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Telomeres, Diet and Human Disease
The maintenance of telomeres—repetitive sequences at the end of chromosome—is essential to health. Dysfunction in telomere maintenance pathways plays a role in aging, cancer, atherosclerosis and other diseases. This has led to telomere maintenance as a prime target for patient therapies. This book describes the advances in telomere research as it applies to human health and especially how lifestyle and dietary factors could modify the telomerase maintenance process. The book examines the mechanisms involved, the primary of which are oxidative stress and the role of sirtuins, and how they can be modified by dietary patterns such as Mediterranean diet.
The View from Castle Rock
WINNER OF THE NOBEL PRIZE IN LITERATURE The world's finest living short story writer turns to her family for inspiration; and what follows is a fictionalised, brilliantly imagined version of the past. From her ancestors' view from Edinburgh's Castle Rock in the eighteenth century to her parents' thwarted ambitions in Ontario, and her own awakening in 1950s Canada, Munro effortlessly weaves fact and myth to create an epic story of past and present, proving that fiction has much to tell us about life.
Pyramids at the Louvre
Throughout, collage asserts its power to enlighten through juxtaposition, resist resolution, sponsor pluralism, and promote understanding of an order that eludes all edicts.
The Fever
THE STORY: The nameless narrator of this blistering monologue lies ill and alone in a dreary hotel room in a poverty-stricken country. A political execution is about to take place beneath his window. Far from the glib comforts of his own life, he s
1937
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The Gesualdo Hex: Music, Myth, and Memory
A riveting investigation of one of the most provocative musicians of the Renaissance, who continues to captivate composers, artists, and audiences today. In this vivid tale of adultery and intrigue, witchcraft and murder, Glenn Watkins explores the fascinating life of the Renaissance composer Carlo Gesualdo—a life suffused with scandal and bordering on the fantastical. An isolated prince, Gesualdo had a personal life that was no less eccentric and bewildering than the music he composed; his biography has often clouded our perception of his oeuvre, which music scholars have periodically dismissed as a late Renaissance deformation of little consequence. Today, however, Gesualdo’s music, on...
