action for change This year, nearly 1.6 million new cases of cancer will be diagnosed and more than 1,500 people will die per day. We've been asked to accept the disappointing strategy to "manage cancer as a chronic disease." We've allowed pharmaceutical companies to position cancer drugs that extend life by just weeks and may cost $100,000 for a single course of treatment as breakthroughs. Why have we been able to cure and prevent other killer diseases but not most cancers? Where is the bold government leadership ...
Teach effective problem-solving programs for nonprofessional cancer patient caregivers who have a limited knowledge of the disease! Family caregivers are often uninformed about what they should do with family members with cancer; they are unskilled in carrying out caregiver duties and are emotionally involved as well. The Application to Problem-Solving Therapy to Psychosocial Oncology Care will help novices and expert professionals in the areas of nursing, social work, psychology, ministry, and cancer support programs learn how to introduce problem-solving concepts that can benefit cancer patients and families in counseling sessions, formal education programs, or in everyday clinical practic...
Expert laboratory and clinical researchers from around the world review how to design and evaluate studies of tumor markers and examine their use in breast cancer patients. The authors cover both the major advances in sophisticated molecular methods and the state-of-the-art in conventional prognostic and predictive indicators. Among the topics discussed are the relevance of rigorous study design and guidelines for the validation studies of new biomarkers, gene expression profiling by tissue microarrays, adjuvant systemic therapy, and the use of estrogen, progesterone, and epidermal growth factor receptors as both prognostic and predictive indicators. Highlights include the evaluation of HER2 and EGFR family members, of p53, and of UPA/PAI-1; the detection of rare cells in blood and marrow; and the detection and analysis of soluble, circulating markers.
Developed by the American Cancer Society this new textbook designed for a wide range of learners and practitioners is a comprehensive reference covering the diagnosis of cancer, and a range of related issues that are key to a multidisciplinary approach to cancer and critical to cancer control and may be used in conjunction with the book, The American Cancer Society's Oncology in Practice: Clinical Management. Edited by leading clinicians in the field and a stellar contributor list from the US and Europe, this book is written in an easy to understand style by multidisciplinary teams of medical oncologists, radiation oncologists and other specialists, reflecting day-to-day decision-making and clinical practice. Input from pathologists, surgeons, radiologists, and other specialists is included wherever relevant and comprehensive treatment guidelines are provided by expert contributors where there is no standard recognized treatment. This book is an ideal resource for anyone seeking a deeper understanding of cancer prevention, screening, and follow-up, which are central to the ACS's worldwide mission on cancer control.