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Microextraction Techniques in Analytical Toxicology
Microextraction Techniques in Analytical Toxicology provides the information readers need to include about cutting-edge sample preparation techniques into their everyday analytical practice, including comprehensive information about principles and state-of-the-art microextraction sample preparation techniques for the analysis of drugs and poisons in biological specimens, especially in forensic and clinical settings. This book also focuses on theoretical discussions of solid-based and liquid-based microextraction techniques, their method development, validation, and applications. A detailed compilation of analytical protocols based on published microextraction procedures to aid in method deve...
Cannabis and Khat in Drug Discovery
Cannabis and Khat in Drug Discovery: The Discovery Pipeline and the Endocannabinoid System provides comprehensive coverage of two important psychoactive plants: Khat and Cannabis. Initial research has found that compounds and derivatives from Cannabis and Khat are found to have promising properties that can be used for the discovery, design and development of potential drug leads against various diseases. This book extensively discusses the drug discovery and allied sciences of these compounds in the drug discovery pipeline, including basic research and computer aided modeling in ligand-drug interactions and their interactions with the endocannabinoid system. Categorized into sections includ...
Quantitative and Qualitative Determination Technologies of Counterfeit Drugs
Drugs are often counterfeited to reduce manufacture costs, while still marketing it at as an authentic product. Increased incidence of drug counterfeiting is most noticeable in developing countries, which may not have the resources to supply counterfeit detection devices on a large scale. It is important to consider the problems caused and to propose options for controlling and reducing the prevalence of counterfeit medications. Various technologies are needed to identify the chemical properties of a questioned medicinal product, which can then be used to determine its authenticity. This volume focuses on current technological approaches that are able to detect counterfeited pharmaceuticals....
Wastewater-Based Epidemiology
Evaluating wastewater contaminants can enable a community to understand drug consumption, from antibiotics to illegal substances and even diet. Wastewater-based epidemiology has emerged as a cost- and time-effective monitoring tool. The contributed chapters cover the methodological challenges and applications of wastewater-based epidemiology. In addition to public health professionals, wastewater and chemical engineers, students, educators, and administrators will find these topics useful.
Drug-Facilitated Sexual Assault
Drug-Facilitated Sexual Assault educates readers on the ways in which drugs are used as weapons in committing sexual assaults and how to successfully investigate these crimes. It looks at the history of these crimes over the years, and includes an in-depth discussion of the drugs and drug classes in use today. It describes the effects of these drugs on the victims, the process for reporting these crimes, details on the type of person who uses drugs to sexually assault an individual, and obstacles to investigating the suspect. The authors show the proper techniques in collecting and analyzing evidence; ways to overcome some of the unique difficulties encountered in these types of investigatio...
The Challenge Posed by New Synthetic Opioids: Pharmacology and Toxicology
New Synthetic Opioids (NSOs), most of which are illegally produced and sold for recreational use, are posing a serious threat to the health of consumers. Due to the low cost of materials and equipment required for clandestine laboratories production with respect to the production cost of heroin, NSOs are climbing the illegal street and web drug market. Several of these drugs have been involved in a recent rise in acute intoxications and overdose deaths. Since NSOs offer enormous profit potential, and there is strong demand for their use, these drugs are being trafficked by organized crime and present major challenges for medical professionals facing intoxications and fatalities, law enforcement agencies fighting against their diffusion and policymakers trying to restrain the use and abuse of NSOs. This Research Topic aimed to fill the gap on current knowledge on pharmacology and toxicology, health risks for adult and newborns of NSOs covering both basic scientific as well as epidemiological and clinical aspects. 3 reviews, 3 mini-reviews, 1 original article, 2 case reports and 1 opinion are here presented.
The Analysis of Drugs of Abuse
The Analysis of Drugs of Abuse Edited by Terry A. Gough, The Laboratory of the Government Chemist, Teddington, UK Analytical techniques based on separation processes, such as chromatography and electrophoresis, are finding a growing range of applications in chemical, biochemical and clinical laboratories: The aim of this series is to provide the analyst in these laboratories with well-focused books covering individual techniques and methods. This volume, devoted to the analysis of drugs which are commonly misused, provides a comprehensive source of up-to-date information. Detailed individual chapters are written by experts in the field describing various analytical techniques and applications. A special feature of the book is its emphasis on the complementary roles of chemist, law enforcer and the law maker in combatting drugs smuggling and the need for collaboration. This book will be a valuable reference for chemists, toxicologists and forensic scientists working in the field.
Liquid Chromatography/Mass Spectrometry, MS/MS and Time of Flight MS
This volume explores state-of-the-art mass spectrometric techniques. It focuses on liquid chromatography/mass spectrometry/mass spectrometry and time-of-flight/mass spectrometry to determine emerging contaminants, such as pharmaceuticals, hormones, pesticides, surfactants and unknown natural products.
