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Mark Wigglesworth
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The Silent Musician
The conductor—tuxedoed, imposingly poised above an orchestra, baton waving dramatically—is a familiar figure even for those who never set foot in an orchestral hall. As a veritable icon for classical music, the conductor has also been subjected to some ungenerous caricatures, presented variously as unhinged gesticulator, indulged megalomaniac, or even outright impostor. Consider, for example: Bugs Bunny as Leopold Stokowski, dramatically smashing his baton and then breaking into erratic poses with a forbidding intensity in his eyes, or Mickey Mouse in Fantasia, unwittingly conjuring dangerous magic with carefree gestures he doesn’t understand. As these clichés betray, there is an aura...
High Throughput Screening
"High Throughput Screening (HTS) is one of several hit identification approaches that are part of a developing and evolving toolbox for the discovery of pharmaceutical start points. HTS remains one of the most successful approaches, and therefore an important foundation of drug discovery. In High Throughput Screening: Methods, Techniques and Applications, leading industrial and academic experts in screening and drug discovery explain key technologies and methods while demonstrating how they can be applied to successful hit identification. Describing both traditional and emerging methods in detail, this book provides an overview of these methods to the reader that will serve both those new to...
Management of Chemical and Biological Samples for Screening Applications
Filling an obvious gap in the scientific literature, this practice-oriented reference is the first to tie together the working knowledge of large screening centers in the pharmaceutical and biotechnological field. It spans the entire fi eld of this emerging discipline, from compound acquisition to collection optimization for specific purposes, to technology and quality control. In so doing, it applies two decades of expertise gathered by several large pharmaceutical companies to current and future challenges in high-throughput screening. With its treatment of libraries of small molecules as well as biobanks containing biomolecules, microorganisms and tissue samples, this reference is universally applicable for any molecular scientist involved in a large screening program.
Critical Architecture
Critical Architecture examines the relationship between critical practice in architecture and architectural criticism. Placing architecture in an interdisciplinary context, the book explores architectural criticism with reference to modes of criticism in other disciplines - specifically art criticism - and considers how critical practice in architecture operates through a number of different modes: buildings, drawings and texts. With forty essays by an international cast of leading architectural academics, this accessible single source text on the topical subject of architectural criticism is ideal for undergraduate as well as post graduate study.
Perspectives on Conducting
Rooted in research and practice, Perspectives on Conducting presents a multi-faceted exploration of the role of the modern-day conductor. Seeking to bring a more inclusive approach to understanding conducting as a career, this book expands beyond elite pathways to highlight the contributions made by conductors across different areas of musical engagement, including youth projects, community groups, and professional ensembles. Chapters by an international roster of authors address the challenges conductors face in working with a wide range of ensembles, including orchestras and choirs made up of young people, university and conservatory students, adult volunteers, and professional musicians. ...
The Mahler Companion
'the one-stop guide to Mahler -- a volume of essays covering the widest range of Mahlerian topics, designed both for the academic and serious amateur music-lover... The core of the compendium is its coverage of all the main works, carrying recent research, with plentiful musical examples and other illustrations.' -Andrew Green, Classical Music 08/11/1999'beautifully produced volume... a tribute that surveys the familiar with affectionate new insights... all the articles on Mahler's reception outside Austria, both during his life and after, make for fascinating reading.' -David Nice, BBC Music Magazine October 1999'The Mahler Companion constitutes a distinguished and fitting monument to Mitch...
High Throughput Screening
In High Throughput Screening, leading scientists and researchers expert in molecular discovery explain the diverse technologies and key techniques used in HTS and demonstrate how they can be applied generically. Writing to create precisely the introductory guidebook they wish had been available when they started in HTS, these expert seasoned authors illuminate the HTS process with richly detailed tutorials on the biological techniques involved, the management of compound libraries, and the automation and engineering approaches needed. Extensive discussions provide readers with all those key elements of pharmacology, molecular biology, enzymology, and biochemistry that will ensure the identification of suitable targets and screens, and detail the technology necessary to mine millions of data points for meaningful knowledge.
Ever Increasing Faith
Smith Wigglesworth was born to a very poor family. At the age of six he had to go to work. As a consequence, he never learned to read well until he was an adult. He became a plumber by trade. As a minister, Wigglesworth was hardly known outside of his hometown until 1907. In 1907, he received the baptism in the Holy Ghost, which changed his life forever. It was then, at the age of 48, that God moved Wigglesworth from a small relatively unknown ministry to conducting powerful meetings throughout the world, stirring the faith of thousands to receive healing and salvation. Wigglesworth would usually conclude a sermon by praying for the sick; regardless of what text he had ministered. Smith Wigglesworth's ministry centred on salvation for the unconverted, healing for the sick, and a call to believers to be baptized in the Holy Ghost. He was filled with God...with love, compassion, and faith. On March 12, 1947, Smith Wigglesworth, in perfect health, closed his eyes and slipped into eternity, at the age of 87.
