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Accompanying DVD-ROM contains ... "over 170 video clips of hjman movement disorders and the corresponding animal models."--Page 4 of cover.
The use of animal models is a key aspect of scientific research in numerous fields of medicine. This book vigorously examines the important contributions and application of animal models to the understanding of human movement disorders and will serve as an essential resource for basic neuroscientists engaged in movement disorders research. Academic clinicians, translational researchers and basic scientists are brought together to connect experimental findings made in different animal models to the clinical features, pathophysiology and treatment of human movement disorders. A vital feature of this book is an accompanying DVD with video clips of human movement disorders and their correspondin...
Clinical case studies have long been recognized as a useful adjunct to problem-based learning and continuing professional development. This book collects over 90 of the most memorable and challenging movement disorder cases from the world's leading authorities in this specialty. Compelling vignettes covering the entire phenomenology of movement disorders are presented succinctly but descriptively to walk the reader through the diagnostic process-much like being in the examining room with a master clinician. Each case follows a set format consisting of four sections: The Case; The Approach; The Lesson; Reference and Suggested Readings. Imaging findings and other illustrations amplify the discussion where pertinent.
Parkinson’s Disease and Nonmotor Dysfunction fills a major gap in the current rapidly growing body of knowledge concerning Parkinson’s disease. Drs. Pfeiffer and Bodis-Wollner have correctly perceived that many nonmotor features of Parkinson’s disease are given insufficient attention in the medical literature. Unfortunately, they are often also given insufficient attention by the practicing neurologists who see these patients. As recently pointed out, there is clearly much more to Parkinson’s disease than depletion of the nigrostriatal dopamine system (1). Parkinson’s disease (not just m- tiple system atrophy) is a multisystem disorder, both pathologically and in its clinical manif...
The field of genetics is rapidly evolving and new medical breakthroughs are occuring as a result of advances in knowledge of genetics. This series continually publishes imporatnt reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines. - Includes methods for testing with ethical, legal, and social implications
In recent years, considerable advances have been made in our knowledge and understanding of Parkinson's disease (PD). In particular, there has been an explosion of information regarding genetic contributions to the etiology of PD and an increased awareness of the importance of the non-motor features of the disease. Theories regarding the pathogenesis and pathophysiology of PD have also been refined, and new treatment modalities and advances implemented. Reflecting these changes, this second edition features new chapters devoted to genetic aspects of PD, non-motor features of the disease, and aspects of the pathophysiology, pathogenesis, and treatment of PD.
Time Distortions in Mind brings together current research on aspects of temporal processing in clinical populations, in the ultimate hope of elucidating the interdependence between perturbations in timing and disturbances in the mind and brain. Such research may inform not only typical psychological functioning, but may also elucidate the psychological consequences of any pathophysiological differences in temporal processing. This collection of current knowledge on temporal processing in clinical populations is an excellent reference for the student and scientist interested in the topic, but it also serves as the stepping-stone to share ideas and push forward the advancement in understanding...
Recent research is leading to an ever-increasing range of investigative approaches whose aim is to achieve effective neuroprotective or neurorestorative treatment for individuals affected by Parkinson‘s disease. New directions under investigation reach beyond traditional pharmacological approaches to venture into innovative surgical methods, gene t